DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4259 and CLIPB13

DIOPT Version :9

Sequence 1:	NP_001259904.1	Gene:	CG4259 / 33385	FlyBaseID:	FBgn0031389	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	XP_314336.2	Gene:	CLIPB13 / 1275070	VectorBaseID:	AGAP004855	Length:	410	Species:	Anopheles gambiae

Alignment Length:	283	Identity:	73/283 - (25%)
Similarity:	116/283 - (40%)	Gaps:	60/283 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 IRRETYGSNPRA-TFPWVVSVLDQRDWLFRY--IGV------GSLINPNVVLTAAHILNGTTKYD 81
            :.|..:|:..|. .:||:|        |.||  .||      |||||...||||||.:..::...
Mosquito   148 VNRIAHGNTTRVFEYPWMV--------LLRYESNGVLSDRCGGSLINNRYVLTAAHCVRTSSSIR 204

  Fly    82 LV-VRAGEWDTSTTAD------------QQHVDLEVLNIVSHEQFNR-FNAENNMALLILVSAFE 132
            || ||.||.|.....|            ...||:::.:::.|:.:|| ....:::|||.:....|
Mosquito   205 LVKVRLGEHDKRQQIDCHVYSDGEKDCADPAVDVDIESMIVHKDYNRPIKFRHDIALLRMAQEVE 269

  Fly   133 MTANINLIPLYLQEAGIQK--GSCFFNGWG------------KVYLNSTDYPTVLKTVQVDLLSM 183
            .:.::..|.|.:.|...:|  ......|||            :..:|....|...:.:..:.|.:
Mosquito   270 FSDSVKPICLPVNEDVRRKVLPKYIITGWGTTEQQSLSDLLLQAIVNHVPVPECQQKMNENFLYV 334

  Fly   184 GMCSSRKLPIQQICGKGLEGI--DCSGDGGAPLVCRILTYPYKYAQVGIVN-WLSQKPVENTFIV 245
            .:...     .|:|..| ||:  .|.||.|.||...:.....|:.|.|||: .:.....|:...:
Mosquito   335 TLADE-----WQMCAAG-EGLVDSCQGDSGGPLGFSVDVAGAKFVQFGIVSAGVRSCGKESVPGI 393

  Fly   246 FTNVAGLLPWIDYHLRLEANFRP 268
            :|.|...:.||      .||.:|
Mosquito   394 YTRVTSYMNWI------VANMKP 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4259	NP_001259904.1	Tryp_SPc	39..259	CDD:238113	67/258 (26%)
CG4259	NP_001259904.1	Tryp_SPc	39..256	CDD:214473	65/255 (25%)
CLIPB13	XP_314336.2	CLIP	28..81	CDD:288855
		Tryp_SPc	150..404	CDD:214473	68/267 (25%)
		Tryp_SPc	151..404	CDD:238113	67/266 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910