DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment GlyP and PHS1

DIOPT Version :9

Sequence 1:	NP_001027219.1	Gene:	GlyP / 33386	FlyBaseID:	FBgn0004507	Length:	844	Species:	Drosophila melanogaster
Sequence 2:	NP_189578.1	Gene:	PHS1 / 822590	AraportID:	AT3G29320	Length:	962	Species:	Arabidopsis thaliana

Alignment Length:	915	Identity:	378/915 - (41%)
Similarity:	553/915 - (60%)	Gaps:	96/915 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SKPQ---SDA--DRRKQISVRGIAEVG-NVTEVKKNFNRHLHYTLVKDRNVSTLRDYYFALANTV 60
            |:|:   :||  |..:::.:..:.... :...|..:...|..:|.:.......|...:||.|.:|
plant    64 SEPKAKVTDAVLDSEQEVFISSMNPFAPDAASVASSIKYHAEFTPLFSPEKFELPKAFFATAQSV 128

  Fly    61 KDNMVGRWIRTQQHYYEKDPKRVYYLSLEYYMGRSLTNTMINLGIQSECEEAMYQLGLDIENLEE 125
            :|.::..|..|.::|...:.|:.||||:|:..||:|:|.:.|||:.|...:|:.:||.|:|::..
plant   129 RDALIMNWNATYEYYNRVNVKQAYYLSMEFLQGRALSNAVGNLGLNSAYGDALKRLGFDLESVAS 193

  Fly   126 MEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEYGIFAQKIKNGEQVEEPDDWLRYGNPW 190
            .|.|..||||||||||:|||||||||...|:|||:||:||:|.|:|....|.|..:|||...|||
plant   194 QEPDPALGNGGLGRLASCFLDSMATLNYPAWGYGLRYKYGLFKQRITKDGQEEAAEDWLELSNPW 258

  Fly   191 EKARPEFMLPVNFYGRVIDTPEGKK-WVDTQRVFAMPYDNPIPGYNNNHVNTLRLWSAKSPI-DF 253
            |..|.:...|:.|||:|:...:||| |:..:.:.|:.||.|||||.......|||||.|:|. ||
plant   259 EIVRNDVSYPIKFYGKVVFGSDGKKRWIGGEDIVAVAYDVPIPGYKTKTTINLRLWSTKAPSEDF 323

  Fly   254 NLKFFNDGDYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFMCAATLQDIIRRYKASKFG 318
            :|..:|.|.:.:|......||.|..||||.|...|||.|||||:|.:|:|:||||:.|     |.
plant   324 DLSSYNSGKHTEAAEALFNAEKICFVLYPGDESTEGKALRLKQQYTLCSASLQDIVAR-----FE 383

  Fly   319 SREAVRNTFDHFPDKVAIQLNDTHPSLAIPELMRILVDEEHLTWEKAWDITVRSCAYTNHTVLPE 383
            :|......::.||:|||:|:|||||:|.||||||||:|.:.|:||.||.||.|:.||||||||||
plant   384 TRSGGNVNWEEFPEKVAVQMNDTHPTLCIPELMRILMDLKGLSWEDAWKITQRTVAYTNHTVLPE 448

  Fly   384 ALERWPVSLLESILPRHLQIIYHINFLHMENVKKKF----PDDLDR----MRRMSMV-------- 432
            |||:|.:.|:|.:||||::||..|:...:..:..::    ||.|:.    ||.:..|
plant   449 ALEKWSLELMEKLLPRHVEIIEKIDEELVRTIVSEYGTADPDLLEEKLKAMRILENVELPSAFAD 513

  Fly   433 -------------------------------EEDGE----------KRINMAHLSIVGSHAVNGV 456
                                           ||:.|          |.:.||:|::||.||||||
plant   514 VIVKPVNKPVTAKDAQNGVKTEQEEEKTAGEEEEDEVIPEPTVEPPKMVRMANLAVVGGHAVNGV 578

