DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4259 and prss27

DIOPT Version :9

Sequence 1:	NP_001259904.1	Gene:	CG4259 / 33385	FlyBaseID:	FBgn0031389	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	XP_031749235.1	Gene:	prss27 / 496619	XenbaseID:	XB-GENE-5744470	Length:	724	Species:	Xenopus tropicalis

Alignment Length:	257	Identity:	70/257 - (27%)
Similarity:	115/257 - (44%)	Gaps:	36/257 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 GSNPRATF---PWVVSVLDQRDWLFRYIGVGSLINPNVVLTAAHILNGTTKYD-LVVRAGEWD-T 91
            |:|  |.|   ||.||::.|..    :|..|||::.|.|::|||....:.|.: :.|..|.:. .
Frog   423 GNN--AVFGEWPWQVSIVYQNS----HICGGSLVSSNWVVSAAHCFPRSYKIENMQVLLGCFALM 481

  Fly    92 STTADQQHVDLEVLNIVSHEQFNRFNAENNMALLILVSAFEMTANINLIPLYLQEAGIQKGS-CF 155
            :.|:|.  |.:.|..::::..:....:..::|::.:.|....::.|..|.:.|.......|. |:
Frog   482 NLTSDA--VIIRVKRVITYPLYTGEGSSGDIAMVEMESPVTYSSYILPICIPLTNEDFPSGKMCW 544

  Fly   156 FNGWGKVYLN---STDYPTVLKTVQVDLLSMGMC------SSRKLPIQQ------ICGKGLEGID 205
            ..|||.:..:   |..||  |:.|:|.|::...|      :|...|..|      ||....||..
Frog   545 VTGWGNIQSDVSLSPPYP--LQEVEVPLVNASSCDTMYHYNSDLNPATQLVHDDMICAGYPEGQK 607

  Fly   206 --CSGDGGAPLVCRILTYPYKYAQVGIVNWLSQKPVENTFIVFTNVAGLLPWIDYHLRLEAN 265
              |.||.|.||.|:...|   :...|||:|.......|...|:|.|:....||:.:|.|..:
Frog   608 DACQGDSGGPLACKSGNY---WFLTGIVSWGDGCAQPNRPGVYTKVSSFSSWINQYLVLNVS 666

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4259	NP_001259904.1	Tryp_SPc	39..259	CDD:238113	65/242 (27%)
CG4259	NP_001259904.1	Tryp_SPc	39..256	CDD:214473	63/239 (26%)
prss27	XP_031749235.1	Tryp_SPc	34..271	CDD:238113
prss27	XP_031749235.1	Tryp_SPc	420..659	CDD:238113	68/248 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910