DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4259 and CLIPB3

DIOPT Version :9

Sequence 1:	NP_001259904.1	Gene:	CG4259 / 33385	FlyBaseID:	FBgn0031389	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	XP_307750.3	Gene:	CLIPB3 / 3290783	VectorBaseID:	AGAP003249	Length:	365	Species:	Anopheles gambiae

Alignment Length:	255	Identity:	75/255 - (29%)
Similarity:	118/255 - (46%)	Gaps:	55/255 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 FPWVVSVLDQR-DWLFRYIGVGSLINPNVVLTAAHILNGTTKYDLV--VRAGEWDTSTTADQQH- 99
            |||...:..|: |..|.:...|||||...::||||.:....:...|  ||.||||.::..|.|:
Mosquito   124 FPWTALIEFQKPDGSFGFHCGGSLINDRYIVTAAHCIKSIPRGWKVHRVRLGEWDLTSANDCQNE 188

  Fly   100 ------VDLEVLNIVSHEQF---NRFNAENNMALLILVSAFEMTANINLIPLYL-------QEAG 148
                  :||::..||.|..:   ::.|| |::||:........:..:..|.|.|       ..||
Mosquito   189 FCSDAPIDLDIEQIVVHTGYDTKDQSNA-NDIALIRFTRPVNYSQTVRPICLPLSSSLRNRNHAG 252

  Fly   149 IQKGSCFFNGWGKVYLNSTDYPTVLKTVQVDLLSMGMCSSRKLPIQQ----------ICGKGLEG 203
            :   ..:..||||.. ::|.....|| |::::.|:..|:    |:.|          :|..|:.|
Mosquito   253 M---PAYAAGWGKTE-SATASEKKLK-VEMNIKSLQECA----PVYQRGGILLKKTHMCAGGVRG 308

  Fly   204 ID-CSGDGGAPLVCRILTYPYKYAQVGIVNWLSQK------PVENTFIVFTNVAGLLPWI 256
            .| ||||.|.||:.::....|   .:|:|::..||      |.     |:||||..:.||
Mosquito   309 KDTCSGDSGGPLMRQMSGSWY---LIGVVSFGPQKCGAPGVPG-----VYTNVAEYVDWI 360

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4259	NP_001259904.1	Tryp_SPc	39..259	CDD:238113	75/255 (29%)
CG4259	NP_001259904.1	Tryp_SPc	39..256	CDD:214473	73/253 (29%)
CLIPB3	XP_307750.3	CLIP	37..89	CDD:288855
		Tryp_SPc	112..360	CDD:214473	73/253 (29%)
		Tryp_SPc	113..363	CDD:238113	75/255 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910