DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4259 and hgfac

DIOPT Version :9

Sequence 1:	NP_001259904.1	Gene:	CG4259 / 33385	FlyBaseID:	FBgn0031389	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	XP_002939269.3	Gene:	hgfac / 100485696	XenbaseID:	XB-GENE-940012	Length:	595	Species:	Xenopus tropicalis

Alignment Length:	247	Identity:	65/247 - (26%)
Similarity:	105/247 - (42%)	Gaps:	25/247 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 RRETYGSNPR--ATFPWVVSVLDQRDWLFRYIGVGSLINPNVVLTAAH-ILNGTTKYDLVVRAGE 88
            |....|.|..  .:.|||..:     ::..|...||||.|..|::||| ..:..:|..:.|..|:
Frog   349 RGRILGGNSALPGSHPWVAGI-----YIGNYFCAGSLIQPCWVVSAAHCFADSPSKSKIRVVLGQ 408

  Fly    89 WDTSTTADQQHVDLEVLNIVSHEQFNRFNAENNMALLILV-----SAFEMTANINLIPLYLQEAG 148
            ...:.|.|.... .||...:.:::::.|....:..:||.:     :..:.|..:..|.|....|.
Frog   409 HFFNQTTDVTQT-FEVERYIFYDKYSVFKRNEHDIVLIKLKRINNACAKKTQFVQTICLPDVSAP 472

  Fly   149 I-QKGSCFFNGWGKVYLNSTDYPTVLKTVQVDLLSMGMCSSRKLPIQQI-----CGKGLE-GID- 205
            . ....|...|||:::.:||:|...|:...|.|:....|||.::...:|     |....: .||
Frog   473 FADDHHCQIAGWGRMHEDSTEYAQNLQEAIVPLVPDNKCSSPEIYGAEISENMFCAGYFDCTIDS 537

  Fly   206 CSGDGGAPLVCRILTYPYKYAQVGIVNWLSQKPVENTFIVFTNVAGLLPWID 257
            |.||.|.||.|......|.:   |||:|.......|...|:|.|:..:.||:
Frog   538 CQGDSGGPLACEKDKISYLW---GIVSWGEGCGNHNKPGVYTKVSNYVDWIN 586

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4259	NP_001259904.1	Tryp_SPc	39..259	CDD:238113	62/233 (27%)
CG4259	NP_001259904.1	Tryp_SPc	39..256	CDD:214473	60/230 (26%)
hgfac	XP_002939269.3	FN2	52..98	CDD:238019
		EGF_CA	109..145	CDD:238011
		FN1	147..185	CDD:238018
		KR	235..319	CDD:294073
		Tryp_SPc	351..585	CDD:214473	62/242 (26%)
		Tryp_SPc	352..588	CDD:238113	64/244 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910