DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4259 and AgaP_AGAP007280

DIOPT Version :9

Sequence 1:	NP_001259904.1	Gene:	CG4259 / 33385	FlyBaseID:	FBgn0031389	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	XP_308537.4	Gene:	AgaP_AGAP007280 / 1269883	VectorBaseID:	AGAP007280	Length:	2275	Species:	Anopheles gambiae

Alignment Length:	244	Identity:	60/244 - (24%)
Similarity:	107/244 - (43%)	Gaps:	36/244 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 SNPRATFPWVVSVLDQRDWLFRYIGVGSLINPNVVLTAAHILNGTTKYDLVVRAGEWDTSTTADQ 97
            ::|.| :|::|.:.  ||.  :|...||:.|.:.:::|||..:...::...||:|.....:.|.|
Mosquito   948 ADPEA-YPFIVGIF--RDG--KYHCGGSIYNEHWIISAAHCCDNFDQHYFEVRSGMLRKRSFAPQ 1007

  Fly    98 QHVDLEVLNIVSHEQFNRFNAENNMALLILVSAFEMTANINLIPLYLQEA-----------GIQK 151
            ..: ..|.:::.|..::.....|::||:.:...|.....:.  |:.:.|.           |.:.
Mosquito  1008 VQI-TRVTHMIVHHAYSSSLMANDIALMRVEHPFHYNRWVR--PICMPERHRTTDDRDWIWGPKA 1069

  Fly   152 GS-CFFNGWGKVYLNSTDYPTVLKTVQVDLLSMGMCSSRK-LPIQQICGKGLEG--IDCSGDGGA 212
            |: |...|||.: ......|..|..|.|.:|  |.|..:. ....|||....:|  ..|.||.|.
Mosquito  1070 GTVCTAIGWGAL-RERGGAPDHLMQVSVPIL--GYCKHKSDRDSLQICAAEEDGGHDACQGDSGG 1131

  Fly   213 PLVCRILTYPYKYAQVGIVNW-----LSQKPVENTFIVFTNVAGLLPWI 256
            |.||:..:.|:::...|:|:.     .:.:|.     |:|.||..:.||
Mosquito  1132 PFVCQSKSNPFEWYLAGVVSHGEGCARAHEPG-----VYTRVALFIDWI 1175

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4259	NP_001259904.1	Tryp_SPc	39..259	CDD:238113	58/238 (24%)
CG4259	NP_001259904.1	Tryp_SPc	39..256	CDD:214473	56/236 (24%)
AgaP_AGAP007280	XP_308537.4	LDLa	698..733	CDD:238060
		Tryp_SPc	941..1175	CDD:214473	58/242 (24%)
		Tryp_SPc	942..1178	CDD:238113	60/244 (25%)
		LDLa	1196..1226	CDD:238060
		LDLa	1510..1541	CDD:238060
		LDLa	1574..1609	CDD:238060
		DUF1986	1774..1887	CDD:286432
		LDLa	1999..2025	CDD:238060
		LDLa	2038..2071	CDD:238060
		LDLa	2107..2142	CDD:238060
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910