DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4259 and proca

DIOPT Version :9

Sequence 1:	NP_001259904.1	Gene:	CG4259 / 33385	FlyBaseID:	FBgn0031389	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	NP_956650.1	Gene:	proca / 393327	ZFINID:	ZDB-GENE-060824-5	Length:	434	Species:	Danio rerio

Alignment Length:	259	Identity:	73/259 - (28%)
Similarity:	112/259 - (43%)	Gaps:	34/259 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 QIR--RETYGSNPRATF-PWV----VSVLDQRDW-------LFRYIGVGSLINPNVVLTAAHILN 75
            |||  :..|.:.|:... |||    |....:..|       |.|:...|.||:.|.||||||.|.
Zfish   175 QIRIPKSAYANKPKPVLQPWVMGGNVGKRGESPWQALILNHLGRFHCGGVLIDENWVLTAAHCLE 239

  Fly    76 GTTKYDLVVRAGEWDTSTTADQQHVDLEVLNIVSHEQFNRFNAENNMALLILVSAFEMTANINLI 140
            .::|:.  ||.|::. ....:...|.|.|...:||.|:|....:|::|||.|....:.:..|  :
Zfish   240 TSSKFS--VRLGDYQ-RFKFEGSEVTLPVKQHISHPQYNPITVDNDIALLRLDGPVKFSTYI--L 299

  Fly   141 PLYLQEAGIQKGSCFFN-------GWGKVYLNSTDYPTVLKTVQVDLLSMGMCS---SRKLPIQQ 195
            |..|....:.|.....|       ||||...::|.|.:.|..|::.::....||   ...|....
Zfish   300 PACLPSLELAKRMLHRNGTVTIITGWGKNNQSATSYNSTLHYVELPIVDNKECSRHMMNNLSDNM 364

  Fly   196 ICGKGLEGID--CSGDGGAPLVCRILTYPYKYAQVGIVNWLSQKPVENTFIVFTNVAGLLPWID 257
            :|...|..:.  |.||.|.|:   :..:...:..||:|:|.......:...::|.||..|.|||
Zfish   365 LCAGVLGQVKDACEGDSGGPM---MTLFHDTWFLVGLVSWGEGCGQRDKLGIYTKVASYLDWID 425

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4259	NP_001259904.1	Tryp_SPc	39..259	CDD:238113	68/243 (28%)
CG4259	NP_001259904.1	Tryp_SPc	39..256	CDD:214473	65/240 (27%)
proca	NP_956650.1	GLA	23..84	CDD:214503
		EGF_CA	85..119	CDD:238011
		FXa_inhibition	128..165	CDD:291342
		Tryp_SPc	195..427	CDD:238113	66/239 (28%)
		Tryp_SPc	197..424	CDD:214473	62/234 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910