  Fly   457 AAIHSQILKDSLFHDFYEMEPQKFQNKTNGITPRRWLLLCNPGLSDLIAEKIG-DEWPVHLDQLV 520
            |.|||:|:|..:|:||.::.|:||||||||:|||||:..|||.|||:|...|| ::|.::.:::.
plant   579 AEIHSEIVKQDVFNDFVQLWPEKFQNKTNGVTPRRWIRFCNPYLSDIITNWIGTEDWVLNTEKVA 643

  Fly   521 ALKKWAKDPNFQRNVARVKQENKLKLAAILEKDYGVKINPSSMFDIQVKRIHEYKRQLLNCLHII 585
            .|:|:|.:.:.|......|::||||:.:::::..|..::|.:|||||:||||||||||||.|.|:
plant   644 ELRKFADNEDLQSEWRAAKKKNKLKVVSLIKERTGYTVSPDAMFDIQIKRIHEYKRQLLNILGIV 708

  Fly   586 TLYNRIKKDPTAN----FTPRTIMIGGKAAPGYYVAKQIIKLICAVGNVVNNDPIVGDKLKVIFL 646
            ..|.::|:...:.    |.||..:.||||...|..||:|:|.|..|.:.:|:||.:||.|||||:
plant   709 YRYKKMKEMSASEREKAFVPRVCIFGGKAFATYVQAKRIVKFITDVASTINHDPEIGDLLKVIFV 773

  Fly   647 ENYRVTLAEKIMPAADLSEQISTAGTEASGTGNMKFQLNGALTIGTLDGANVEMAEEMGLDNIFI 711
            .:|.|::||.::||::||:.|||||.|||||.||||.:||.:.||||||||||:.||:|.:|.|:
plant   774 PDYNVSVAELLIPASELSQHISTAGMEASGTSNMKFSMNGCVLIGTLDGANVEIREEVGEENFFL 838

  Fly   712 FGMTVDEVEALKKKGYNAYDYYNANPEVKQVIDQIQGGFFSPGNPNEFKNIADILL--------- 767
            ||...|::..|:|:  .|...:..:|..::|...:..|.|.       .|..|.|:
plant   839 FGAKADQIVNLRKE--RAEGKFVPDPTFEEVKKFVGSGVFG-------SNSYDELIGSLEGNEGF 894

  Fly   768 -KYDHYYLLADYDAYIKAQDLVSKTYQNQAKWLEMSINNIASSGKFSSDRTIAEYAREIWGVEPT 831
             :.|::.:..|:.:||:.|:.|.:.|::|.:|..|||.|.|.|.||||||||.|||::||.::..
plant   895 GRADYFLVGKDFPSYIECQEKVDEAYRDQKRWTRMSIMNTAGSFKFSSDRTIHEYAKDIWNIKQV 959

  Fly   832 WEKLP 836
              :||
plant   960 --ELP 962

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GlyP	NP_001027219.1	GT1_Glycogen_Phosphorylase	29..828	CDD:99996	370/872 (42%)
GlyP	NP_001027219.1	P_ylase	32..828	CDD:273967	370/869 (43%)
PHS1	NP_189578.1	GT1_Glycogen_Phosphorylase	97..956	CDD:99996	370/872 (42%)
PHS1	NP_189578.1	P_ylase	100..956	CDD:273967	370/869 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	659	1.000	Domainoid score	I23
eggNOG	1	0.900	-	-		E1_COG0058
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	719	1.000	Inparanoid score	I120
OMA	1	1.010	-	-		QHG62832
OrthoDB	1	1.010	-	-		D240595at2759
OrthoFinder	1	1.000	-	-		FOG0000986
OrthoInspector	1	1.000	-	-		otm3384
orthoMCL	1	0.900	-	-		OOG6_100699
Panther	1	1.100	-	-	O	PTHR11468
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X645
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.840