DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4259 and CLIPB11

DIOPT Version :9

Sequence 1:	NP_001259904.1	Gene:	CG4259 / 33385	FlyBaseID:	FBgn0031389	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	XP_319991.3	Gene:	CLIPB11 / 1280172	VectorBaseID:	AGAP009214	Length:	359	Species:	Anopheles gambiae

Alignment Length:	258	Identity:	77/258 - (29%)
Similarity:	117/258 - (45%)	Gaps:	38/258 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 RETYGSNPRA-TFPWVVSVLDQRDWLFRYIGVGSLINPNVVLTAAHIL--NGTTKYDLVVRAGEW 89
            |..:|.:.|. .:|| :::|.||  ...::..|:|||...||||||.:  |..|    .||.||:
Mosquito   113 RIAFGQDARLFQYPW-MALLKQR--AGNFVCGGTLINERYVLTAAHCIKNNDIT----TVRLGEF 170

  Fly    90 DTSTTAD-----QQHV----DLEVLNIVSHEQFNRFNAENNMALLILVSAFEMTANINLIPLYLQ 145
            |.||..|     :|..    ||.|...:.||.::....||::.|:.|  |.|...|.|::|:.|.
Mosquito   171 DLSTPIDCDKRGEQCAPPPQDLFVEQTIVHEAYSARRKENDIGLVRL--AKEAEYNDNVLPICLP 233

  Fly   146 EAGIQK---GSCFFNGWGKVYLNSTDYPTVLKTVQVDLLSMGMCSSRKLPI--------QQICGK 199
            .....:   .:.|..|||..  .|......|:..::.|||...|..:.|.:        .|:|..
Mosquito   234 VTPAMRTTQTTYFVAGWGAT--ESAPSSNRLQFTKLSLLSNDQCVQKLLRVDSFAKVNNDQMCAI 296

  Fly   200 GLEGID-CSGDGGAPLVCRILTYPYKYAQVGIVNW-LSQKPVENTFIVFTNVAGLLPWIDYHL 260
            |....| |:||.|.||  :.::...:|.|.|:|:: |.....::...|:|.|.....||..||
Mosquito   297 GANLTDNCTGDSGGPL--KTISINARYVQYGVVSYGLRTCGKQSAPGVYTRVENYADWILEHL 357

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4259	NP_001259904.1	Tryp_SPc	39..259	CDD:238113	72/243 (30%)
CG4259	NP_001259904.1	Tryp_SPc	39..256	CDD:214473	70/240 (29%)
CLIPB11	XP_319991.3	Tryp_SPc	113..353	CDD:214473	73/252 (29%)
CLIPB11	XP_319991.3	Tryp_SPc	117..356	CDD:238113	74/251 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910