Protein Alignment TBCD and tbcd

DIOPT Version :9

• Sequence 1: NP_608648.1
• Gene: TBCD / 33389
• FlyBaseID: FBgn0027509
• Length: 1189
• Species: Drosophila melanogaster
• Sequence 2: XP_031750025.1
• Gene: tbcd / 779832
• XenbaseID: XB-GENE-493400
• Length: 1184
• Species: Xenopus tropicalis
• Alignment Length: 1204
• Identity: 469/1204 - (38%)
• Similarity: 702/1204 - (58%)
• Gaps: 74/1204 - (6%)

  Fly     6 EECKDEDLPA--NTLEHFTELQQVLEMIDNIKSIAANTFEREF--EQYAQVLSRYQEQPHLLDPH 66
            ||....|:.|  |.||.|.|.|:..::|.:::::......||.  :::..::.:|||||||||||
 Frog     9 EEDGSPDVIASGNILESFMENQETRDLIGSLRTVWQELVSREVCTQRFVVIMDKYQEQPHLLDPH 73

  Fly    67 LEELLGKLLHKIRKPDLDTGELHAAFKYLYIICKVRTYKVLVKFMPHELSDLEFVLDLLGQQNPK 131
            |:.:|..||..|:.........|.|||:||||.|||.||:.::..|||:.|::.||:::..|:||
 Frog    74 LDWMLNSLLEIIQDKASPPVLFHLAFKFLYIISKVRGYKIFLRLFPHEVVDVQPVLEMISAQDPK 138

  Fly   132 EFEQWETRYILLLWMSILVLNPFHMSRLDAYDTSTSAPTTNCSPVNHVQSKNTKMDRIFELIQLY 196
            :.|.|||||:||||:|:..|.||.:||||....|...|           .:...||.|.::.:.|
 Frog   139 DHETWETRYMLLLWLSMTCLIPFDLSRLDGNIASDLGP-----------KRKPTMDIILDVAKSY 192

  Fly   197 VSSNDTCSSMAAFLAAKYFIRSDIKDLYLERFLDWIMEQHQADTL-NVKF----------GQLAA 250
            :..:|.....||.|.:|:..|.|:|...:..||||.:     .|| |..:          |.|.|
 Frog   193 LVVSDKARDAAAVLVSKFITRPDVKQKRMADFLDWTL-----STLSNASYLTMEGTIAMDGMLQA 252

  Fly   251 VAAILKHGKREDLLPYADKLLQWITSCQYKDDNDFLKYKNYVKIIQRIGLVHLKPRIASWRYKRG 315
            :|.:.|||||||.||||..:|..:.:|...|.|..:..|...|::||:||..||.::|:|||:||
 Frog   253 LAQLFKHGKREDCLPYASIVLTCLDNCNLCDSNQTVLRKLGTKLVQRLGLTFLKTKVANWRYQRG 317

  Fly   316 TRSLATNLNQTTA--AGGEPVVLEQSLEEGEEIVVPDAIEEVIEELLQALRSGGNDIRWSAAKGL 378
            :|.||.||.|:::  ....|.:   ..||.|...:|:.||.|:|:||..|:.....:|||||||:
 Frog   318 SRCLAANLLQSSSDTQKSNPAL---PGEEEEAYDIPEEIENVVEQLLVGLKDKDTIVRWSAAKGI 379

  Fly   379 GRVTNRLPKELADEVIGSVIDILNPLEPHEAWHGACLALAELAKRGLLLPHRLEELVPLLMQALF 443
            ||:|.||||||||:|:|||:|..:..|.:.||||.|||||||.:||||||.||.::|||:::||.
 Frog   380 GRLTGRLPKELADDVVGSVLDCFSFQETNNAWHGGCLALAELGRRGLLLPSRLPDVVPLILKALV 444

  Fly   444 YDEMKGYMSVGQHIRDSACYMCWAFARAYNPDDVKPFVHKISSGLLTVAVFDREVNCRRAASAAF 508
            |||.:|..|||.::||:|||:||||||||:|.::.|||::|:|.|:..|||||:|||||||||||
 Frog   445 YDEKRGACSVGSNVRDAACYVCWAFARAYDPQEMNPFVNEIASALVIAAVFDRDVNCRRAASAAF 509

  Fly   509 QESVGRLGNFPFGIEISTTTDFYSVGIRQNSYLNISDYIAQFEVYREPLINHLVQHKVSHWDSAI 573
            ||:|||.|.||.||:|.||.|:::||.|.|.|||||.::|.|..|.:|:|:|||:.|::|||..:
 Frog   510 QENVGRQGTFPHGIDILTTADYFAVGNRANCYLNISVFVAGFPEYTKPMIDHLVEMKINHWDGVV 574

  Fly   574 RELTAKALHKLSLWEPEYMAAVVLPQLLAKTDTIDINCRHGCVLAMGEITLTLRKLEEKSD-PQV 637
            |||:.||||.|:...|:||...|||:||......|::.|||.:||..|||..:.||..:.: |..
 Frog   575 RELSTKALHNLTPTAPQYMTETVLPRLLPLAIGTDLHTRHGAILACAEITHAVYKLSAQCNRPLS 639

