Protein Alignment HSPG2 and Hspg2

DIOPT Version :9

• Sequence 1: XP_011539620.1
• Gene: HSPG2 / 3339
• HGNCID: 5273
• Length: 4574
• Species: Homo sapiens
• Sequence 2: XP_038967228.1
• Gene: Hspg2 / 313641
• RGDID: 621770
• Length: 4551
• Species: Rattus norvegicus
• Alignment Length: 4585
• Identity: 3918/4585 - (85%)
• Similarity: 4164/4585 - (90%)
• Gaps: 45/4585 - (0%)

Human     1 MGWRAAGALLLALLLHGRLLAVTHGLRAYDGLSLPEDIETVTASQMRWTHSYLSDDEDMLADSIS 65
            ||.||.|:|||.||||.||||||.|||||||||||||.||||||:..||:||||||||:|||..|
  Rat     1 MGQRAVGSLLLGLLLHARLLAVTQGLRAYDGLSLPEDTETVTASRYGWTYSYLSDDEDLLADDAS 65

Human    66 GDDLGSGDLGSGDFQMVYFRALVNFTRSIEYSPQLEDAGSREFREVSEAVVDTLESEYLKIPGDQ 130
            ||.|||||||||||||||||||||||||||||||||||.::||||||||||:.||:||:||||||
  Rat    66 GDGLGSGDLGSGDFQMVYFRALVNFTRSIEYSPQLEDANAKEFREVSEAVVEKLETEYVKIPGDQ 130

Human   131 VVSVVFIKELDGWVFVELDVGSEGNADGAQIQEMLLRVISSGSVASYVTSPQGFQFRRLGTAQTP 195
            :|||||||||||||||||||||||||||:||||:|..|:||||:..|||||.||:||||||||||
  Rat   131 IVSVVFIKELDGWVFVELDVGSEGNADGSQIQEVLHTVVSSGSIGPYVTSPWGFKFRRLGTAQTP 195

Human   196 PPPPAAVAVAVTPVPQFPRACTEAEFACHSYNECVALEYRCDRRPDCRDMSDELNCEEPVLGISP 260
            |||||||.|||||||||||.|||.||||||||||||||||||||||||||||||||||.|..||.
  Rat   196 PPPPAAVGVAVTPVPQFPRVCTETEFACHSYNECVALEYRCDRRPDCRDMSDELNCEEAVSEISS 260

Human   261 TFSLLVETTSLPPRPETTIMRQPPVTHAPQPLLPGSVRPLPCGPQEAACRNGHCIPRDYLCDGQE 325
            ..|.:|:.:.||..||...: .|||.|.||.|||....|..||||||:|.:||||||||||||||
  Rat   261 LPSAVVKVSPLPLWPEAATL-PPPVMHGPQFLLPNVPGPTACGPQEASCHSGHCIPRDYLCDGQE 324

Human   326 DCEDGSDELDCGPPPPCEPNEFPCGNGHCALKLWRCDGDFDCEDRTDEANCPTKRPEEVCGPTQF 390
            ||.||||||.||||||||||||.|.|||||||||||||||||||.|||||||.|.|.||||||||
  Rat   325 DCRDGSDELGCGPPPPCEPNEFSCENGHCALKLWRCDGDFDCEDHTDEANCPVKHPGEVCGPTQF 389

Human   391 RCVSTNMCIPASFHCDEESDCPDRSDEFGCMPPQVVTPPRESIQASRGQTVTFTCVAIGVPTPII 455
            :|||||.|||||||||||:||||||||||||||||||||::||||||||||||||||.|||||||
  Rat   390 QCVSTNRCIPASFHCDEETDCPDRSDEFGCMPPQVVTPPQQSIQASRGQTVTFTCVATGVPTPII 454

Human   456 NWRLNWGHIPSHPRVTVTSEGGRGTLIIRDVKESDQGAYTCEAMNARGMVFGIPDGVLELVPQRA 520
            ||||||||||.:||||:||||||||||||||||:|||||||||||:||||||||||||||||||
  Rat   455 NWRLNWGHIPVNPRVTMTSEGGRGTLIIRDVKEADQGAYTCEAMNSRGMVFGIPDGVLELVPQR- 518

Human   521 GPCPDGHFYLEHSAACLPCFCFGITSVCQSTRRFRDQIRLRFDQPDDFKGVNVTMPAQPGTPPLS 585
            |||||||||||.||:||||||||:|::|||:|||||||||.||||.||||||||||:|||.||||
  Rat   519 GPCPDGHFYLEDSASCLPCFCFGVTNLCQSSRRFRDQIRLNFDQPSDFKGVNVTMPSQPGVPPLS 583

Human   586 STQLQIDPSLHEFQLVDLSRRFLVHDSFWALPEQFLGNKVDSYGGSLRYNVRYELARGMLEPVQR 650
            ||||||||:|.|||||||||||||||:|||||:||||||||||||.|||.||||||||||||||:
  Rat   584 STQLQIDPTLQEFQLVDLSRRFLVHDAFWALPKQFLGNKVDSYGGFLRYKVRYELARGMLEPVQK 648

Human   651 PDVVLMGAGYRLLSRGHTPTQPGALNQRQVQFSEEHWVHESGRPVQRAELLQVLQSLEAVLIQTV 715
            |||:|:||||||.|||||||.||||||||||.|||||||||||||||||:||.|.||||||:|||
  Rat   649 PDVILVGAGYRLHSRGHTPTHPGALNQRQVQLSEEHWVHESGRPVQRAEMLQALASLEAVLLQTV 713

Human   716 YNTKMASVGLSDIAMDTTVTHATSHGRAHSVEECRCPIGYSGLSCESCDAHFTRVPGGPYLGTCS 780
            |||||.|||||||.||||||:.|.|||||||||||||||||||||||||||||||||||||||||
  Rat   714 YNTKMTSVGLSDIVMDTTVTYTTIHGRAHSVEECRCPIGYSGLSCESCDAHFTRVPGGPYLGTCS 778

