DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4259 and AgaP_AGAP010730

DIOPT Version :9

Sequence 1:	NP_001259904.1	Gene:	CG4259 / 33385	FlyBaseID:	FBgn0031389	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	XP_311444.4	Gene:	AgaP_AGAP010730 / 1272531	VectorBaseID:	AGAP010730	Length:	256	Species:	Anopheles gambiae

Alignment Length:	253	Identity:	81/253 - (32%)
Similarity:	119/253 - (47%)	Gaps:	44/253 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 ATFPWVVSVL-------DQRDWLFRYIGVGSLINPNVVLTAAHILNGTTKYDLVVRAGEWDTSTT 94
            |.:||||.:|       :..|    ::..|:||:..:|:|.||..:|.|  |||.|.||||.|||
Mosquito     6 AEYPWVVYILALKKQEANSGD----FVCGGTLIHSRLVVTTAHNTDGKT--DLVARFGEWDISTT 64

  Fly    95 AD---QQ----HVDLEVLNIVSHEQFNRFNAENNMALLILVSAFEMTANINLIPLYLQEAGIQKG 152
            .:   ||    |.|::|..::.|.|:.....:|::|||:|....:..|:|..|.|..........
Mosquito    65 KEPFPQQCLFPHQDIDVAEVIKHPQYVFNPIQNDIALLVLAENVQYAAHIRPICLPQPTDEFVGQ 129

  Fly   153 SCFFNGWGK---VYLNSTDYPTVLKTVQVDLLSMGMCSSRKL------PIQQ-----ICGKGLEG 203
            .|..|||||   ||.|      |:|.:.:.::....| :|.|      |...     :|..|...
Mosquito   130 RCVSNGWGKERGVYAN------VMKKLTLPVIGRANC-TRMLRYAGLGPFYTLREGFLCAGGEVA 187

  Fly   204 ID-CSGDGGAPLVCRILTYPYKYAQVGIVNWLSQKPVENTFIVFTNVAGLLPWIDYHL 260
            :| |.||||:||.|:  |....|...|||:|.......||..|:..|...:.|::.|:
Mosquito   188 VDMCKGDGGSPLACQ--TESGTYVLAGIVSWGIGCGGFNTPGVYVAVNRYVQWLNEHI 243

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4259	NP_001259904.1	Tryp_SPc	39..259	CDD:238113	79/248 (32%)
CG4259	NP_001259904.1	Tryp_SPc	39..256	CDD:214473	78/245 (32%)
AgaP_AGAP010730	XP_311444.4	Tryp_SPc	7..242	CDD:238113	79/249 (32%)
AgaP_AGAP010730	XP_311444.4	Tryp_SPc	7..238	CDD:214473	78/245 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	2	1.870