DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4259 and AgaP_AGAP000290

DIOPT Version :9

Sequence 1:	NP_001259904.1	Gene:	CG4259 / 33385	FlyBaseID:	FBgn0031389	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	XP_310831.5	Gene:	AgaP_AGAP000290 / 1271969	VectorBaseID:	AGAP000290	Length:	499	Species:	Anopheles gambiae

Alignment Length:	237	Identity:	70/237 - (29%)
Similarity:	104/237 - (43%)	Gaps:	25/237 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 FPWVVSVLDQ-RDWLFRYIGVGSLINPNVVLTAAHILNGTTKYD--LVVRAGEWDTSTTADQ-QH 99
            |||.|::... |:..:.|...|:|:|.:||:||||.::....:.  .||.||:||...|.:: .|
Mosquito   266 FPWTVAIHQLIRNGSYVYHCGGALLNQSVVVTAAHCVSNNRLHPNRFVVYAGDWDRRHTQERLPH 330

  Fly   100 VDLEVLNIVSHEQFNRFNAENNMALLILVSAFEMTANINLIPLYLQEAG----IQKGSCFFNGWG 160
            .:..|..::.|..:......|::|||.....|..|. .|:.|:.|....    |...:||..|||
Mosquito   331 QERTVSRVLVHPNYYSGALFNDLALLFFSEPFNDTV-ANVEPVCLSSPSGTDYIPPDNCFVTGWG 394

  Fly   161 KV----YLNSTDYPTVLKTV-----QVDLLSMGMCSSR-KLPIQQICGKGLEGID-CSGDGGAPL 214
            ..    ...|....:.|:.|     :..|.|:....|: ||....:|. ..:|.| |.|.||:|.
Mosquito   395 GSPKGNRAQSIQQYSKLQLVERHRCETQLQSLPTLGSKFKLHQSFVCA-ATDGTDVCQGSGGSPY 458

  Fly   215 VCRILTYPYKYAQVGIVNWLSQKPVENTFIVFTNVAGLLPWI 256
            .|.   ...:|..||||:| .....:....|.|||..|..||
Mosquito   459 ACE---RDGRYYLVGIVSW-GVGCGDGIPAVLTNVTELREWI 496

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4259	NP_001259904.1	Tryp_SPc	39..259	CDD:238113	70/237 (30%)
CG4259	NP_001259904.1	Tryp_SPc	39..256	CDD:214473	68/235 (29%)
AgaP_AGAP000290	XP_310831.5	Tryp_SPc	265..499	CDD:238113	70/237 (30%)
AgaP_AGAP000290	XP_310831.5	Tryp_SPc	265..496	CDD:214473	68/235 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BM7R
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.770