Human   781 GCNCNGHASSCDPVYGHCLNCQHNTEGPQCNKCKAGFFGDAMKATATSCRPCPCPYIDASRRFSD 845
            ||||||||||||||||||||||||||||||:|||.||||||.|||||:||||||||||||:||||
  Rat   779 GCNCNGHASSCDPVYGHCLNCQHNTEGPQCDKCKPGFFGDATKATATACRPCPCPYIDASQRFSD 843

Human   846 TCFLDTDGQATCDACAPGYTGRRCESCAPGYEGNPIQPGGKCRPVNQEIVRCDERGSMGTSGEAC 910
            ||||||||||||||||||||||||||||||||||||||||||||.|||:||||||||:..:||||
  Rat   844 TCFLDTDGQATCDACAPGYTGRRCESCAPGYEGNPIQPGGKCRPSNQELVRCDERGSLSATGEAC 908

Human   911 RCKNNVVGRLCNECADGSFHLSTRNPDGCLKCFCMGVSRHCTSSSWSRAQLHGASEEPGHFSLTN 975
            |||||||||.||||::||||||.:|||||||||||||||.|:||||||||:.|||.:|..|:|||
  Rat   909 RCKNNVVGRSCNECSEGSFHLSKQNPDGCLKCFCMGVSRQCSSSSWSRAQVLGASVQPSQFTLTN 973

Human   976 AASTHTTNEGIFSPTPGELGFSSFHRLLSGPYFWSLPSRFLGDKVTSYGGELRFTVTQRSQPGST 1040
            ||.||||:||:.||.||||.|||||.|||.|||||||:.|.||||||||||||||||||.:|||.
  Rat   974 AAGTHTTSEGVSSPAPGELLFSSFHNLLSEPYFWSLPASFRGDKVTSYGGELRFTVTQRPRPGSA 1038

Human  1041 PLHGQPLVVLQGNNIILEHHVAQEPSPGQPSTFIVPFREQAWQRPDGQPATREHLLMALAGIDTL 1105
            |||.|||||||||||:||||.::||||||||.|||||:||.||||||||||||||||||||||.|
  Rat  1039 PLHRQPLVVLQGNNIVLEHHASREPSPGQPSNFIVPFQEQVWQRPDGQPATREHLLMALAGIDAL 1103

Human  1106 LIRASYAQQPAESRVSGISMDVAVPEETGQDPALEVEQCSCPPGYRGPSCQDCDTGYTRTPSGLY 1170
            ||:||:.|||||||:|||||||||||.||||||.|||.|:|||||||||||||||||||..||||
  Rat  1104 LIQASHTQQPAESRLSGISMDVAVPENTGQDPAREVEHCTCPPGYRGPSCQDCDTGYTRVASGLY 1168

Human  1171 LGTCERCSCHGHSEACEPETGACQGCQHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAA 1235
            |||||||:||||||.|||||||||.|||||||..|||||||||||.|||||||||.|||||.|||
  Rat  1169 LGTCERCNCHGHSETCEPETGACQSCQHHTEGASCEQCQPGYYGDPQRGTPQDCQPCPCYGTPAA 1233

Human  1236 GQAAHTCFLDTDGHPTCDACSPGHSGRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGS 1300
            |||:||||||||||||||:|||||||||||||||||:|||||||||.||.|||...||:|||.||
  Rat  1234 GQASHTCFLDTDGHPTCDSCSPGHSGRHCERCAPGYHGNPSQGQPCHRDGQVPEVPGCDCDPHGS 1298

Human  1301 VSSQCDAAGQCQCKAQVEGLTCSHCRPHHFHLSASNPDGCLPCFCMGITQQCASSAYTRHLISTH 1365
            :||||||.|||||||||||.|||||||||||||||||:|||||||||:||||.||:|:|.|||||
  Rat  1299 ISSQCDATGQCQCKAQVEGRTCSHCRPHHFHLSASNPEGCLPCFCMGVTQQCTSSSYSRQLISTH 1363

Human  1366 FAPGDFQGFALVNPQRNSRLTGEFTVEPVPEGAQLSFGNFAQLGHESFYWQLPETYQGDKGEAYF 1430
            ||||||||||||||||||:|||.|||||||:||:|||.|||.||.|||||||||||||||.||:|
  Rat  1364 FAPGDFQGFALVNPQRNSQLTGGFTVEPVPDGARLSFSNFAHLGQESFYWQLPETYQGDKREAHF 1428

Human  1431 ARMRRAHQRTLPMALAPGLWEVLARLLPPFHQNRTSLSEEQLRAAVTAGRIPEPPEGRDWAQRAS 1495
            ||:|||                        ||||||||||:.||||.:|||....|||..|||||
  Rat  1429 ARLRRA------------------------HQNRTSLSEEEWRAAVASGRILGDTEGRGRAQRAS 1469

Human  1496 QVDEAQRRMDAEIWQLLSSFAAQPQPPPQGLSPHPQPAAALRAAPPPSSSSSSSSSSA--SLSFS 1558
            ||||||||:||||||||:.|||.|.|||:||.|:||.|.||||.||.||||||.|||:  ||...
  Rat  1470 QVDEAQRRVDAEIWQLLAGFAAHPHPPPRGLRPNPQLATALRAGPPSSSSSSSPSSSSFTSLPSP 1534

Human  1559 PGSQFSLSYEGFSLLPGSLYYWQLPRAFLGDKVAAYGGKLRYTLSYTAGPQGSPLSDPDVQITGN 1623
            .|||||||||||||||||||||||||||||:||||||||||||||||:|||||||||||:|||||
  Rat  1535 AGSQFSLSYEGFSLLPGSLYYWQLPRAFLGNKVAAYGGKLRYTLSYTSGPQGSPLSDPDIQITGN 1599

Human  1624 NIMLVASQPALQGPERRSYEIMFREEFWRRPDGQPATREHLLMALADLDELLIRATFSSVPLAAS 1688
            |||||||||||||||||||||:||||||||||||||||||||||||||||||:||||||||.|||
  Rat  1600 NIMLVASQPALQGPERRSYEIIFREEFWRRPDGQPATREHLLMALADLDELLVRATFSSVPRAAS 1664

