DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4259 and prss60.2

DIOPT Version :9

Sequence 1:	NP_001259904.1	Gene:	CG4259 / 33385	FlyBaseID:	FBgn0031389	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	NP_001099071.1	Gene:	prss60.2 / 541408	ZFINID:	ZDB-GENE-050320-109	Length:	328	Species:	Danio rerio

Alignment Length:	233	Identity:	72/233 - (30%)
Similarity:	103/233 - (44%)	Gaps:	20/233 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 PRATFPWVVSVLDQRDWLFRYIG---VGSLINPNVVLTAAHILNGTTKYDLVVRAGEWDTSTTAD 96
            |..::||.||:...     ||.|   .||||:...||||||.|.|.::..|||..|. .|....:
Zfish    41 PEGSWPWQVSLQSP-----RYGGHFCGGSLISSEWVLTAAHCLPGVSESSLVVYLGR-RTQQGVN 99

  Fly    97 QQHVDLEVLNIVSHEQFNRFNAENNMALLILVSAFEMTANINLIPLYLQEAGIQKG-SCFFNGWG 160
            .......|..|:.|..:|....:|::|||.|.||......|..:.|..|.:....| |.:..|||
Zfish   100 THETSRNVAKIIVHSSYNSNTNDNDIALLRLSSAVTFNDYIRPVCLAAQNSVYSAGTSSWITGWG 164

  Fly   161 KVYLN-STDYPTVLKTVQVDLLSMGMCS----SRKLPIQQIC-GKGLEGID-CSGDGGAPLVCRI 218
            .|... :...|.:|:...:.:::...|:    |..:....|| |....|.| |.||.|.|:|.|:
Zfish   165 DVQAGVNLPAPGILQETMIPVVANDRCNAQLGSGTVTNNMICAGLAKGGKDTCQGDSGGPMVTRL 229

  Fly   219 LTYPYKYAQVGIVNWLSQKPVENTFIVFTNVAGLLPWI 256
            .|.   :.|.||.:|.......|:..|:|.|:....||
Zfish   230 CTV---WIQAGITSWGYGCADPNSPGVYTRVSQYQSWI 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4259	NP_001259904.1	Tryp_SPc	39..259	CDD:238113	71/229 (31%)
CG4259	NP_001259904.1	Tryp_SPc	39..256	CDD:214473	69/227 (30%)
prss60.2	NP_001099071.1	Tryp_SPc	33..264	CDD:214473	70/231 (30%)
		Tryp_SPc	34..267	CDD:238113	72/233 (31%)
		Somatomedin_B	296..326	CDD:295334
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587583
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840