DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4259 and tmprss13a

DIOPT Version :9

Sequence 1:	NP_001259904.1	Gene:	CG4259 / 33385	FlyBaseID:	FBgn0031389	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	NP_001152984.1	Gene:	tmprss13a / 559754	ZFINID:	ZDB-GENE-090309-3	Length:	506	Species:	Danio rerio

Alignment Length:	239	Identity:	67/239 - (28%)
Similarity:	110/239 - (46%)	Gaps:	42/239 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 FPWVVSVLDQRDWLFRYIGVGSLINPNVVLTAAHILNG---TTKYDLVVRAGEWDTSTTADQQHV 100
            :||.||:...:    .::..|:||:|:.:::|||...|   .:.|.||...       ...||.:
Zfish   280 YPWQVSLHYNK----AHVCGGTLISPDFIVSAAHCFQGKMANSAYWLVYVG-------IVSQQSL 333

  Fly   101 DLEVL--NIVSHEQFNRFNAENNMALLILVS--AFEMTANINLIPLYLQ--EAGIQKGSCFFNGW 159
            .:..|  .|:..|::|....:|::|||||..  ||..|.....:|.:.|  ..|:|   |:.:|:
Zfish   334 GMPYLVKKIIVSEKYNSDTNDNDVALLILSRPVAFSYTTQPVCLPTFNQTFSGGLQ---CWTSGF 395

  Fly   160 GKVYLNSTDYPTVLKTVQVDLLSMGMCSSRK-----LPIQQICGKGLEG--IDCSGDGGAPLVCR 217
            |.....:....:.|.:|.|:::...:|:|.:     :....||...|:|  ..|.||.|.||||:
Zfish   396 GTTKQGADRASSSLMSVSVNIIDSSVCNSCQIYCGLITNNMICAGDLKGGRDSCQGDSGGPLVCK 460

  Fly   218 ILTYPYKYAQVGIVNW-----LSQKPVENTFIVFTNVAGLLPWI 256
              ....::..|||.:|     ..|||.     |::.|...||||
Zfish   461 --DDNNRWYLVGITSWGAGCGQKQKPG-----VYSRVTSFLPWI 497

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4259	NP_001259904.1	Tryp_SPc	39..259	CDD:238113	67/239 (28%)
CG4259	NP_001259904.1	Tryp_SPc	39..256	CDD:214473	65/237 (27%)
tmprss13a	NP_001152984.1	SRCR_2	178..261	CDD:295335
		Tryp_SPc	268..497	CDD:214473	65/237 (27%)
		Tryp_SPc	269..497	CDD:238113	65/237 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910