DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4259 and tmprss3

DIOPT Version :9

Sequence 1:	NP_001259904.1	Gene:	CG4259 / 33385	FlyBaseID:	FBgn0031389	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	XP_031752328.1	Gene:	tmprss3 / 100490444	XenbaseID:	XB-GENE-994580	Length:	483	Species:	Xenopus tropicalis

Alignment Length:	306	Identity:	81/306 - (26%)
Similarity:	127/306 - (41%)	Gaps:	70/306 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 FAFLTTLIISLVN-SQYFNYNQI---------RRETYGSNPR---------ATFPWVVSVLDQRD 50
            ||..|:|:..|:| |:|.:...:         .|.:|.|:.|         ..:||..|::.|
Frog   202 FAGQTSLLQQLINPSEYCSSGNVITLKCVVCGLRPSYTSSARIVGGNVSAVGQWPWQASLVFQ-- 264

  Fly    51 WLFRYIGV----GSLINPNVVLTAAHILNGTTKYDLVVRAGEW------DTSTTADQQHVDLEVL 105
                  ||    ||||.|..::||||.:     |||:.  .||      ..|..::.....:.|.
Frog   265 ------GVHLCGGSLITPQWIVTAAHCV-----YDLLY--PEWWRVQVGQVSQASESAQTAVPVQ 316

  Fly   106 NIVSHEQFNRFNAENNMALLILVSAFEMTANINLIPLYLQEAGIQKGS-CFFNGWGKVYLNSTDY 169
            .|:.|.::......|::||:.|.|.|....:|..|.|........:|. |:.:|||... ...|.
Frog   317 KIIYHSKYRSSTMANDIALIRLASPFTFNGSIQPICLPNYREDFPEGKICWISGWGATE-EGGDT 380

  Fly   170 PTVLKTVQVDLLSMGMCSSRKL------PIQQICGKGLE-GID-CSGDGGAPLVCRILTYPYKYA 226
            ...:....|.|:|..:|:::.:      | ..:|...|| |:| |.||.|.||.|.....   :.
Frog   381 SQTMDYAGVPLISNRVCNTKYIYGGVIKP-SMVCAGFLEGGVDTCQGDSGGPLACEDSNV---WK 441

  Fly   227 QVGIVNW-----LSQKPVENTFIVFTNVAGLLPWIDYHLRLEANFR 267
            .:|..:|     |..||.     |:|.::..|.||  |:::|...|
Frog   442 LMGTTSWGIGCALRYKPG-----VYTRISSFLDWI--HIQMEKEER 480

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4259	NP_001259904.1	Tryp_SPc	39..259	CDD:238113	66/243 (27%)
CG4259	NP_001259904.1	Tryp_SPc	39..256	CDD:214473	64/240 (27%)
tmprss3	XP_031752328.1	LDLa	96..128	CDD:197566
		SRCR_2	136..236	CDD:406055	8/33 (24%)
		Tryp_SPc	244..472	CDD:238113	66/254 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910