DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4259 and f12

DIOPT Version :9

Sequence 1:	NP_001259904.1	Gene:	CG4259 / 33385	FlyBaseID:	FBgn0031389	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	XP_017947702.2	Gene:	f12 / 100493769	XenbaseID:	XB-GENE-1004811	Length:	597	Species:	Xenopus tropicalis

Alignment Length:	238	Identity:	65/238 - (27%)
Similarity:	106/238 - (44%)	Gaps:	31/238 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 ATFPWVVSVLDQRDWLFRYIGVGSLINPNVVLTAAHILN---GTTKYDLVVRAGEWDTSTTADQQ 98
            |:.|::.::     ::..:...||||:|..::||||.|:   ..||..:|:....::|:   ||.
Frog   368 ASHPYIAAL-----YIDNHFCGGSLISPCWIVTAAHCLDQRPNVTKISVVLGQSRFNTT---DQH 424

  Fly    99 HVDLEVLNIVSHEQFNRFNAENNMALL-------ILVSAFEMTANINLIPLYLQEAGIQKGSCFF 156
            .|.|.|...:.||::.....::::||:       :..|.|........:|...:.|...| .|..
Frog   425 TVTLLVEKYILHEKYYGDTLQHDIALVKVKSINGLCASEFSQFVQPICLPQQFKMAESTK-QCVV 488

  Fly   157 NGWGKVYLNSTDYPTVLKTVQVDLLSMGMCSS------RKLPIQQICGKGLE-GID-CSGDGGAP 213
            .|||..|..:..|...|:...:.::....|.|      |.|| ..:|...:| |:| |.||.|.|
Frog   489 AGWGHQYEGAEHYAFFLQEASMPIIPYTQCQSPSVHGDRMLP-GMLCAGFMEGGVDACQGDSGGP 552

  Fly   214 LVCRILTYPYKYAQVGIVNWLSQKPVENTFIVFTNVAGLLPWI 256
            |||.:   ..:....|:|:|.|....||...|:|.|.....||
Frog   553 LVCEV---DGRIELHGVVSWGSGCAEENKPGVYTAVTSYTDWI 592

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4259	NP_001259904.1	Tryp_SPc	39..259	CDD:238113	64/236 (27%)
CG4259	NP_001259904.1	Tryp_SPc	39..256	CDD:214473	62/234 (26%)
f12	XP_017947702.2	fn2	46..87	CDD:394995
		EGF_CA	95..129	CDD:238011
		KR	213..298	CDD:214527
		Tryp_SPc	359..595	CDD:238113	65/238 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910