DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4259 and CG30371

DIOPT Version :9

Sequence 1:	NP_001259904.1	Gene:	CG4259 / 33385	FlyBaseID:	FBgn0031389	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	NP_610370.1	Gene:	CG30371 / 35806	FlyBaseID:	FBgn0050371	Length:	399	Species:	Drosophila melanogaster

Alignment Length:	298	Identity:	63/298 - (21%)
Similarity:	118/298 - (39%)	Gaps:	70/298 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LYFAFLTT---------LIISLVNSQYFNYNQIRRETYGSNPRAT-FPWVVSVLDQRDWLFRYIG 57
            |.||:::|         .:.::..:....::...|...|....|. ||.:.::.|.......:.|
  Fly   115 LVFAYISTGTKGGSFKCTLTTVKQNCNCGWSATTRIANGQQAAANEFPSMAALKDVTKNQASFCG 179

  Fly    58 VGSLINPNVVLTAAHILNGTTK-YDLVVRAGEWDT-STTADQQHVDLEVLNIVSHEQF-NRFNAE 119
             |:::....:|||||.:...:: .::|...|..|. :.::.:.:....:..::.|||: :..:..
  Fly   180 -GTIVAHRYILTAAHCIYQVSRATNIVAIVGTNDLGNPSSSRYYQQYNIQQMIPHEQYVSDPDVN 243

  Fly   120 NNMALLILVSAFEMTANINLIPLYLQEAG------------IQKGSCFFNG-----WGKVYLN-- 165
            |::|:||..|..:.:..:.  |:.|...|            |..|:.||.|     ..|:.||
  Fly   244 NDIAVLITASNIQWSRGVG--PICLPPVGTSTPFTYDLVDVIGYGTVFFAGPTSTSLQKINLNVV 306

  Fly   166 -----STDYPTVLKTVQVDLLSMGMCSSRKLPIQQICGKGLEGIDCSGDGGAPLVCRILTYPYKY 225
                 .|:|..|     ..:.:..||:      ....|.|.:  .|..|.|.|::.|      |.
  Fly   307 TNQDCQTEYNNV-----ATIYTGQMCT------YDYSGTGRD--SCQFDSGGPVILR------KS 352

  Fly   226 AQ--VGIVNW-----LSQKPVENTFIVFTNVAGLLPWI 256
            .|  |||:::     .||.|:.    |.|.:...:.||
  Fly   353 RQFLVGIISYGKSCAESQYPMG----VNTRITSYISWI 386

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4259	NP_001259904.1	Tryp_SPc	39..259	CDD:238113	56/252 (22%)
CG4259	NP_001259904.1	Tryp_SPc	39..256	CDD:214473	54/250 (22%)
CG30371	NP_610370.1	CUB	24..>67	CDD:294042
		Tryp_SPc	149..386	CDD:214473	57/262 (22%)
		Tryp_SPc	150..389	CDD:238113	58/263 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24258
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100