DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4259 and Sp212

DIOPT Version :9

Sequence 1:	NP_001259904.1	Gene:	CG4259 / 33385	FlyBaseID:	FBgn0031389	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	NP_996209.2	Gene:	Sp212 / 2768666	FlyBaseID:	FBgn0053329	Length:	516	Species:	Drosophila melanogaster

Alignment Length:	239	Identity:	56/239 - (23%)
Similarity:	112/239 - (46%)	Gaps:	18/239 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 PRATFPWVVSVLDQRDWLFRYIGVGSLINPNVVLTAAHILNGTTKYDLVVRAGEWDTSTTADQQH 99
            ||..:||:.:|..:......:...||||:.::|::|||.::..|:..:||..|.:|.....:...
  Fly   284 PRGQYPWLSAVYHKEVRALAFKCRGSLISSSIVISAAHCVHRMTEDRVVVGLGRYDLDDYGEDGA 348

  Fly   100 VDLEVLNIVSHEQFN-RFNAENNMALLILVSAFEMTANINLIPLYLQEAGIQKGSC-FFNGWGKV 162
            ....|:.::.|..:| |..::.::||:.:.........|..|.::..||.....:. |..|||:.
  Fly   349 EMRNVMRLLWHPDYNTRSYSDADIALITIERPVTFNDIIAPICMWTVEASRTVSTTGFIAGWGRD 413

  Fly   163 YLNS-TDYPTVLKTVQVDLLSMGMCSS----RKLPIQQICGKGLEGI-DCSGDGGAPLVCRILTY 221
            ..:| |.||.|   |:.::.|..:|:|    ..:..:.:|....:|. .|.||.|..|:.:   .
  Fly   414 EDSSRTQYPRV---VEAEIASPTVCASTWRGTMVTERSLCAGNRDGSGPCVGDSGGGLMVK---Q 472

  Fly   222 PYKYAQVGIVNWLSQKPVE----NTFIVFTNVAGLLPWIDYHLR 261
            ..::...|||:...:.|..    |.::::.:::..:.||..::|
  Fly   473 GDRWLLRGIVSAGERGPAGTCQLNQYVLYCDLSKHINWISENIR 516

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4259	NP_001259904.1	Tryp_SPc	39..259	CDD:238113	53/231 (23%)
CG4259	NP_001259904.1	Tryp_SPc	39..256	CDD:214473	51/228 (22%)
Sp212	NP_996209.2	GD_N	23..122	CDD:292649
		Tryp_SPc	277..514	CDD:238113	55/235 (23%)
		Tryp_SPc	277..511	CDD:214473	53/232 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24258
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100