DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4259 and Plau

DIOPT Version :9

Sequence 1:	NP_001259904.1	Gene:	CG4259 / 33385	FlyBaseID:	FBgn0031389	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	NP_037217.3	Gene:	Plau / 25619	RGDID:	3343	Length:	432	Species:	Rattus norvegicus

Alignment Length:	217	Identity:	63/217 - (29%)
Similarity:	94/217 - (43%)	Gaps:	19/217 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 GSLINPNVVLTAAH-ILNGTTKYDLVVRAGEWDTSTTADQQHVDLEVLNIVSHEQFN--RFNAEN 120
            ||||:|..|.:|.| .:|...|.:.||..|: ....:.:...:..||..::.||.|:  .....|
  Rat   212 GSLISPCWVASATHCFVNQPKKEEYVVYLGQ-SKRNSYNPGEMKFEVEQLILHEDFSDETLAFHN 275

  Fly   121 NMALLILVSAFEMTA----NINLIPLYLQEAGIQKGS-CFFNGWGKVYLNSTDYPTVLKTVQVDL 180
            ::|||.:.::....|    .|..|.|..:......|| |...|:|:.......||..||...|.:
  Rat   276 DIALLKIRTSTGQCAQPSRTIQTICLPPRFGDAPFGSDCEITGFGQESATDYFYPKDLKMSVVKI 340

  Fly   181 LSMGMCS-----SRKLPIQQICGKGLE--GIDCSGDGGAPLVCRILTYPYKYAQVGIVNWLSQKP 238
            :|...|.     ..::..:.:|....|  ...||||.|.||:|.|...|   ...|||:|.|...
  Rat   341 ISHEQCKQPHYYGSEINYKMLCAADPEWKTDSCSGDSGGPLICNIDGRP---TLSGIVSWGSGCA 402

  Fly   239 VENTFIVFTNVAGLLPWIDYHL 260
            .:|...|:|.|:..|.||..|:
  Rat   403 EKNKPGVYTRVSYFLNWIQSHI 424

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4259	NP_001259904.1	Tryp_SPc	39..259	CDD:238113	62/214 (29%)
CG4259	NP_001259904.1	Tryp_SPc	39..256	CDD:214473	60/211 (28%)
Plau	NP_037217.3	Binds urokinase plasminogen activator surface receptor	34..57
		KR	67..152	CDD:238056
		Connecting peptide	152..178
		Tryp_SPc	178..420	CDD:214473	60/211 (28%)
		Tryp_SPc	179..423	CDD:238113	62/214 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910