DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4259 and CG11313

DIOPT Version :9

Sequence 1:	NP_001259904.1	Gene:	CG4259 / 33385	FlyBaseID:	FBgn0031389	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	NP_651821.3	Gene:	CG11313 / 43646	FlyBaseID:	FBgn0039798	Length:	370	Species:	Drosophila melanogaster

Alignment Length:	277	Identity:	80/277 - (28%)
Similarity:	119/277 - (42%)	Gaps:	58/277 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 YNQIRRETYGSNPRAT-FPWVVSVLDQR---DWLFRYIGVGSLINPNVVLTAAHILNGTTK---- 79
            ||||   |.|:....| |.|:| :|:.|   ....|....|||||...|:||||.::..|:
  Fly   113 YNQI---TKGNETVLTEFAWMV-LLEYRPHDGQQLRTYCAGSLINNRYVVTAAHCVSAATRARKG 173

  Fly    80 ---YDLVVRAGEWDTSTTAD-------QQHVDLEVLNIVSHEQFNRFNAENNMALLILVSAFEMT 134
               :.:.||.||.:||...|       .:.|.:.|..|..||.|......|::||:.|  |.|:.
  Fly   174 DVSFRVSVRLGEHNTSAVVDCLNGRCLPEPVQIAVEEIRIHESFGTRLFWNDIALIRL--AREVA 236

  Fly   135 ANINLIPLYL-QEAGI---QKGSCF-FNGWGKVYLNSTDYPTVLKTVQVDLLSMGMCSSRKLPI- 193
            .:.::.|:.| ...|:   |.|..| ..|||:. |.|...|..:| ::|..:..|:|..:...|
  Fly   237 YSPSIRPVCLPSTVGLQNWQSGQAFTVAGWGRT-LTSESSPVKMK-LRVTYVEPGLCRRKYASIV 299

  Fly   194 ----QQICGKG-LEGIDCSGDGGAPLVCRILTYPYKYAQVGIVN---------WLSQKPVENTFI 244
                ..:|.:| ..|..|.||.|.||:.   .:...:...|||:         |.:
  Fly   300 VLGDSHLCAEGRSRGDSCDGDSGGPLMA---FHEGVWVLGGIVSFGLNCGSRFWPA--------- 352

  Fly   245 VFTNVAGLLPWIDYHLR 261
            |:|||.....||..::|
  Fly   353 VYTNVLSYETWITQNIR 369

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4259	NP_001259904.1	Tryp_SPc	39..259	CDD:238113	72/256 (28%)
CG4259	NP_001259904.1	Tryp_SPc	39..256	CDD:214473	70/253 (28%)
CG11313	NP_651821.3	CLIP	24..78	CDD:288855
		Tryp_SPc	116..367	CDD:238113	76/270 (28%)
		Tryp_SPc	116..364	CDD:214473	74/267 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457331
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840