DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG4259 and CELA2A

DIOPT Version :9

Sequence 1:NP_001259904.1 Gene:CG4259 / 33385 FlyBaseID:FBgn0031389 Length:270 Species:Drosophila melanogaster
Sequence 2:NP_254275.1 Gene:CELA2A / 63036 HGNCID:24609 Length:269 Species:Homo sapiens


Alignment Length:280 Identity:77/280 - (27%)
Similarity:126/280 - (45%) Gaps:53/280 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly     8 LTTLI---ISLVNSQYFNYNQIRRETYGSNPRA-TFPWVVSVLDQRDWLFRYIGVGSLINPNVVL 68
            |:||:   :|..:..|..|  :.|...|...|. ::||.||:....:..:.:...||||..:.||
Human     7 LSTLVAGALSCGDPTYPPY--VTRVVGGEEARPNSWPWQVSLQYSSNGKWYHTCGGSLIANSWVL 69

  Fly    69 TAAHILN-------GTTKYDLVVRAGEWDTSTTADQQHVDLEVLNIVSHEQF--NRFNAENNMAL 124
            ||||.::       |..:::|.|          |:...:.:.|..||.|:.:  |:.:..|::||
Human    70 TAAHCISSSRTYRVGLGRHNLYV----------AESGSLAVSVSKIVVHKDWNSNQISKGNDIAL 124

  Fly   125 LILVSAFEMTANINLIPLYLQEAGI---QKGSCFFNGWGKVYLNSTDYPTVLKTVQVDLLSMGMC 186
            |.|.:...:|..|.|  ..|..||.   ....|:..|||::..|.. .|.||:..::.::....|
Human   125 LKLANPVSLTDKIQL--ACLPPAGTILPNNYPCYVTGWGRLQTNGA-VPDVLQQGRLLVVDYATC 186

  Fly   187 SS-----RKLPIQQICGKGLEGI--DCSGDGGAPLVCRILTYPYKYAQVGIVNWLSQ-------K 237
            ||     ..:....||..| :|:  .|:||.|.||.|:  ....::...|||::.|:       |
Human   187 SSSAWWGSSVKTSMICAGG-DGVISSCNGDSGGPLNCQ--ASDGRWQVHGIVSFGSRLGCNYYHK 248

  Fly   238 PVENTFIVFTNVAGLLPWID 257
            |     .|||.|:..:.||:
Human   249 P-----SVFTRVSNYIDWIN 263

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4259NP_001259904.1 Tryp_SPc 39..259 CDD:238113 68/245 (28%)
Tryp_SPc 39..256 CDD:214473 66/242 (27%)
CELA2ANP_254275.1 Tryp_SPc 29..265 CDD:238113 70/256 (27%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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