DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4259 and tmprss15

DIOPT Version :9

Sequence 1:	NP_001259904.1	Gene:	CG4259 / 33385	FlyBaseID:	FBgn0031389	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	XP_001919639.2	Gene:	tmprss15 / 100148042	ZFINID:	ZDB-GENE-091204-83	Length:	990	Species:	Danio rerio

Alignment Length:	262	Identity:	67/262 - (25%)
Similarity:	106/262 - (40%)	Gaps:	65/262 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 NQIRRETYGSN----------PRATFPWVVSVLDQRDWLFRYIGVGSLINPNVVLTAAHILNGTT 78
            ::|..||.|..          .|..:||:||:    .||..:....:||:...::||||.:.|..
Zfish   734 SKIIEETDGKKEGRVVGGQDAQRGAWPWMVSL----QWLGGHACGATLIDREWLITAAHCVYGRN 794

  Fly    79 KYDLVVRAGEWDTSTTADQQHVDLEVLN----------IVSHEQFNRFNAENNMALLILVSAFEM 133
                 |:...|   ......|...|.:|          ::.|:.:|:...|::.||:.|.:....
Zfish   795 -----VQLSNW---AAVLGLHAQFETINPNKQVFSVDQVIMHKHYNKRTKESDFALMHLKTPVSY 851

  Fly   134 TANINLIPLYLQEAG--IQKG-SCFFNGWGKVYLNSTDYPTVLKTVQVDLLSMGMCSSRKLP--- 192
            |..:.  |:.|.:.|  .::| .||..||| :...|.....||:...|.|||...| ...||
Zfish   852 TDYVQ--PICLPDPGAHFEEGRKCFIAGWG-LLSESGLKADVLQQAVVPLLSNTQC-QEWLPEYN 912

  Fly   193 --IQQIC-GKGLEGID-CSGDGGAPLVCR-----ILT-------------YPYKYAQVG-IVNWL 234
              .:.:| |....|:| |.||.|.||:|.     :|.             .|..||:|. .|:|:
Zfish   913 FTERMMCAGYAEGGVDTCQGDSGGPLMCEEEGHWVLVGATSFGIGCGRPQRPGAYARVSQFVDWV 977

  Fly   235 SQ 236
            ::
Zfish   978 AE 979

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4259	NP_001259904.1	Tryp_SPc	39..259	CDD:238113	62/237 (26%)
CG4259	NP_001259904.1	Tryp_SPc	39..256	CDD:214473	62/237 (26%)
tmprss15	XP_001919639.2	SEA	19..>89	CDD:279699
		LDLa	142..175	CDD:238060
		CUB	183..288	CDD:238001
		MAM	302..457	CDD:279023
		MAM	302..457	CDD:99706
		CUB	477..586	CDD:238001
		LDLa	596..630	CDD:238060
		SRCR_2	653..728	CDD:295335
		Tryp_SPc	747..977	CDD:214473	62/245 (25%)
		Tryp_SPc	748..980	CDD:238113	63/248 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910