  Fly   638 VYLSNQRVAELNELIITFLDKNFYRGMSGDLMKSCTSSYIKNCSLAKLQATPECLV-SWQKVIDS 701
            .||:|:.:|.|..:.....::..|||:.|:||:......::..||::.....|.:: .|..:|.:
 Frog   640 DYLNNETLAGLAAIHPKLQERQLYRGLGGELMRPAVCCLVEKLSLSQFPHPGEDIIGGWLWLITN 704

  Fly   702 CL-------ITKSNAIRDGAVEAFGELCTTYYCSDSRHGENEAIINTYLTGADNDLEEHIRMGYI 759
            .|       .|....|::.||.|...||..||...:....::.:  ...|......||.:|.|:.
 Frog   705 SLKSLHLFSSTARQKIKEAAVSALSTLCQEYYKGRAAAAHDDLV--KQFTSELQSSEEMVRCGFS 767

  Fly   760 AALGVLPSFMIRCHLQAILDSLVKHSLTPLQAVLVGEMGDRENIQAYRWSEARTQSVLALTKLVK 824
            .|||.||.|:::..||.:|..|  ..:|.:....||            ::|:|..::.|:.::.:
 Frog   768 LALGALPQFLLKGRLQQVLGGL--RRVTSISGKDVG------------FAESRRDALRAIAQVCQ 818

  Fly   825 TVGY--GGGIDSFAEPKNFNKVIECLLRALQEYTLDNRGDIGAWVREAAMSSLYEI---VTTCPP 884
            |||.  .|..:.....:|...|...||..:.:||.|:|||:|||||||||:||.::   |.....
 Frog   819 TVGVRAEGSAEEAVCRENMALVYNTLLNCMNDYTTDSRGDVGAWVREAAMASLQDVTLLVAQTEA 883

  Fly   885 DLLAPEQVHEIVVGFMQQAVEKIDRTRGLGGRLCCQLIH-HQPRIPYIREHSKLLEIFP-ADADS 947
            |||.|:.|..::....||:.|||||.|...|.:...|:: ..|.:|::....:|..||| ..|:|
 Frog   884 DLLDPDFVQRMMCALSQQSAEKIDRYRAFAGSVFLNLLYFSDPPVPHVPHREELERIFPRTQAES 948

  Fly   948 VLWLFADHTFPLFCELLSLPDYSKRVLLGLSASIGQLTESLIKYASSALFHFLR---SNPETVPR 1009
            :.|......||...:||.|..|...||:||:.|:|.||||.::|::..||.:||   ::.|.:..
 Frog   949 LNWNAPSQAFPRITQLLGLATYRYYVLMGLTVSVGGLTESTVRYSAQGLFEYLRAIQNDTEQMDA 1013

  Fly  1010 LCSEVVQIFEEHLLNERVTYPLLSFLDILIGSGTVESVLHDEANPFAEDIFRLLNLEVKGYKKLY 1074
            ..:.::|:|.::...:||:.|||..||.::.:|..:....:|.:|||.|:..|...|:|..|.:.
 Frog  1014 FSASLLQVFRDNQHIDRVSIPLLKMLDQMLANGCFDIYTQEENHPFASDLLSLCREEIKRSKDIQ 1078

  Fly  1075 KTATSISAFCQLLQVP-RLSKRILSKLSVFLGLQHVHVRKTAATKLYEALALHGDVTEVPEENMD 1138
            |..:||:.||.|:|.| .:.|::|.:|.:.:......:|||.|:::||.|..:.||.|  .|.:|
 Frog  1079 KLRSSIAVFCGLIQFPGDIRKKVLFQLLLLVCHPFPRIRKTTASEVYEMLLTYDDVVE--PEILD 1141

  Fly  1139 EILTLLSETDWTQPLVEVRPLRNQLCQLMDIKPP 1172
            |::.:||::.|...|..||..||.||.|:.:..|
 Frog  1142 EVMAVLSDSTWDADLPTVREQRNHLCDLLKVPRP 1175

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBCD	NP_608648.1	TFCD_C	24..>584	CDD:303064	265/574 (46%)
		HEAT repeat	355..383	CDD:293787	14/27 (52%)
		HEAT repeat	393..423	CDD:293787	17/29 (59%)
		TFCD_C	890..1075	CDD:289385	61/189 (32%)
tbcd	XP_031750025.1	TFCD_C	47..981	CDD:418705	391/968 (40%)
		TFCD_C	894..1079	CDD:403718	60/184 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	653	1.000	Domainoid score	I155
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H4368
Inparanoid	1	1.050	824	1.000	Inparanoid score	I456
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D79003at2759
OrthoFinder	1	1.000	-	-		FOG0004779
OrthoInspector	1	1.000	-	-		oto105099
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3933
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	8.060