Human  1689 ISAVSLEVAQPGPSNRPRALEVEECRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECNGHSD 1753
            ||||||||||||||..|:|||||||||||||:|||||||||||||||||||||.||||||||||:
  Rat  1665 ISAVSLEVAQPGPSGGPQALEVEECRCPPGYVGLSCQDCAPGYTRTGSGLYLGQCELCECNGHSE 1729

Human  1754 LCHPETGACSQCQHNAAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGG 1818
            :||||||||:.||||..|||||.||.|||||||||||||||||||||||||||||||||||||||
  Rat  1730 VCHPETGACTGCQHNTVGEFCETCATGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGG 1794

Human  1819 YRCTACEPGYTGQYCEQCGPGYVGNPSVQGGQCLPETNQAPLVVEVHPARSIVPQGGSHSLRCQV 1883
            ||||||||||||||||||.|||.|||:||||:|.|.|.:: |.|::||:||:|||||.|||||||
  Rat  1795 YRCTACEPGYTGQYCEQCAPGYEGNPNVQGGRCQPLTKES-LEVQIHPSRSVVPQGGPHSLRCQV 1858

Human  1884 SGSPPHYFYWSREDGRPVPSGTQQRHQGSELHFPSVQPSDAGVYICTCRNLHQSNTSRAELLVTE 1948
            :||||||||||||||||:|||.|||||||||||||||||||||||||||||..::.|||||||.|
  Rat  1859 NGSPPHYFYWSREDGRPLPSGAQQRHQGSELHFPSVQPSDAGVYICTCRNLIHTSNSRAELLVAE 1923

Human  1949 APSKPITVTVEEQRSQSVRPGADVTFICTAKSKSPAYTLVWTRLHNGKLPTRAMDFNGILTIRNV 2013
            ||||||||||||||||||||||||||||||||||||||||||||||||||:||||||||||||||
  Rat  1924 APSKPITVTVEEQRSQSVRPGADVTFICTAKSKSPAYTLVWTRLHNGKLPSRAMDFNGILTIRNV 1988

Human  2014 QLSDAGTYVCTGSNMFAMDQGTATLHVQASGTLSAPVVSIHPPQLTVQPGQLAEFRCSATGSPTP 2078
            |.||||||||||||||||||||||||||.|||.:|||.|||||||||||||||||||||||:|||
  Rat  1989 QPSDAGTYVCTGSNMFAMDQGTATLHVQVSGTSTAPVASIHPPQLTVQPGQLAEFRCSATGNPTP 2053

Human  2079 TLEWTGGPGGQLPAKAQIHGGILRLPAVEPTDQAQYLCRAHSSAGQQVARAVLHVHGGGGPRVQV 2143
            ||||.|||.||||.|||||.|||||||:||:||.||||||.|||||.|.||:|.||||.||||||
  Rat  2054 TLEWIGGPSGQLPTKAQIHNGILRLPAIEPSDQGQYLCRALSSAGQHVVRAMLQVHGGSGPRVQV 2118

Human  2144 SPERTQVHAGRTVRLYCRAAGVPSATITWRKEGGSLPPQARSERTDIATLLIPAITTADAGFYLC 2208
            ||||||||.||||||||||||||||:|||||||||||||||||.|||.|||||||..||:|||||
  Rat  2119 SPERTQVHEGRTVRLYCRAAGVPSASITWRKEGGSLPPQARSENTDIPTLLIPAIRVADSGFYLC 2183

Human  2209 VATSPAGTAQARIQVVVLSASDASPPPVKIESSSPSVTEGQTLDLNCVVAGSAHAQVTWYRRGGS 2273
            |||||.|||||||||||||||.||..||:||||||||||||||||||.|.|..:.|||||:||||
  Rat  2184 VATSPTGTAQARIQVVVLSASGASSVPVRIESSSPSVTEGQTLDLNCAVMGLTYTQVTWYKRGGS 2248

Human  2274 LPPHTQVHGSRLRLPQVSPADSGEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVPGSTRPIR 2338
            ||||.|||||||||||||||||||||||||:..|||||||.|||||..||||||||...||.|||
  Rat  2249 LPPHAQVHGSRLRLPQVSPADSGEYVCRVESDLGPKEASIVVSVLHSPHSGPSYTPATSSTPPIR 2313

Human  2339 IEPSSSHVAEGQTLDLNCVVPGQAHAQVTWHKRGGSLPARHQTHGSLLRLHQVTPADSGEYVCHV 2403
            ||.||||||||||||||||||||  |||||.||||||||||||||||||||||:|||||||||||
  Rat  2314 IESSSSHVAEGQTLDLNCVVPGQ--AQVTWRKRGGSLPARHQTHGSLLRLHQVSPADSGEYVCHV 2376

Human  2404 VGTSGPLEASVLVTIEASV---IPGPIPPVRIESSSSTVAEGQTLDLSCVVAGQAHAQVTWYKRG 2465
            :..|..:|.||||.||.:|   .|||:|||||||||.||||||||||:|||||||||||||||||
  Rat  2377 LLGSEHIETSVLVAIEPAVSIPAPGPVPPVRIESSSPTVAEGQTLDLNCVVAGQAHAQVTWYKRG 2441

Human  2466 GSLPARHQVRGSRLYIFQASPADAGQYVCRASNGMEASITVTVTGTQGANLAYPAGSTQPIRIEP 2530
            .||||||||||||||||||||||||:|||||.||.||:|||.|||.||||:|||.|||..||||.
  Rat  2442 SSLPARHQVRGSRLYIFQASPADAGEYVCRAGNGQEATITVKVTGNQGANIAYPPGSTPTIRIES 2506

Human  2531 SSSQVAEGQTLDLNCVVPGQSHAQVTWHKRGGSLPVRHQTHGSLLRLYQASPADSGEYVCRVLGS 2595
            |||.|||||||||||||.||:||||||||||||||.|||||||||||:|.||.|||||||||.|.
  Rat  2507 SSSHVAEGQTLDLNCVVQGQAHAQVTWHKRGGSLPARHQTHGSLLRLHQVSPVDSGEYVCRVEGG 2571

