DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4259 and Ser7

DIOPT Version :9

Sequence 1:	NP_001259904.1	Gene:	CG4259 / 33385	FlyBaseID:	FBgn0031389	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster

Alignment Length:	264	Identity:	65/264 - (24%)
Similarity:	101/264 - (38%)	Gaps:	54/264 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 FPWVV-----SVLDQRDWLFRYIGVGSLINPNVVLTAAHILNGTTKYDLVVRAGEWDTSTTADQQ 98
            |||..     :|...:|    |....|.|....:|||||.::...:.......|||:..|..|.:
  Fly   143 FPWTTLLEYETVSGGKD----YACGASFIAQRWLLTAAHCIHTMGRNLTAAILGEWNRDTDPDCE 203

  Fly    99 ------------HVDLEVLNIVSHEQFNRFNAENNMALLILVSAFEMTANINLIPLYL------- 144
                        |:.:.:..|:.|.|::..|..|::|||.|..........||.|:.|
  Fly   204 NDLNGVRECAPPHIRVTIDRILPHAQYSELNYRNDIALLRLSRPVNWLQMQNLEPVCLPPQRGRY 268

  Fly   145 --QEAGIQKGSCFFNGWGKVYLNSTDYPTVLKTVQVDLLSMGMCSSR-------KLPIQQICGKG 200
              |.||   .:...:||||.  .|:....:.:...:.:.....|...       .|...|:|..|
  Fly   269 ANQLAG---SAADVSGWGKT--ESSGSSKIKQKAMLHIQPQDQCQEAFYKDTKITLADSQMCAGG 328

  Fly   201 LEGID-CSGDGGAPLVCRILT-----YPYKYAQVGIVNWLSQKPVENTFI--VFTNVAGLLPWID 257
            ..|:| ||||.|.||.....|     |.|   ..|:|: :.:|.......  ::|.|:..:.||:
  Fly   329 EIGVDSCSGDSGGPLTVEANTASGNRYVY---LAGVVS-IGRKHCGTALFSGIYTRVSSYMDWIE 389

  Fly   258 YHLR 261
            ..:|
  Fly   390 STIR 393

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4259	NP_001259904.1	Tryp_SPc	39..259	CDD:238113	64/260 (25%)
CG4259	NP_001259904.1	Tryp_SPc	39..256	CDD:214473	62/257 (24%)
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	62/257 (24%)
		Tryp_SPc	133..391	CDD:238113	64/260 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24258
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010