DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4259 and masp2

DIOPT Version :9

Sequence 1:	NP_001259904.1	Gene:	CG4259 / 33385	FlyBaseID:	FBgn0031389	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	NP_001011037.1	Gene:	masp2 / 496446	XenbaseID:	XB-GENE-1007491	Length:	687	Species:	Xenopus tropicalis

Alignment Length:	262	Identity:	65/262 - (24%)
Similarity:	103/262 - (39%)	Gaps:	64/262 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 FPWVVSVLDQRDWLFRYIGVGSLINPNVVLTAAHILNGTTKYD----LVVRAGEWDTSTTADQQH 99
            |||.|.:....:     .|.|:|:..|.:|||||::   ..||    ::::.|   ..:|.|..:
Frog   455 FPWQVFINANNE-----RGGGALLLDNWILTAAHVV---YSYDDLSSILIKMG---FLSTQDSNY 508

  Fly   100 VDLEVLNIVSHEQFNRFNAENNMALLILVSAFEMTANINLIPLYLQEAGIQKGSC---------- 154
            :......:..||.:...:..|::||:.|.         |.:|  |.|..| .|.|
Frog   509 IRGWPEAVFIHEGYKPGHYNNDIALIKLK---------NKVP--LSEESI-LGICLPTKEKSYHI 561

  Fly   155 ----------FFNGWGKVYLNSTDYPTVLKTVQVDLLSMGMCSSR--KLPIQ------QICGKGL 201
                      ...|||......:.  ..|:.|:|:::....|.:.  ||..|      .||. |.
Frog   562 SHKDDDNHVGLVAGWGLTEAQRSS--RKLRFVEVNIVDHSTCKAEYAKLDAQYIVTENMICA-GF 623

  Fly   202 E-GI--DCSGDGGAPLVCRILTYPYKYAQVGIVNWLSQKPVENTFIVFTNVAGLLPWIDYHLRLE 263
            | |:  .|:||.|..|.. :.....|:...|||:|.....|...:.|:|.|...|.||:  ..::
Frog   624 EIGVKDSCAGDSGGALAF-MNAESKKWFVGGIVSWGVGCGVARQYGVYTKVTNYLDWIE--KTIQ 685

  Fly   264 AN 265
            ||
Frog   686 AN 687

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4259	NP_001259904.1	Tryp_SPc	39..259	CDD:238113	63/254 (25%)
CG4259	NP_001259904.1	Tryp_SPc	39..256	CDD:214473	61/251 (24%)
masp2	NP_001011037.1	CUB	30..139	CDD:238001
		FXa_inhibition	145..180	CDD:317114
		CUB	184..294	CDD:238001
		CCP	299..361	CDD:153056
		CCP	365..430	CDD:153056
		Tryp_SPc	443..680	CDD:214473	61/251 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910