Human  2596 SVPLEASVLVTIEPAGSVPALGVTPTVRIESSSSQVAEGQTLDLNCLVAGQAHAQVTWHKRGGSL 2660
            .||||:||||.||||||||||||||.||||||||.|:|||:||||||||||.|.|::||||||||
  Rat  2572 PVPLESSVLVAIEPAGSVPALGVTPPVRIESSSSHVSEGQSLDLNCLVAGQTHPQISWHKRGGSL 2636

Human  2661 PARHQVHGSRLRLLQVTPADSGEYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSS 2725
            |||||||||||||||||||||||||||||..|||.||||||||||.||.||.|.|.:||||||||
  Rat  2637 PARHQVHGSRLRLLQVTPADSGEYVCRVVSGSGTHEASVLVTIQQHLSPSHPQSVVHPVRIESSS 2701

Human  2726 ASLANGHTLDLNCLVASQAPHTITWYKRGGSLPSRHQIVGSRLRIPQVTPADSGEYVCHVSNGAG 2790
            .||||||||||||||||..||||||||||||||||||||||||||||||||||||||||||||.|
  Rat  2702 PSLANGHTLDLNCLVASLTPHTITWYKRGGSLPSRHQIVGSRLRIPQVTPADSGEYVCHVSNGVG 2766

Human  2791 SRETSLIVTIQGSGSSHVPSVSPPIRIESSSPTVVEGQTLDLNCVVARQPQAIITWYKRGGSLPS 2855
            |:||||||||:..|.|||||||||:|||:|||||.|||||||||||..:|||.|||||||||||.
  Rat  2767 SQETSLIVTIESRGPSHVPSVSPPMRIETSSPTVTEGQTLDLNCVVVGRPQATITWYKRGGSLPF 2831

Human  2856 RHQTHGSHLRLHQMSVADSGEYVCRANNNIDALEASIVISVSPSAGSPSAPGSSMPIRIESSSSH 2920
            |||.|||.||||||||||||||||||||||||.|.||:|||||:..:|||..|.:||||||||||
  Rat  2832 RHQAHGSRLRLHQMSVADSGEYVCRANNNIDAQETSIMISVSPNTNAPSASASPVPIRIESSSSH 2896

Human  2921 VAEGETLDLNCVVPGQAHAQVTWHKRGGSLPSHHQTRGSRLRLHHVSPADSGEYVCRVMGSSGPL 2985
            ||||:||||||||||||||||||||||||||:|||..||||||:.|||||||||||||:.|||||
  Rat  2897 VAEGQTLDLNCVVPGQAHAQVTWHKRGGSLPAHHQAHGSRLRLYQVSPADSGEYVCRVLSSSGPL 2961

Human  2986 EASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDLKCVVPGQAHAQVTWHKRGGNL 3050
            ||||||:|.||.|: |||  |||.||||||.|||:|||||||||.||||||||||||||||||:|
  Rat  2962 EASVLVSITASASN-VHV--PGGVPPIRIETSSSQVAEGQTLDLTCVVPGQAHAQVTWHKRGGSL 3023

Human  3051 PARHQVHGPLLRLNQVSPADSGEYSCQVTGSSGTLEASVLVTIEPSSPGPIPAPGLAQPIYIEAS 3115
            ||.|||||.:||||:|||||||||||||||||||||||||||||.|.|.||||||||||||||:|
  Rat  3024 PAGHQVHGHILRLNRVSPADSGEYSCQVTGSSGTLEASVLVTIEASQPSPIPAPGLAQPIYIESS 3088

Human  3116 SSHVTEGQTLDLNCVVPGQAHAQVTWYKRGGSLPARHQTHGSQLRLHLVSPADSGEYVCRAASGP 3180
            |||:.||||:||||||||||||||||:|||.|||||||||||.|||:.:||||||||||:.|...
  Rat  3089 SSHLAEGQTVDLNCVVPGQAHAQVTWHKRGSSLPARHQTHGSLLRLYHISPADSGEYVCQVAGSS 3153

Human  3181 GPEQEASFTVTVPPSEGSSYRLRSPVISIDPPSSTVQQGQDASFKCLIHDGAAPISLEWKTRNQE 3245
            .||.||||.:|||.|||||||||||||||:|||||||||||||||||||:||.||||||||||||
  Rat  3154 HPEHEASFKITVPASEGSSYRLRSPVISIEPPSSTVQQGQDASFKCLIHEGATPISLEWKTRNQE 3218

Human  3246 LEDNVHISPNGSIITIVGTRPSNHGTYRCVASNAYGVAQSVVNLSVHGPPTVSVLPEGPVWVKVG 3310
            |||||||||||||:||||.||||||.|||||||.||||||||||.|||||||||||||||.||:|
  Rat  3219 LEDNVHISPNGSIMTIVGARPSNHGAYRCVASNVYGVAQSVVNLIVHGPPTVSVLPEGPVHVKMG 3283

Human  3311 KAVTLECVSAGEPRSSARWTRISSTPAKLEQRTYGLMDSHAVLQISSAKPSDAGTYVCLAQNALG 3375
            |.:||||||:||||||.||||: ..|.|||.|.:|||:|||:|:|:|.||||||||||.||||||
  Rat  3284 KDITLECVSSGEPRSSPRWTRL-GIPVKLEPRMFGLMNSHAMLKIASVKPSDAGTYVCQAQNALG 3347

Human  3376 TAQKQVEVIVDTGAMAPGAPQVQAEEAELTVEAGHTATLRCSATGSPAPTIHWSKLRSPLPWQHR 3440
            |||||||:|||||.:||||||||.||||||:||||||||.|||||:|.|||||||||:|||||||
  Rat  3348 TAQKQVELIVDTGTVAPGAPQVQVEEAELTLEAGHTATLHCSATGNPPPTIHWSKLRAPLPWQHR 3412

