DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4259 and Tmprss13

DIOPT Version :9

Sequence 1:	NP_001259904.1	Gene:	CG4259 / 33385	FlyBaseID:	FBgn0031389	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	XP_006510195.1	Gene:	Tmprss13 / 214531	MGIID:	2682935	Length:	561	Species:	Mus musculus

Alignment Length:	253	Identity:	67/253 - (26%)
Similarity:	110/253 - (43%)	Gaps:	48/253 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 FPWVVSVLDQRDWLFRYIGV-----GSLINPNVVLTAAH--------ILNGTTKYDLVVRAGEWD 90
            :||.||:         :.|.     |:||:...||||||        :|.|...|     ||
Mouse   331 WPWQVSL---------HFGTTHICGGTLIDAQWVLTAAHCFFVTREKLLEGWKVY-----AG--- 378

  Fly    91 TSTTADQQHVDLEVLNIVSHEQFNRFNAENNMALLILVSAFEMTANIN--LIPLYLQEAGIQKGS 153
             ::...|......:..|:.:..:.....:.::||:.|.....::|:|:  .:|::.|..|:.: :
Mouse   379 -TSNLHQLPEAASISQIIINGNYTDEQDDYDIALIRLSKPLTLSAHIHPACLPMHGQTFGLNE-T 441

  Fly   154 CFFNGWGKVYLNSTDYPT--VLKTVQVDLLSMGMCS-----SRKLPIQQICGKGLEG--IDCSGD 209
            |:..|:||.  ..||..|  .|:.|||:|:....|:     ...|..:.:|...|.|  ..|.||
Mouse   442 CWITGFGKT--KETDEKTSPFLREVQVNLIDFKKCNDYLVYDSYLTPRMMCAGDLRGGRDSCQGD 504

  Fly   210 GGAPLVCRILTYPYKYAQVGIVNWLSQKPVENTFIVFTNVAGLLPWIDYHLRLEANFR 267
            .|.||||.   ...::...|:.:|.:....:|...|:|.|..:||||...:..|..||
Mouse   505 SGGPLVCE---QNNRWYLAGVTSWGTGCGQKNKPGVYTKVTEVLPWIYRKMESEVRFR 559

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4259	NP_001259904.1	Tryp_SPc	39..259	CDD:238113	64/243 (26%)
CG4259	NP_001259904.1	Tryp_SPc	39..256	CDD:214473	62/240 (26%)
Tmprss13	XP_006510195.1	PHA03378	<6..>122	CDD:223065
		LDLa	<204..220	CDD:238060
		SRCR_2	225..314	CDD:373897
		Tryp_SPc	319..548	CDD:214473	62/240 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910