DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4259 and prss60.1

DIOPT Version :9

Sequence 1:	NP_001259904.1	Gene:	CG4259 / 33385	FlyBaseID:	FBgn0031389	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	NP_001082915.1	Gene:	prss60.1 / 799770	ZFINID:	ZDB-GENE-070424-25	Length:	387	Species:	Danio rerio

Alignment Length:	236	Identity:	72/236 - (30%)
Similarity:	105/236 - (44%)	Gaps:	30/236 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 TFPWVVSVLDQRDWLFRYIGVGSLINPNVVLTAAHILNGTTKYDLVVRAGEWDTSTTADQQHVDL 102
            ::||.|| |....:...:.| |||||...||||||.|...|...|:|..|:    ||  ||.|:.
Zfish    44 SWPWQVS-LHSPIYGGHFCG-GSLINSEWVLTAAHCLPRITTSSLLVFLGK----TT--QQGVNT 100

  Fly   103 EVLN-----IVSHEQFNRFNAENNMALLILVSAFEMTANINLIPLYLQEAGIQKG-SCFFNGWGK 161
            ..:|     |..|..:|....||::|||.|.||...:..|..:.|..|.:....| |.:..|||.
Zfish   101 YEINRTVSVITVHPSYNNLTNENDIALLHLSSAVTFSNYIRPVCLAAQNSVFPNGTSSWITGWGN 165

  Fly   162 VYLN-STDYPTVLKTVQVDLLSMGMCS----SRKLPIQQICGKGLEG--IDCSGDGGAPLV---C 216
            :.|. :...|.:|:...:.::....|:    |..:....||...|:|  ..|.||.|.|:|   |
Zfish   166 IQLGVNLPAPGILQETMIPVVPNDQCNALLGSGSVTNNMICAGLLQGGRDTCQGDSGGPMVSKQC 230

  Fly   217 RILTYPYKYAQVGIVNWLSQKPVENTFIVFTNVAGLLPWID 257
            .:      :.|.||.:|........:..|:|.|:....||:
Zfish   231 LV------WVQSGITSWGYGCADPYSPGVYTRVSQYQSWIN 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4259	NP_001259904.1	Tryp_SPc	39..259	CDD:238113	72/235 (31%)
CG4259	NP_001259904.1	Tryp_SPc	39..256	CDD:214473	70/232 (30%)
prss60.1	NP_001082915.1	Tryp_SPc	33..264	CDD:214473	70/233 (30%)
		Tryp_SPc	34..267	CDD:238113	72/236 (31%)
		Somatomedin_B	349..382	CDD:295334
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587585
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840