Human  3441 LEGDTLIIPRVAQQDSGQYICNATSPAGHAEATIILHVESPPYATTVPEHASVQAGETVQLQCLA 3505
            :||:||:|||||||||||||||||:.|||.|||::|||||.||||.:|||.|||.|:.|||||||
  Rat  3413 IEGNTLVIPRVAQQDSGQYICNATNSAGHTEATVVLHVESHPYATIIPEHTSVQPGKLVQLQCLA 3477

Human  3506 HGTPPLTFQWSRVGSSLPGRATARNELLHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPG 3570
            |||||||:||||||..||.:|.|||:||..|.|...|||||||:|:|||||||||||:||||..|
  Rat  3478 HGTPPLTYQWSRVGGILPEKAVARNQLLRLEPAGRADSGRYRCQVSNKVGSAEAFAQVLVQGSSG 3542

Human  3571 SLPATSIPAGSTPTVQVTPQLETKSIGASVEFHCAVPSDRGTQLRWFKEGGQLPPGHSVQDGVLR 3635
            .:|.||.|.|||||||||||.||||||||||||||||::.||.|||.||||||||||||||||||
  Rat  3543 DVPDTSTPVGSTPTVQVTPQQETKSIGASVEFHCAVPNEHGTHLRWLKEGGQLPPGHSVQDGVLR 3607

Human  3636 IQNLDQSCQGTYICQAHGPWGKAQASAQLVIQALPSVLINIRTSVQTVVVGHAVEFECLALGDPK 3700
            |||||||||||||||||||||:|||:|||::|||||||||:||||.:|||||:||||||||||||
  Rat  3608 IQNLDQSCQGTYICQAHGPWGQAQATAQLIVQALPSVLINVRTSVHSVVVGHSVEFECLALGDPK 3672

Human  3701 PQVTWSKVGGHLRPGIVQSGGVVRIAHVELADAGQYRCTATNAAGTTQSHVLLLVQALPQISMPQ 3765
            ||||||||||.||.||||||.|:|||||||||||||||.|||||||||||||||||||||||.|.
  Rat  3673 PQVTWSKVGGRLRSGIVQSGSVIRIAHVELADAGQYRCAATNAAGTTQSHVLLLVQALPQISTPP 3737

Human  3766 EVRVPAGSAAVFPCIASGYPTPDISWSKLDGSLPPDSRLENNMLMLPSVRPQDAGTYVCTATNRQ 3830
            ||||||||||||||:|||||||.|:|||:||.|||||||||||||||||||:|||||||||||||
  Rat  3738 EVRVPAGSAAVFPCMASGYPTPAITWSKVDGDLPPDSRLENNMLMLPSVRPEDAGTYVCTATNRQ 3802

Human  3831 GKVKAFAHLQVPERVVPYFTQTPYSFLPLPTIKDAYRKFEIKITFRPDSAD------GMLLYNGQ 3889
            |||||||:|||||||||||||||||||||||||||||||||||||||||||      ||||||||
  Rat  3803 GKVKAFAYLQVPERVVPYFTQTPYSFLPLPTIKDAYRKFEIKITFRPDSADGLLLYSGMLLYNGQ 3867

Human  3890 KRVPGSPTNLANRQPDFISFGLVGGRPEFRFDAGSGMATIRHPTPLALGHFHTVTLLRSLTQGSL 3954
            |..||||||||||||||||||||||||||||||||||||||||||||||.||||||||||||||:
  Rat  3868 KHTPGSPTNLANRQPDFISFGLVGGRPEFRFDAGSGMATIRHPTPLALGQFHTVTLLRSLTQGSM 3932

Human  3955 IVGDLAPVNGTSQGKFQGLDLNEELYLGGYPDYGAIPKAGLSSGFIGCVRELRIQGEEIVFHDLN 4019
            |||:|||||||||||||||||||||||||||||.|||||||||||:|||||||||||||||||:|
  Rat  3933 IVGNLAPVNGTSQGKFQGLDLNEELYLGGYPDYRAIPKAGLSSGFVGCVRELRIQGEEIVFHDVN 3997

Human  4020 LTAHGISHCPTCRDRPCQNGGQCHDSESSSYVCVCPAGFTGSRCEHSQALHCHPEACGPDATCVN 4084
            ||.|||||||||:||||||||||||||||||.|||||||||||||||||||||||||||||||||
  Rat  3998 LTTHGISHCPTCQDRPCQNGGQCHDSESSSYTCVCPAGFTGSRCEHSQALHCHPEACGPDATCVN 4062

Human  4085 RPDGRGYTCRCHLGRSGLRCEEGVTVTTPSLSGAGSYLALPALTNTHHELRLDVEFKPLAPDGVL 4149
            |||||||.|||||||||:||||||||||||:|||||||.||||||||||||||||||||.|||:|
  Rat  4063 RPDGRGYNCRCHLGRSGMRCEEGVTVTTPSMSGAGSYLVLPALTNTHHELRLDVEFKPLEPDGIL 4127

Human  4150 LFSGGKSGPVEDFVSLAMVGGHLEFRYELGSGLAVLRSAEPLALGRWHRVSAERLNKDGSLRVNG 4214
            ||||||||||||||||||||||||||||||||||||||.||||||||||||||||||||||:|:|
  Rat  4128 LFSGGKSGPVEDFVSLAMVGGHLEFRYELGSGLAVLRSLEPLALGRWHRVSAERLNKDGSLQVDG 4192

Human  4215 GRPVLRSSPGKSQGLNLHTLLYLGGVEPSVPLSPATNMSAHFRGCVGEVSVNGKRLDLTYSFLGS 4279
            ||||||||||||||||||||||||||||||.||||||||||||||||||||||||||||||||||
  Rat  4193 GRPVLRSSPGKSQGLNLHTLLYLGGVEPSVQLSPATNMSAHFRGCVGEVSVNGKRLDLTYSFLGS 4257

