DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4259 and tmprss5

DIOPT Version :9

Sequence 1:	NP_001259904.1	Gene:	CG4259 / 33385	FlyBaseID:	FBgn0031389	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	XP_009289870.1	Gene:	tmprss5 / 569688	ZFINID:	ZDB-GENE-131121-184	Length:	551	Species:	Danio rerio

Alignment Length:	232	Identity:	66/232 - (28%)
Similarity:	108/232 - (46%)	Gaps:	24/232 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 FPWVVSVLDQRDWLFRYIGVGSLINPNVVLTAAHILNGTTKYDL------VVRAGEWDTSTTADQ 97
            :||.||:....    |:|..||:|....::||||.::   .|.|      ||.||...::.....
Zfish   323 WPWQVSLYYNN----RHICGGSIITNQWIVTAAHCVH---NYRLPQVPSWVVYAGIITSNLAKLA 380

  Fly    98 QHVDLEVLNIVSHEQFNRFNAENNMALLILVSAFEMTANINLIPLYLQEAGIQKGS-CFFNGWGK 161
            |:....|..|:.::.:|....:|::||:.|.:....:..|..:.|...:..:..|: |:.:|||.
Zfish   381 QYQGFAVERIIYNKNYNHRTHDNDIALVKLKTPLNFSDTIRPVCLPQYDHDLPGGTQCWISGWGY 445

  Fly   162 VYLNSTDYPTVLKTVQVDLLSMGMCSSR-----KLPIQQICGKGLEG-ID-CSGDGGAPLVCRIL 219
            ...:....|.|||...|.|:|...|:|.     ::..:.:|....|| :| |.||.|.||||:..
Zfish   446 TQPDDVLIPEVLKEAPVPLISTKKCNSSCMYNGEITSRMLCAGYSEGKVDACQGDSGGPLVCQDE 510

  Fly   220 TYPYKYAQVGIVNWLSQKPVENTFIVFTNVAGLLPWI 256
            ..   :..||:|:|.:.....|...|::.||..|.||
Zfish   511 NV---WRLVGVVSWGTGCAEPNHPGVYSKVAEFLGWI 544

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4259	NP_001259904.1	Tryp_SPc	39..259	CDD:238113	66/232 (28%)
CG4259	NP_001259904.1	Tryp_SPc	39..256	CDD:214473	64/230 (28%)
tmprss5	XP_009289870.1	SRCR_2	211..306	CDD:292133
		Tryp_SPc	311..544	CDD:214473	64/230 (28%)
		Tryp_SPc	312..547	CDD:238113	66/232 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910