DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4259 and f7

DIOPT Version :9

Sequence 1:	NP_001259904.1	Gene:	CG4259 / 33385	FlyBaseID:	FBgn0031389	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	NP_001072819.1	Gene:	f7 / 780280	XenbaseID:	XB-GENE-5787186	Length:	452	Species:	Xenopus tropicalis

Alignment Length:	249	Identity:	69/249 - (27%)
Similarity:	108/249 - (43%)	Gaps:	25/249 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 NYNQIRRETYGSN-PRATFPWVVSVLDQRDWLFRYIGVGSLINPNVVLTAAHILNGTTKYDLVVR 85
            |.|:..|...|.. |:...||...::...    .:|..|:||.||.|:||||.|....:..|.|.
Frog   205 NVNKRARIVGGDMCPKGECPWQALLMYNE----IFICGGTLIAPNWVITAAHCLKPLPENKLTVV 265

  Fly    86 AGEWDTSTTADQQHVDLEVLNIVSHEQF--NRFNAENNMALLILVSAFEMTANINLIPLYLQEA- 147
            .||....|....:. :.:|..|:.||.:  ::.|.:|::|||.|.:....|..:  :||.|.|.
Frog   266 LGEHRIGTPEGTEQ-ESKVSKIIMHEHYYGSKTNNDNDIALLKLTTPVNYTDYV--VPLCLPEKQ 327

  Fly   148 -GIQK----GSCFFNGWGKVYLNSTDYPTVLKTVQVDLLSMGMC-SSRKLPIQQ--ICGKGLEGI 204
             .:|:    .....:|||:: |.|...|.:|:.||:..:....| ...::.|.|  .|....:|.
Frog   328 FAVQELLSIRYSTVSGWGRL-LESGATPELLQRVQLPRVKTQDCIRQTQMNISQNMFCAGYTDGS 391

  Fly   205 --DCSGDGGAPLVCRILTYPYKYAQVGIVNWLSQKPVENTFIVFTNVAGLLPWI 256
              .|.||.|.|   ....|...:...|||:|......:..:.|:|.|:....||
Frog   392 KDSCKGDSGGP---HATQYKNTHFLTGIVSWGLGCAKKEKYGVYTRVSRYTEWI 442

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4259	NP_001259904.1	Tryp_SPc	39..259	CDD:238113	64/231 (28%)
CG4259	NP_001259904.1	Tryp_SPc	39..256	CDD:214473	62/229 (27%)
f7	NP_001072819.1	Gla	67..107	CDD:366184
		EGF_CA	108..144	CDD:238011
		FXa_inhibition	153..189	CDD:373209
		Tryp_SPc	212..445	CDD:238113	66/242 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910