Human  4280 QGIGQCYDSSPCERQPCQHGATCMPAGEYEFQCLCRDGFKGDLCEHEENPCQLREPCLHGGTCQG 4344
            :|:||||||||||||||::||||||||||||||||:|||||||||||||||||:||||:||||:|
  Rat  4258 RGVGQCYDSSPCERQPCRNGATCMPAGEYEFQCLCQDGFKGDLCEHEENPCQLQEPCLNGGTCRG 4322

Human  4345 TRCLCLPGFSGPRCQQGSGHGIAESDWHLEGSGGNDAPGQYGAYFHDDGFLAFPGHVFSRSLPEV 4409
            |||||||||||||||||:|:|:.|||||.||||||||||||||||||:||||.||:.||||||||
  Rat  4323 TRCLCLPGFSGPRCQQGAGYGVVESDWHPEGSGGNDAPGQYGAYFHDNGFLALPGNSFSRSLPEV 4387

Human  4410 PETIELEVRTSTASGLLLWQGVEVGEAGQGKDFISLGLQDGHLVFRYQLGSGEARLVSEDPINDG 4474
            |||||.|||||||:|||||||| |.|:.:.|||||||||||||||.|||||||||||||||||||
  Rat  4388 PETIEFEVRTSTANGLLLWQGV-VKESSRSKDFISLGLQDGHLVFNYQLGSGEARLVSEDPINDG 4451

Human  4475 EWHRVTALREGRRGSIQVDGEELVSGRSPGPNVAVNAKGSVYIGGAPDVATLTGGRFSSGITGCV 4539
            |||||||||||:||||||||||||.|||||||||||.|..:||||||||||||.|:||||||||:
  Rat  4452 EWHRVTALREGQRGSIQVDGEELVIGRSPGPNVAVNTKDIIYIGGAPDVATLTRGKFSSGITGCL 4516

Human  4540 KNLVLHSARPGAPPPQPLDLQHRAQAGANTRPCPS 4574
            |||||||||||||||||||||||||||||||||||
  Rat  4517 KNLVLHSARPGAPPPQPLDLQHRAQAGANTRPCPS 4551

