DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4259 and CLIPB2

DIOPT Version :9

Sequence 1:	NP_001259904.1	Gene:	CG4259 / 33385	FlyBaseID:	FBgn0031389	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	XP_312956.3	Gene:	CLIPB2 / 1273920	VectorBaseID:	AGAP003246	Length:	355	Species:	Anopheles gambiae

Alignment Length:	260	Identity:	77/260 - (29%)
Similarity:	118/260 - (45%)	Gaps:	55/260 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 FPWVVSVL-----DQRDWLFRYIGVGSLINPNVVLTAAHI---------LNGTTKYDLVVRAGEW 89
            |||...:.     :|.|:   :.| |:|||...:|||||.         |||       ||.|||
Mosquito   114 FPWTALIEYRKPGNQYDF---HCG-GALINARYILTAAHCVQSLPRGWQLNG-------VRLGEW 167

  Fly    90 DTSTTADQQH-------VDLEVLNIVSHEQFNRFNA--ENNMALLIL---VSAFEMTANINLIPL 142
            |.||..|...       :|||:.:.|:|..::..:.  .|::||:.|   |::.||...|.|...
Mosquito   168 DLSTANDCSDGICSAGPIDLEIESFVAHAGYDAADTAHTNDIALIRLRQDVASSEMIRPICLPLT 232

  Fly   143 YLQEAGIQKGS-CFFNGWGKVYLNSTDYPTVLKTVQVDLLSMGMCSSRK--------LPIQQICG 198
            ..|.:..:.|: .|..||||....|...    :.::|:|........|:        |...|:|.
Mosquito   233 EPQRSRNRVGTVSFAAGWGKTESASASE----RKLKVELTVQDPSRCRQIYRGINIALKASQMCA 293

  Fly   199 KGLEGID-CSGDGGAPLVCRILTYPYKYAQVGIVNW-LSQKPVENTFIVFTNVAGLLPWIDYHLR 261
            .||:|.| |:||.|.||:.:.....|   .:|:|:: ||:........|:|||...|.||:.:::
Mosquito   294 GGLQGKDTCTGDSGGPLMAKSAGAWY---LIGVVSFGLSKCGTAGYPGVYTNVVEYLDWIESNVQ 355

Fly 262 261
Mosquito 356 355

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4259	NP_001259904.1	Tryp_SPc	39..259	CDD:238113	77/256 (30%)
CG4259	NP_001259904.1	Tryp_SPc	39..256	CDD:214473	75/253 (30%)
CLIPB2	XP_312956.3	CLIP	26..78	CDD:288855
		Tryp_SPc	102..350	CDD:214473	75/253 (30%)
		Tryp_SPc	103..353	CDD:238113	77/256 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910