Sequence 1: | NP_001259898.1 | Gene: | Su(dx) / 33379 | FlyBaseID: | FBgn0003557 | Length: | 949 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_001034568.1 | Gene: | AREL1 / 9870 | HGNCID: | 20363 | Length: | 823 | Species: | Homo sapiens |
Alignment Length: | 576 | Identity: | 164/576 - (28%) |
---|---|---|---|
Similarity: | 261/576 - (45%) | Gaps: | 107/576 - (18%) |
- Green bases have known domain annotations that are detailed below.
Fly 417 NTRKTTWQRPNSERLMHFQHWQGQRAHVVSQGNQRYLYSQQQQQPTAVTAQVTQDDEDALGPLPD 481
Fly 482 GWEKKIQSDNRVY-FVNHKN--------RTTQWE------DPRTQGQEVS----------LINEG 521
Fly 522 PLPPGWEIRYTAAGERFFVDHNTRRTTFEDPRPGAPKGAKGVYGVPRAYERSFRWKLSQF-RYLC 585
Fly 586 QSNALPSHIKIT--VTRQTLFEDSYHQIMRLPAYELRRRLYIIFRGEEGLDYGGVSREWFFLLSH 648
Fly 649 EVLNPMYCLFEYANKNNYSLQINPASYVNPD-----HLQYFKFIGRFIAMALY-------HGRFI 701
Fly 702 YSGFTMPFYKRMLNKKLTIKDIETIDPEFYNSLI-WVKDNNIDECGLELWFSVD-FEVLGQIIH- 763
Fly 764 HELKENGEKERVTEENKEEYITLMTEWRMTRGIEQQTKTFLEGFNEVVPLEWLKYFDERELELIL 828
Fly 829 CGMQDVDVEDWQRNTIY--RHYNRNSKQVVWFWQFVRETDNEKRARLLQFVTGTCRVPVGGFAEL 891
Fly 892 MGSNGPQRFCIEKVGKETWLPRSHTCFNRLDLPPYKSYDQLVEKLTFAIEE-TEGF 946 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
Su(dx) | NP_001259898.1 | C2_E3_ubiquitin_ligase | 48..173 | CDD:175988 | |
WW | 364..396 | CDD:197736 | |||
WW | 397..426 | CDD:278809 | 3/8 (38%) | ||
WW | 478..509 | CDD:197736 | 7/45 (16%) | ||
WW | 522..554 | CDD:197736 | 6/31 (19%) | ||
HECTc | 594..946 | CDD:238033 | 123/371 (33%) | ||
HECTc | 620..946 | CDD:214523 | 116/343 (34%) | ||
AREL1 | NP_001034568.1 | Filamin | 52..158 | ||
Filamin | 56..154 | CDD:395505 | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 315..345 | 12/58 (21%) | |||
Interaction with SOCS2. /evidence=ECO:0000269|PubMed:31578312 | 483..789 | 100/317 (32%) | |||
HECTc | 486..820 | CDD:214523 | 116/345 (34%) | ||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_COG5021 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
2 | 1.810 |