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HSPG2	XP_011539620.1	SEA	80..193	CDD:214554	94/112 (84%)
		LDLa	216..251	CDD:238060	33/34 (97%)
		LDLa	302..336	CDD:238060	29/33 (88%)
		LDLa	342..376	CDD:238060	30/33 (91%)
		LDLa	385..420	CDD:238060	31/34 (91%)
		IG	431..507	CDD:214652	68/75 (91%)
		Ig_Perlecan_D2_like	438..515	CDD:143220	70/76 (92%)
		LamB	608..734	CDD:214597	109/125 (87%)
		EGF_Lam	782..824	CDD:238012	38/41 (93%)
		EGF_Lam	831..888	CDD:238012	55/56 (98%)
		Laminin_EGF	897..939	CDD:278482	32/41 (78%)
		LamB	1003..1130	CDD:214597	106/126 (84%)
		EGF_Lam	1176..1225	CDD:238012	42/48 (88%)
		EGF_Lam	1227..1282	CDD:238012	50/54 (93%)
		Laminin_EGF	1293..1340	CDD:278482	40/46 (87%)
		LamB	1574..1699	CDD:214597	118/124 (95%)
		EGF_Lam	1746..1794	CDD:238012	39/47 (83%)
		Laminin_EGF	1796..1851	CDD:278482	51/54 (94%)
		Ig_2	1866..1958	CDD:290606	79/91 (87%)
		IG_like	1866..1946	CDD:214653	68/79 (86%)
		Ig3_Perlecan_like	1954..2039	CDD:143231	82/84 (98%)
		IG	1961..2040	CDD:214652	76/78 (97%)
		I-set	2049..2133	CDD:254352	70/83 (84%)
		Ig	2063..2133	CDD:299845	57/69 (83%)
		I-set	2139..2225	CDD:254352	77/85 (91%)
		IGc2	2153..2215	CDD:197706	55/61 (90%)
		IG_like	2240..2317	CDD:214653	64/76 (84%)
		IGc2	2247..2307	CDD:197706	49/59 (83%)
		IG	2341..2418	CDD:214652	64/76 (84%)
		IGc2	2348..2408	CDD:197706	52/59 (88%)
		IG_like	2434..2508	CDD:214653	66/73 (90%)
		IGc2	2441..2500	CDD:197706	54/58 (93%)
		IG_like	2530..2607	CDD:214653	64/76 (84%)
		IGc2	2537..2595	CDD:197706	50/57 (88%)
		I-set	2620..2703	CDD:254352	71/82 (87%)
		IGc2	2633..2693	CDD:197706	52/59 (88%)
		IG	2731..2800	CDD:214652	64/68 (94%)
		IGc2	2731..2790	CDD:197706	56/58 (97%)
		IG_like	2819..2896	CDD:214653	64/76 (84%)
		IGc2	2826..2885	CDD:197706	51/58 (88%)
		IG	2916..2993	CDD:214652	68/76 (89%)
		IGc2	2923..2983	CDD:197706	51/59 (86%)
		IG	3016..3093	CDD:214652	68/76 (89%)
		IGc2	3023..3083	CDD:197706	53/59 (90%)
		Ig_2	3112..3192	CDD:290606	60/79 (76%)
		IG_like	3115..3192	CDD:214653	58/76 (76%)
		I-set	3205..3291	CDD:254352	78/85 (92%)
		ig	3209..3289	CDD:278476	72/79 (91%)
		IG	3303..3385	CDD:214652	60/81 (74%)
		Ig	3313..3382	CDD:143165	51/68 (75%)
		IG	3404..3478	CDD:214652	60/73 (82%)
		IGc2	3409..3468	CDD:197706	49/58 (84%)
		I-set	3482..3565	CDD:254352	60/82 (73%)
		IGc2	3496..3555	CDD:197706	41/58 (71%)
		IG_like	3589..3666	CDD:214653	68/76 (89%)
		Ig	3600..3666	CDD:299845	58/65 (89%)
		I-set	3676..3755	CDD:254352	69/78 (88%)
		IGc2	3686..3745	CDD:197706	52/58 (90%)
		I-set	3764..3841	CDD:254352	68/76 (89%)
		Ig	3779..3834	CDD:299845	48/54 (89%)
		LamG	3848..4008	CDD:238058	152/165 (92%)
		EGF_CA	<4035..4064	CDD:238011	27/28 (96%)
		LamG	4117..4266	CDD:238058	141/148 (95%)
		EGF	4291..4321	CDD:278437	26/29 (90%)
EGF_CA	4328..4359	CDD:238011	27/30 (90%)
LamG	4386..4545	CDD:238058	136/158 (86%)
Hspg2	XP_038967228.1	SEA	80..194	CDD:413344	95/113 (84%)
		LDLa	216..251	CDD:238060	33/34 (97%)
		LDLa	301..332	CDD:197566	26/30 (87%)
		LDLa	346..375	CDD:238060	25/28 (89%)
		LDLa	384..419	CDD:238060	31/34 (91%)
		Ig_Perlecan_like	437..514	CDD:143220	70/76 (92%)
		Ig strand B	440..444	CDD:143220	3/3 (100%)
		Ig strand C	453..457	CDD:143220	3/3 (100%)
		Ig strand E	478..482	CDD:143220	3/3 (100%)
		Ig strand F	492..497	CDD:143220	4/4 (100%)
		Ig strand G	506..509	CDD:143220	2/2 (100%)
		LamB	606..732	CDD:214597	109/125 (87%)
		EGF_Lam	780..822	CDD:238012	38/41 (93%)
		EGF_Lam	829..886	CDD:238012	55/56 (98%)
		Laminin_EGF	895..937	CDD:395007	32/41 (78%)
		Laminin_B	1006..1140	CDD:395006	112/133 (84%)
		EGF_Lam	1174..1223	CDD:238012	42/48 (88%)
		EGF_Lam	1224..1280	CDD:238012	50/55 (91%)
		Laminin_EGF	1291..1338	CDD:395007	40/46 (87%)
		Laminin_B	1555..1687	CDD:395006	122/131 (93%)
		EGF_Lam	1722..1770	CDD:238012	39/47 (83%)
		EGF_Lam	1771..1828	CDD:238012	52/56 (93%)
		Ig strand A	1835..1840	CDD:409353	2/4 (50%)
		IG_like	1841..1921	CDD:214653	68/79 (86%)
		Ig strand A'	1843..1847	CDD:409353	2/3 (67%)
		Ig strand B	1850..1860	CDD:409353	8/9 (89%)
		Ig strand C	1865..1872	CDD:409353	6/6 (100%)
		Ig strand C'	1873..1876	CDD:409353	2/2 (100%)
		Ig strand E	1887..1893	CDD:409353	5/5 (100%)
		Ig strand F	1900..1908	CDD:409353	7/7 (100%)
		Ig strand G	1911..1919	CDD:409353	3/7 (43%)
		IgI_Perlecan_like	1929..2014	CDD:409412	82/84 (98%)
		Ig strand B	1947..1951	CDD:409412	3/3 (100%)
		Ig strand C	1961..1965	CDD:409412	3/3 (100%)
		Ig strand E	1981..1985	CDD:409412	3/3 (100%)
		Ig strand F	1995..2000	CDD:409412	4/4 (100%)
		Ig strand G	2008..2011	CDD:409412	2/2 (100%)
		Ig	2024..2108	CDD:416386	70/83 (84%)
		Ig strand A'	2032..2035	CDD:409353	2/2 (100%)
		Ig strand B	2041..2048	CDD:409353	6/6 (100%)
		Ig strand C	2054..2058	CDD:409353	3/3 (100%)
		Ig strand C'	2060..2062	CDD:409353	1/1 (100%)
		Ig strand D	2068..2072	CDD:409353	3/3 (100%)
		Ig strand E	2074..2078	CDD:409353	3/3 (100%)
		Ig strand F	2087..2095	CDD:409353	6/7 (86%)
		Ig strand G	2098..2108	CDD:409353	6/9 (67%)
		I-set	2114..2200	CDD:400151	77/85 (91%)
		Ig strand A'	2122..2126	CDD:409353	3/3 (100%)
		Ig strand B	2129..2139	CDD:409353	9/9 (100%)
