DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4259 and CG30375

DIOPT Version :9

Sequence 1:	NP_001259904.1	Gene:	CG4259 / 33385	FlyBaseID:	FBgn0031389	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	NP_724665.1	Gene:	CG30375 / 246575	FlyBaseID:	FBgn0050375	Length:	398	Species:	Drosophila melanogaster

Alignment Length:	239	Identity:	59/239 - (24%)
Similarity:	103/239 - (43%)	Gaps:	57/239 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 FPWVVSVLDQRDWLFRYIGVGSLINPNVVLTAAHILNGTTKYDLVVR----AGEWDTSTTADQQH 99
            ||.:|.:.|....|..:.| ||:::...::||||.   |.:..:..|    .||.|.||.|:..:
  Fly   163 FPSMVGLRDLSSNLPIFCG-GSIVSERYIMTAAHC---TARQPVASRLLALVGEHDLSTGAESIY 223

  Fly   100 -VDLEVLNIVSHEQFNRFNAE--NNMALLILVSAFEMTANINLIPLYLQEAGIQKGSCFFN---- 157
             ....:.||::|..:....:.  |::|||...:..|.:..:..|.|.:::|   :.|  ||
  Fly   224 AAQYRIQNIINHPGYMETASGNINDIALLQTATPIEWSRGVAPICLPIRQA---ENS--FNYQNV 283

  Fly   158 ---GWGKVYLNSTDYPTVLKTVQVDLLSM--GMCSSR---KLPIQQIC-----GKGLEGIDCSGD 209
               |||.:...::...|:.|..   ||:|  .:|.||   .:....:|     |:|.:  .|..|
  Fly   284 DIMGWGTLGFAASKSNTLQKAT---LLTMDNAVCRSRFNSSITPSHLCTYDAGGRGQD--SCQYD 343

  Fly   210 GGAPLVCR---------ILTYPYKYAQ---VGI-------VNWL 234
            .|.|::.|         :::|.....|   :|:       :|||
  Fly   344 SGGPVILRQRERMFQLGVISYGRACGQPFGIGVNTRVTSHLNWL 387

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4259	NP_001259904.1	Tryp_SPc	39..259	CDD:238113	59/239 (25%)
CG4259	NP_001259904.1	Tryp_SPc	39..256	CDD:214473	59/239 (25%)
CG30375	NP_724665.1	CUB	38..>100	CDD:294042
		Tryp_SPc	151..386	CDD:214473	56/236 (24%)
		Tryp_SPc	152..387	CDD:238113	57/237 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24258
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100