DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4259 and prss60.3

DIOPT Version :9

Sequence 1:	NP_001259904.1	Gene:	CG4259 / 33385	FlyBaseID:	FBgn0031389	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	XP_002662541.2	Gene:	prss60.3 / 335152	ZFINID:	ZDB-GENE-030131-7092	Length:	330	Species:	Danio rerio

Alignment Length:	272	Identity:	78/272 - (28%)
Similarity:	117/272 - (43%)	Gaps:	48/272 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LTTLIISLVNSQYFNYNQIRRETYGSNPRATFPWVVSVLDQRDWLFRYIGVGSLINPNVVLTAAH 72
            |.|.|:..||               ::| .::||.|| |....:...:.| ||||:...||||||
Zfish    32 LNTRIVGGVN---------------ASP-GSWPWQVS-LHSPKYGGHFCG-GSLISSEWVLTAAH 78

  Fly    73 ILNGTTKYDLVVRAGE--------WDTSTTADQQHVDLEVLNIVSHEQFNRFNAENNMALLILVS 129
            .|:|.::..|||..|.        ::||....:..|         |..:|....:|::|||.|.|
Zfish    79 CLSGVSETTLVVYLGRRTQQGINIYETSRNVAKSFV---------HSSYNSNTNDNDIALLRLSS 134

  Fly   130 AFEMTANINLIPLYLQEAGIQKG-SCFFNGWGKVYLN-STDYPTVLKTVQVDLLSMGMCS----S 188
            |...|..|..:.|..|.:....| |.:..|||.:... :...|.:|:...:.:::...|:    |
Zfish   135 AVTFTNYIRPVCLAAQNSVYSAGTSSWITGWGDIQAGVNLPAPGILQETMIPVVANDRCNALLGS 199

  Fly   189 RKLPIQQICGKGLE--GID-CSGDGGAPLVCRILTYPYKYAQVGIVNWLSQKPVENTFIVFTNVA 250
            ..:....||. ||.  |.| |.||.|.|:|.|:.|.   :.|.||.:|.......|:..|:|.|:
Zfish   200 GTVTNNMICA-GLTQGGKDTCQGDSGGPMVTRLCTV---WVQAGITSWGYGCADPNSPGVYTRVS 260

  Fly   251 GLLPWIDYHLRL 262
            ....||...:.|
Zfish   261 QYQSWISSKISL 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4259	NP_001259904.1	Tryp_SPc	39..259	CDD:238113	71/236 (30%)
CG4259	NP_001259904.1	Tryp_SPc	39..256	CDD:214473	69/233 (30%)
prss60.3	XP_002662541.2	Tryp_SPc	36..269	CDD:238113	75/263 (29%)
prss60.3	XP_002662541.2	Somatomedin_B	294..328	CDD:321959
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587582
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930