		Ig strand C	2144..2150	CDD:409353	4/5 (80%)
		Ig strand C'	2151..2154	CDD:409353	2/2 (100%)
		Ig strand E	2166..2172	CDD:409353	4/5 (80%)
		Ig strand F	2179..2187	CDD:409353	7/7 (100%)
		IG_like	2215..2292	CDD:214653	64/76 (84%)
		Ig strand B	2226..2230	CDD:409353	3/3 (100%)
		Ig strand C	2239..2243	CDD:409353	3/3 (100%)
		Ig strand E	2259..2262	CDD:409353	2/2 (100%)
		Ig strand F	2272..2277	CDD:409353	4/4 (100%)
		Ig strand G	2285..2288	CDD:409353	2/2 (100%)
		IG_like	2316..2389	CDD:214653	62/74 (84%)
		Ig strand B	2327..2331	CDD:409353	3/3 (100%)
		Ig strand C	2338..2342	CDD:409353	3/3 (100%)
		Ig strand F	2371..2376	CDD:409353	4/4 (100%)
		Ig strand G	2382..2385	CDD:409353	0/2 (0%)
Ig	2404..2484	CDD:416386	72/79 (91%)
Ig strand C	2434..2438	CDD:409353	3/3 (100%)
Ig strand E	2453..2457	CDD:409353	3/3 (100%)
Ig strand F	2467..2472	CDD:409353	3/4 (75%)
Ig strand G	2481..2484	CDD:409353	2/2 (100%)
IG_like	2506..2581	CDD:214653	62/74 (84%)
Ig strand C	2530..2534	CDD:409353	3/3 (100%)
Ig strand E	2549..2553	CDD:409353	3/3 (100%)
Ig strand F	2563..2568	CDD:409353	4/4 (100%)
IG	2602..2679	CDD:214652	66/76 (87%)
IG_like	2707..2776	CDD:214653	64/68 (94%)
Ig strand B	2710..2714	CDD:409353	3/3 (100%)
Ig strand C	2722..2727	CDD:409353	4/4 (100%)
Ig strand E	2743..2746	CDD:409353	2/2 (100%)
Ig strand F	2756..2761	CDD:409353	4/4 (100%)
Ig strand G	2769..2772	CDD:409353	2/2 (100%)
IGc2	2802..2861	CDD:197706	51/58 (88%)
Ig strand C	2819..2823	CDD:409353	2/3 (67%)
Ig strand E	2838..2842	CDD:409353	2/3 (67%)
Ig strand F	2852..2857	CDD:409353	4/4 (100%)
IG	2892..2969	CDD:214652	68/76 (89%)
IG_like	2994..3066	CDD:214653	65/71 (92%)
Ig strand B	3000..3004	CDD:409353	3/3 (100%)
Ig strand C	3013..3017	CDD:409353	3/3 (100%)
Ig strand E	3032..3036	CDD:409353	1/3 (33%)
Ig strand F	3046..3051	CDD:409353	4/4 (100%)
Ig strand G	3059..3062	CDD:409353	2/2 (100%)
IG	3087..3165	CDD:214652	58/77 (75%)
Ig	3178..3264	CDD:416386	78/85 (92%)
Ig strand A	3178..3181	CDD:409353	2/2 (100%)
Ig strand A'	3186..3190	CDD:409353	3/3 (100%)
Ig strand B	3195..3202	CDD:409353	6/6 (100%)
Ig strand C	3208..3215	CDD:409353	6/6 (100%)
Ig strand D	3223..3226	CDD:409353	2/2 (100%)
Ig strand E	3230..3236	CDD:409353	4/5 (80%)
Ig strand F	3243..3250	CDD:409353	5/6 (83%)
Ig strand G	3256..3264	CDD:409353	7/7 (100%)
Ig strand A	3267..3270	CDD:409353	2/2 (100%)
IG_like	3276..3357	CDD:214653	60/81 (74%)
Ig strand A'	3276..3279	CDD:409353	2/2 (100%)
Ig strand B	3285..3293	CDD:409353	5/7 (71%)
Ig strand C	3299..3303	CDD:409353	2/3 (67%)
Ig strand C'	3306..3309	CDD:409353	0/2 (0%)
Ig strand D	3315..3319	CDD:409353	1/3 (33%)
Ig strand E	3323..3328	CDD:409353	2/4 (50%)
Ig strand F	3336..3344	CDD:409353	6/7 (86%)
Ig strand G	3347..3357	CDD:409353	8/9 (89%)
Ig_3	3367..3437	CDD:404760	60/69 (87%)
Ig strand A'	3375..3378	CDD:409353	2/2 (100%)
Ig strand B	3384..3391	CDD:409353	5/6 (83%)
Ig strand C	3397..3402	CDD:409353	4/4 (100%)
Ig strand C'	3405..3407	CDD:409353	0/1 (0%)
Ig strand D	3410..3414	CDD:409353	3/3 (100%)
Ig strand E	3416..3420	CDD:409353	2/3 (67%)
Ig strand F	3429..3437	CDD:409353	7/7 (100%)
Ig strand G	3440..3450	CDD:409353	6/9 (67%)
Ig	3454..3537	CDD:416386	60/82 (73%)
Ig strand B	3471..3475	CDD:409353	3/3 (100%)
Ig strand C	3484..3488	CDD:409353	2/3 (67%)
Ig strand F	3517..3522	CDD:409353	4/4 (100%)
Ig	3560..3638	CDD:416386	69/77 (90%)
Ig strand A'	3563..3567	CDD:409353	2/3 (67%)
Ig strand B	3570..3579	CDD:409353	8/8 (100%)
Ig strand C	3585..3590	CDD:409353	3/4 (75%)
Ig strand C'	3593..3596	CDD:409353	2/2 (100%)
Ig strand E	3603..3610	CDD:409353	6/6 (100%)
Ig strand F	3617..3625	CDD:409353	7/7 (100%)
Ig strand G	3628..3638	CDD:409353	7/9 (78%)
Ig	3662..3722	CDD:409353	54/59 (92%)
Ig strand B	3662..3665	CDD:409353	2/2 (100%)
Ig strand C	3674..3678	CDD:409353	3/3 (100%)
Ig strand E	3693..3697	CDD:409353	1/3 (33%)
Ig strand F	3707..3712	CDD:409353	4/4 (100%)
I-set	3731..3813	CDD:400151	72/81 (89%)
Ig strand A	3733..3736	CDD:409353	2/2 (100%)
Ig strand A'	3738..3742	CDD:409353	3/3 (100%)
Ig strand B	3745..3754	CDD:409353	7/8 (88%)
Ig strand C	3760..3765	CDD:409353	2/4 (50%)
Ig strand C'	3768..3772	CDD:409353	2/3 (67%)
Ig strand E	3778..3785	CDD:409353	6/6 (100%)
Ig strand F	3792..3800	CDD:409353	7/7 (100%)
Ig strand G	3803..3813	CDD:409353	8/9 (89%)
LamG	3820..3986	CDD:238058	152/165 (92%)
EGF_CA	4009..4042	CDD:238011	30/32 (94%)
LamG	4095..4244	CDD:238058	141/148 (95%)
EGF	4269..4299	CDD:394967	26/29 (90%)
EGF_CA	4306..4337	CDD:238011	27/30 (90%)
LamG	4364..4522	CDD:238058	136/158 (86%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	319	1.000	Domainoid score	I14424
eggNOG	0	0.000	Not matched by this tool.
HGNC	1	1.500	-	-
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	4415	1.000	Inparanoid score	I162
NCBI	1	1.000	-	-
OMA	1	1.010	-	-		QHG46672
OrthoDB	1	1.010	-	-		D17288at33208
OrthoFinder	1	1.000	-	-		FOG0006846
OrthoInspector	1	1.000	-	-		oto129537
orthoMCL	1	0.900	-	-		OOG6_107789
Panther	1	1.100	-	-	LDO	PTHR10574
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4935
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	14.480