DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4259 and AgaP_AGAP012946

DIOPT Version :9

Sequence 1:	NP_001259904.1	Gene:	CG4259 / 33385	FlyBaseID:	FBgn0031389	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	XP_003436544.1	Gene:	AgaP_AGAP012946 / 11175517	VectorBaseID:	AGAP012946	Length:	318	Species:	Anopheles gambiae

Alignment Length:	225	Identity:	62/225 - (27%)
Similarity:	103/225 - (45%)	Gaps:	23/225 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 DQRDWLFRYIGVGSLINPNVVLTAAHILNGTTKY--DLVVRAGEWDTSTTADQQHVDLEVLNIVS 109
            :|.|:.|| .| |:||:...:|||||..    .|  .::||.||:||....|.:: |.::.:|..
Mosquito    94 NQWDYDFR-CG-GTLISDQHILTAAHCF----AYGDPVIVRVGEYDTELETDDEY-DSDIASIRR 151

  Fly   110 HEQFNRFNAENNMALLILVSAFEMTANINLIPLYLQEAGIQKGSCFF-NGWGKVYLNSTDYPTVL 173
            |..::...:.:::||:.|.....::.:|.  |..|.|...:..:.:. .|:|......|...||:
Mosquito   152 HPNYSNLRSYDDIALVKLKHPIVLSKHIR--PACLWETEERNSTRYIATGFGYNETYGTTLSTVM 214

  Fly   174 KTVQVDLLSMGMCSSR-------KLPIQ--QIC-GKGLEGID-CSGDGGAPLVCRILTYPYKYAQ 227
            ..|.:|...:..|...       |..::  |:| |..:||.| |.||.|.||.....|....|..
Mosquito   215 MKVNLDEFPVSDCERNFKGDRRFKQGVRDGQLCVGSIVEGRDTCQGDSGGPLQVVTNTKSCSYGV 279

  Fly   228 VGIVNWLSQKPVENTFIVFTNVAGLLPWID 257
            |||.:......:.|...::|.|:..:.||:
Mosquito   280 VGITSVGGVCGIGNAKAIYTKVSHYIDWIE 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4259	NP_001259904.1	Tryp_SPc	39..259	CDD:238113	62/225 (28%)
CG4259	NP_001259904.1	Tryp_SPc	39..256	CDD:214473	60/222 (27%)
AgaP_AGAP012946	XP_003436544.1	Tryp_SPc	69..311	CDD:238113	62/225 (28%)
AgaP_AGAP012946	XP_003436544.1	Tryp_SPc	69..308	CDD:214473	60/222 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910