DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4259 and LOC100491119

DIOPT Version :9

Sequence 1:	NP_001259904.1	Gene:	CG4259 / 33385	FlyBaseID:	FBgn0031389	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	XP_004916446.1	Gene:	LOC100491119 / 100491119	-ID:	-	Length:	512	Species:	Xenopus tropicalis

Alignment Length:	238	Identity:	66/238 - (27%)
Similarity:	113/238 - (47%)	Gaps:	26/238 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 FPWVVSVLDQRDWLFRYIGVGSLINPNVVLTAAH--ILNG-TTKYDLVVRAGEWDTSTTADQQHV 100
            :||.||:    .|..|::..||:|:...|::|||  :||| .|.....:.||....||     .:
Frog   286 WPWQVSL----RWDGRHMCGGSIISSQWVMSAAHCFVLNGFLTVSRWKIHAGSISLST-----GI 341

  Fly   101 DLEVLNIVSHEQFNRFNAENNMALL--ILVSAFEMTANINLIPLYLQEAGIQKGSCFFNGWGKVY 163
            ...|.||..:..::....:.::|||  .:..:|..|.....:|...|:..: ..:|:..|||.|.
Frog   342 AYSVRNIYYNGLYSLETNDYDVALLKTTVPMSFSDTTRPVCLPRAYQQFQV-TANCWIIGWGHVS 405

  Fly   164 LNSTDYPTVLKTVQVDLLSMGMCS-----SRKLPIQQICGKGLEG--IDCSGDGGAPLVCRILTY 221
            ......| ||:..:|.|:|..:|:     :.::..:.:|....:|  ..|.||.|.||||:   .
Frog   406 EGGQLSP-VLQEAKVQLISSQICNHSSNYAGQISPRMLCAGYPDGRADSCQGDSGGPLVCQ---E 466

  Fly   222 PYKYAQVGIVNWLSQKPVENTFIVFTNVAGLLPWIDYHLRLEA 264
            ...:.|||||:|.......|...|:||:..:|.|:.:.|::::
Frog   467 GGLWWQVGIVSWGEGCGRPNRPGVYTNLTEVLDWVYHRLQMDS 509

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4259	NP_001259904.1	Tryp_SPc	39..259	CDD:238113	65/231 (28%)
CG4259	NP_001259904.1	Tryp_SPc	39..256	CDD:214473	64/228 (28%)
LOC100491119	XP_004916446.1	SRCR_2	172..269	CDD:373897
LOC100491119	XP_004916446.1	Tryp_SPc	275..501	CDD:238113	64/228 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910