DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4259 and Tmprss3

DIOPT Version :9

Sequence 1:	NP_001259904.1	Gene:	CG4259 / 33385	FlyBaseID:	FBgn0031389	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	XP_038954650.1	Gene:	Tmprss3 / 309665	RGDID:	1310135	Length:	454	Species:	Rattus norvegicus

Alignment Length:	265	Identity:	75/265 - (28%)
Similarity:	107/265 - (40%)	Gaps:	52/265 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 GSNPR---------ATFPWVVSVLDQRDWLFRYIGVGSLINPNVVLTAAHILNGTTKYDL----- 82
            |.:||         ..:||.||:..|.   :...| ||:|.|..::||||.:     |||
  Rat   212 GYSPRIVGGNVSSLTQWPWQVSLQFQG---YHLCG-GSVITPLWIVTAAHCV-----YDLYHPKS 267

  Fly    83 -VVRAGEWDTSTTADQQHVDLEVLNIVSHEQFNRFNAENNMALLILVSAFEMTANINLIPLYLQE 146
             .|:.|......:....|:   |..|:.|.::......|::||:.|.........|..|.|...|
  Rat   268 WTVQVGLVSLMDSPVPSHL---VEKIIYHSKYKPKRLGNDIALMKLSEPLTFDETIQPICLPNSE 329

  Fly   147 AGIQKGS-CFFNGWGKVYLNSTDYPTVLKTVQVDLLSMGMCSSRK-----LPIQQICGKGLE-GI 204
            .....|. |:.:|||.....:.|...||....|.|:|..:|:.|.     :....:|...|: |:
  Rat   330 ENFPDGKLCWTSGWGATEDGAGDASPVLNHAAVPLISNKICNHRDVYGGIISPSMLCAGYLKGGV 394

  Fly   205 D-CSGDGGAPLVC--RILTYPYKYAQVGI----VNWLSQKPVENTFIVFTNVAGLLPWIDYHLRL 262
            | |.||.|.||||  |.|.........||    ||    ||.     |:|.:...|.||  |.:|
  Rat   395 DSCQGDSGGPLVCQERRLWKLVGATSFGIGCAEVN----KPG-----VYTRITSFLDWI--HEQL 448

  Fly   263 EANFR 267
            |.:.:
  Rat   449 ERDLK 453

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4259	NP_001259904.1	Tryp_SPc	39..259	CDD:238113	69/239 (29%)
CG4259	NP_001259904.1	Tryp_SPc	39..256	CDD:214473	67/236 (28%)
Tmprss3	XP_038954650.1	LDLa	74..107	CDD:238060
		SRCR_2	112..211	CDD:406055
		Tryp_SPc	216..444	CDD:214473	68/248 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910