DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment GlyP and pygb

DIOPT Version :9

Sequence 1:	NP_001027219.1	Gene:	GlyP / 33386	FlyBaseID:	FBgn0004507	Length:	844	Species:	Drosophila melanogaster
Sequence 2:	XP_031756561.1	Gene:	pygb / 100491051	XenbaseID:	XB-GENE-966439	Length:	843	Species:	Xenopus tropicalis

Alignment Length:	839	Identity:	606/839 - (72%)
Similarity:	723/839 - (86%)	Gaps:	0/839 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSKPQSDADRRKQISVRGIAEVGNVTEVKKNFNRHLHYTLVKDRNVSTLRDYYFALANTVKDNMV 65
            ||:|.:|.::||||||||:|...||:::|||||||||:||||||||:..|||||||||||:|::|
Frog     1 MSRPLTDQEKRKQISVRGLAGAENVSDLKKNFNRHLHFTLVKDRNVALPRDYYFALANTVRDHLV 65

  Fly    66 GRWIRTQQHYYEKDPKRVYYLSLEYYMGRSLTNTMINLGIQSECEEAMYQLGLDIENLEEMEEDA 130
            ||||||||||||.||||:||||||:||||:|.|||:|||:::.|:||.||||||:|:|||:||||
Frog    66 GRWIRTQQHYYEHDPKRIYYLSLEFYMGRTLQNTMVNLGLENACDEAAYQLGLDMEDLEEIEEDA 130

  Fly   131 GLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEYGIFAQKIKNGEQVEEPDDWLRYGNPWEKARP 195
            ||||||||||||||||||||:||||||||||||:|||.|||.||.||||.|||||||||||||||
Frog   131 GLGNGGLGRLAACFLDSMATIGLAAYGYGIRYEFGIFNQKIANGWQVEEADDWLRYGNPWEKARP 195

  Fly   196 EFMLPVNFYGRVIDTPEGKKWVDTQRVFAMPYDNPIPGYNNNHVNTLRLWSAKSPIDFNLKFFND 260
            |:||||.|:|||..||.|.:|||||.|.|:|||.|:|||.||.|||:||||||:|.:||||.||.
Frog   196 EYMLPVQFFGRVQHTPNGAEWVDTQVVLALPYDTPVPGYKNNTVNTMRLWSAKAPNEFNLKDFNV 260

  Fly   261 GDYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFMCAATLQDIIRRYKASKFGSREAVRN 325
            |.|||||||||||||||||||||||||||||||||||||:.||||||||||:|:||||.|:|||.
Frog   261 GGYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKSSKFGCRDAVRT 325

  Fly   326 TFDHFPDKVAIQLNDTHPSLAIPELMRILVDEEHLTWEKAWDITVRSCAYTNHTVLPEALERWPV 390
            :||.|||||||||||||||:|||||||||||.|.|.|:||||:|||:||||||||||||||||||
Frog   326 SFDAFPDKVAIQLNDTHPSMAIPELMRILVDIEKLEWDKAWDVTVRTCAYTNHTVLPEALERWPV 390

  Fly   391 SLLESILPRHLQIIYHINFLHMENVKKKFPDDLDRMRRMSMVEEDGEKRINMAHLSIVGSHAVNG 455
            .|::::|||||.||:.||..|:..|...||.|:|||||||:|||...||||||||.|||||||||
Frog   391 HLIQNLLPRHLDIIFEINQRHLNRVSSMFPGDVDRMRRMSLVEEGSVKRINMAHLCIVGSHAVNG 455

  Fly   456 VAAIHSQILKDSLFHDFYEMEPQKFQNKTNGITPRRWLLLCNPGLSDLIAEKIGDEWPVHLDQLV 520
            ||.|||.|::|::|||||||:|.|||||||||||||||:||||||:::|||:||:::..:||.|.
Frog   456 VAQIHSDIIRDTVFHDFYEMDPHKFQNKTNGITPRRWLVLCNPGLAEIIAERIGEDYITNLDNLK 520

  Fly   521 ALKKWAKDPNFQRNVARVKQENKLKLAAILEKDYGVKINPSSMFDIQVKRIHEYKRQLLNCLHII 585
            .|..:..|..|.|:||:||||||||.:..||..|.|||||:||||:.||||||||||||||||:|
Frog   521 KLLNFINDEGFIRDVAKVKQENKLKFSRYLESQYKVKINPNSMFDVHVKRIHEYKRQLLNCLHVI 585

  Fly   586 TLYNRIKKDPTANFTPRTIMIGGKAAPGYYVAKQIIKLICAVGNVVNNDPIVGDKLKVIFLENYR 650
            ||||||||||:..:.|||:||||||||||::||.|||||.:||:::||||::||:||.|||||||
Frog   586 TLYNRIKKDPSKQYVPRTVMIGGKAAPGYHMAKMIIKLITSVGDIINNDPVIGDRLKFIFLENYR 650

  Fly   651 VTLAEKIMPAADLSEQISTAGTEASGTGNMKFQLNGALTIGTLDGANVEMAEEMGLDNIFIFGMT 715
            |:||||::||||||||||||||||||||||||.|||||||||:||||||||||.|.:|:|||||.
Frog   651 VSLAEKVVPAADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENLFIFGMR 715

  Fly   716 VDEVEALKKKGYNAYDYYNANPEVKQVIDQIQGGFFSPGNPNEFKNIADILLKYDHYYLLADYDA 780
            |.:||.:.::||||..||...||::|||||:..|:|||..|:.||::.::|:.:|.:.:.|||:.
Frog   716 VPDVERMDREGYNARAYYERIPELRQVIDQLNSGYFSPKQPDLFKDVVNMLMNHDRFKVFADYED 780

  Fly   781 YIKAQDLVSKTYQNQAKWLEMSINNIASSGKFSSDRTIAEYAREIWGVEPTWEKLPAPE 839
            |||:|:.|:..|:|..:|....|:|||.|||||||||||:||||||||||...|:|.|:
Frog   781 YIKSQEKVNALYKNPKEWTRKVIHNIAGSGKFSSDRTIAQYAREIWGVEPGTMKIPPPD 839

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GlyP	NP_001027219.1	GT1_Glycogen_Phosphorylase	29..828	CDD:99996	584/798 (73%)
GlyP	NP_001027219.1	P_ylase	32..828	CDD:273967	581/795 (73%)
pygb	XP_031756561.1	GT35_Glycogen_Phosphorylase	29..828	CDD:340853	584/798 (73%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	1088	1.000	Domainoid score	I24
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H2145
Inparanoid	1	1.050	1282	1.000	Inparanoid score	I167
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D108256at33208
OrthoFinder	1	1.000	-	-		FOG0000986
OrthoInspector	1	1.000	-	-		otm49182
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X645
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	8.060