DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG4259 and PRSS55

DIOPT Version :9

Sequence 1:NP_001259904.1 Gene:CG4259 / 33385 FlyBaseID:FBgn0031389 Length:270 Species:Drosophila melanogaster
Sequence 2:NP_940866.2 Gene:PRSS55 / 203074 HGNCID:30824 Length:352 Species:Homo sapiens


Alignment Length:253 Identity:81/253 - (32%)
Similarity:122/253 - (48%) Gaps:49/253 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly    39 FPWVVSVLDQRDWLFRYIGVGSLINPNVVLTAAHILNGTTKY--DLVVRAGEWD-TSTTADQQHV 100
            |||.||:..:.:   .:.| ||::|...:|||||.|.....:  :|.|..|..| ||.:.:.:  
Human    79 FPWQVSIQARSE---PFCG-GSILNKWWILTAAHCLYSEELFPEELSVVLGTNDLTSPSMEIK-- 137

  Fly   101 DLEVLNIVSHEQFNRFNAENNMALLILVSAFEMTANINL-IPLYLQEAGIQKG-----SCFFNGW 159
              ||.:|:.|:.|.|.|.:|::|||:|.|..::.   :| :|:.|.   .|.|     .|:..||
Human   138 --EVASIILHKDFKRANMDNDIALLLLASPIKLD---DLKVPICLP---TQPGPATWRECWVAGW 194

  Fly   160 GKVYLNSTDYPTVLKTVQVDLLSMGM-------CSSR--KLPIQQIC-GKGLEGID-CSGDGGAP 213
            |:.  |:.|    ..:|:.||:...|       ||..  ||....:| |...|..| |.||.|.|
Human   195 GQT--NAAD----KNSVKTDLMKAPMVIMDWEECSKMFPKLTKNMLCAGYKNESYDACKGDSGGP 253

  Fly   214 LVCRILTYP---YKYAQVGIVNWLSQKPVENTFIVFTNVAGLLPWIDYHLRLEANFRP 268
            |||.    |   .|:.||||::|......:||..::|::.....||:...:||.  ||
Human   254 LVCT----PEPGEKWYQVGIISWGKSCGEKNTPGIYTSLVNYNLWIEKVTQLEG--RP 305

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4259NP_001259904.1 Tryp_SPc 39..259 CDD:238113 77/242 (32%)
Tryp_SPc 39..256 CDD:214473 75/239 (31%)
PRSS55NP_940866.2 Tryp_SPc 67..295 CDD:214473 75/239 (31%)
Tryp_SPc 68..298 CDD:238113 77/242 (32%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 308..330
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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