DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4259 and klkb1

DIOPT Version :9

Sequence 1:	NP_001259904.1	Gene:	CG4259 / 33385	FlyBaseID:	FBgn0031389	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	XP_002934450.3	Gene:	klkb1 / 100486524	XenbaseID:	XB-GENE-985051	Length:	629	Species:	Xenopus tropicalis

Alignment Length:	249	Identity:	59/249 - (23%)
Similarity:	94/249 - (37%)	Gaps:	46/249 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 FPWVVSV-LDQRDWLFRYIGVGSLINPNVVLTAAH------------ILNGTTKYDLVVRAGEWD 90
            :||.||: |.......::...||:|:...::||||            |.:|..|...:.::..:.
Frog   402 WPWQVSMHLRLTASYKKHACGGSIISNQWIVTAAHCFAMHPLPQMWIIYSGVVKLSNITQSTPFS 466

  Fly    91 TSTTADQQHVDLEVLNIVSHEQFNRFNAENNMALLILVSAFEMTANINLIPLYLQE-AGIQKGSC 154
                        |...|:.|..:.......::|||.|.:......:...|.|..:| ..:...||
Frog   467 ------------ETEQIIIHPHYTGAGNGTDIALLKLKTPISFNDHQKAICLPPREPTFVLPNSC 519

  Fly   155 FFNGWGKVYLNSTDYPTVLKTVQVDLLSMGMCSSR----KLPIQQICGKGLEG-ID-CSGDGGAP 213
            :..|||... .|.....:|:..:|..:|...|...    ::..:.:|.....| || |.||.|.|
Frog   520 WITGWGFTE-ESGSLANILQKAEVPQISTEECQGNYEQTRIDKKILCAGYKRGKIDSCKGDSGGP 583

  Fly   214 LVCRILTYPYKYAQVGIVNW-----LSQKPVENTFIVFTNVAGLLPWIDYHLRL 262
            |.|.:....|   ..||.:|     ...||.     |:|.|:....||..|.|:
Frog   584 LACVVDEIWY---LTGITSWGEGCARPGKPG-----VYTRVSEFTDWIIEHTRV 629

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4259	NP_001259904.1	Tryp_SPc	39..259	CDD:238113	57/244 (23%)
CG4259	NP_001259904.1	Tryp_SPc	39..256	CDD:214473	55/241 (23%)
klkb1	XP_002934450.3	APPLE	21..103	CDD:128519
		APPLE	110..193	CDD:128519
		APPLE	200..283	CDD:128519
		APPLE	290..373	CDD:128519
		Tryp_SPc	391..626	CDD:238113	57/244 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910