DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4259 and tmprss2.15

DIOPT Version :9

Sequence 1:	NP_001259904.1	Gene:	CG4259 / 33385	FlyBaseID:	FBgn0031389	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	XP_031752206.1	Gene:	tmprss2.15 / 101732233	XenbaseID:	XB-GENE-22065943	Length:	504	Species:	Xenopus tropicalis

Alignment Length:	253	Identity:	61/253 - (24%)
Similarity:	103/253 - (40%)	Gaps:	52/253 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 GSNPRAT--FPWVVSVLDQRDWLFRYIGV------GSLINPNVVLTAAHILNGTTKYD--LVVRA 86
            |..|.:.  :||.|.:|       :.:|.      ||:|.|:.::||||.:.|:|...  ..|.|
Frog   267 GGTPASVGDWPWQVELL-------KLVGTSIYLCGGSIITPHWIVTAAHCVYGSTSTPSAFKVFA 324

  Fly    87 GEWDTSTTADQQHVDLEVLNIVSHEQFNRFNAENNMALLILVSAFEMTANINLIPLYLQEAGI-- 149
            |   :.|..........|...:.|..::.:....::|||.|.:|...|.|:.  |:.|...|:
Frog   325 G---SLTIQSYYSAGYTVERALVHPSYSSYTQIYDVALLKLTAALVFTTNLR--PVCLPNVGMPW 384

  Fly   150 -QKGSCFFNGWGKVYLNSTDYPTVLKTV---QVDLLSMGMCSSR-----KLPIQQICGKGLEG-- 203
             :...|:.:|||    .:.:..::.|.:   .|.::|...|:..     .:....:|...|.|
Frog   385 AEGQPCWISGWG----TTAEGGSISKNLMAASVPIISSTTCNQAAVYGGAISSTMMCAGYLSGGT 445

  Fly   204 IDCSGDGGAPLVCRILTYPYKYAQVGIVNW-----LSQKPVENTFIVFTNVAGLLPWI 256
            ..|.||.|.|||.:..:.   :..||..:|     .:.||.     |:.||...:.||
Frog   446 DTCQGDSGGPLVTKTNSL---WWLVGDTSWGYGCARAYKPG-----VYGNVTVFIEWI 495

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4259	NP_001259904.1	Tryp_SPc	39..259	CDD:238113	59/244 (24%)
CG4259	NP_001259904.1	Tryp_SPc	39..256	CDD:214473	57/242 (24%)
tmprss2.15	XP_031752206.1	LDLa	93..121	CDD:238060
		SRCR_2	164..259	CDD:406055
		Tryp_SPc	265..498	CDD:238113	61/253 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910