DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4259 and Proc

DIOPT Version :9

Sequence 1:	NP_001259904.1	Gene:	CG4259 / 33385	FlyBaseID:	FBgn0031389	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	XP_008770240.3	Gene:	Proc / 25268	RGDID:	3411	Length:	500	Species:	Rattus norvegicus

Alignment Length:	237	Identity:	68/237 - (28%)
Similarity:	111/237 - (46%)	Gaps:	28/237 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 PWVVSVLDQRDWLFRYIGVGSLINPNVVLTAAHILNGTTKYDLVVRAGEWDTSTTADQQHVDLEV 104
            ||...:||.:..|  ..| |.||:.:.||||||.|..:.|  |.||.||:|. ...|...:||::
  Rat   264 PWQAILLDSKKKL--ACG-GVLIHTSWVLTAAHCLESSKK--LTVRLGEYDL-RRRDPWELDLDI 322

  Fly   105 LNIVSHEQFNRFNAENNMALLILVSAFEMTANINLIPLYLQEAGI-----QKG-SCFFNGWG--- 160
            ..::.|..:.|.|::|::|||.|  :...|.:..::|:.|..:|:     |.| .....|||
  Rat   323 KEVLVHPNYTRSNSDNDIALLRL--SQPATLSKTIVPICLPNSGLAQELSQAGQETVVTGWGYQS 385

  Fly   161 -KVYLNSTDYPTVLKTVQVDLLSMGMC---SSRKLPIQQICGKGLEGID---CSGDGGAPLVCRI 218
             ||.....:...:|..:::.|.:...|   .:..:....:|. |:.|..   |.||.|.|:|
  Rat   386 DKVKDGRRNRTFILTFIRIPLAARNDCMQVMNNVVSENMLCA-GIIGDTRDACDGDSGGPMV--- 446

  Fly   219 LTYPYKYAQVGIVNWLSQKPVENTFIVFTNVAGLLPWIDYHL 260
            :.:...:..||:|:|.......|.:.|:|.|...|.||..::
  Rat   447 VFFRGTWFLVGLVSWGEGCGHLNNYGVYTKVGSYLKWIHSYI 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4259	NP_001259904.1	Tryp_SPc	39..259	CDD:238113	68/234 (29%)
CG4259	NP_001259904.1	Tryp_SPc	39..256	CDD:214473	66/231 (29%)
Proc	XP_008770240.3	GLA	65..125	CDD:214503
		EGF_CA	126..170	CDD:238011
		FXa_inhibition	178..213	CDD:405372
		Tryp_SPc	252..486	CDD:238113	68/233 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910