Protein Alignment Su(dx) and kmr

DIOPT Version :10

• Sequence 1: NP_476753.1
• Gene: Su(dx) / 33379
• FlyBaseID: FBgn0003557
• Length: 949
• Species: Drosophila melanogaster
• Sequence 2: XP_061508792.1
• Gene: kmr / 5667264
• VectorBaseID: AGAMI1_001097
• Length: 2966
• Species: Anopheles gambiae
• Alignment Length: 637
• Identity: 128/637 - (20%)
• Similarity: 203/637 - (31%)
• Gaps: 229/637 - (35%)

  Fly     2 ADGNG--LPAGAASGGMEAGQTVNGAGSASPTPTSSSGAGASGSANQGYHQLSVTIEEASL---- 60
            |.|.|  |.:..:|||.::    :|:.........:||.|:|.|:..|...:|...:..|:
Mosquito   665 AGGTGTELLSSDSSGGPQS----HGSNDTMKLIQQASGNGSSSSSGGGGGGVSALNDSMSMPQPL 725

  Fly    61 -----------RNNGFLKPNPYVELLIDSKSKRKTDLVKNSYLPKWNEEFTVLIT---------- 104
                       .:.|:..|:|...:|.|    |...:|:...:         |.|
Mosquito   726 YANAPPKPRRVNDGGYSSPSPEHTMLHD----RYDQMVQQQQM---------LATGGPFPPGAVG 777

  Fly   105 -----PNSTLHFKVLDHSSFRKDAMLGERIINLAHILQHYNGRCEFLELTIDLFVTSKSDNRQTK 164
                 ||..:   ||  .|.|..|.|      .||.:.....|.|     .||::....:.:|.:
Mosquito   778 GGSGPPNGGM---VL--GSSRTPAAL------TAHAIYGDPKRIE-----RDLYIQKLIEQQQQQ 826

  Fly   165 SGELVAILNGLKLDMSKLQIQPVAGQQNG--------------------------------NPPV 197
            ..:    ||..|....:.|.|...|.|:.                                .||.
Mosquito   827 QQK----LNASKQQQQQQQQQQQQGMQSSPMHGGGVLRSGGGAGTNPFLYPSNDRRTPDTYGPPN 887

  Fly   198 QAVNPSVVSDAAAGRSCMIYGGVRARMRLRSSSGNSNGGETRS---PLPNGGGDHRRSTQAPPVW 259
            .|::|..:||...     ||     .:.:.|.|..:|..|..:   .:|.||..::|.:
Mosquito   888 SAIDPKHMSDYED-----IY-----NLTMLSKSLPANAMEAAAGGGGVPAGGTTYKRPS------ 936

  Fly   260 EQQQQQSQNQQQPLRMV-NGS-----GAAVPQTAPYPQQPPAPALARPLTQVYGALPENTQPAAV 318
                       .|||.. ||:     |||:.....:..|.|..|         |..|::.|..|.
Mosquito   937 -----------SPLRYEGNGAFPAYMGAAIYNAGQFEHQSPGAA---------GQHPQHAQMRAR 981

  Fly   319 YLPAGGGAAVGPPGVAGP------------PIEQPGVGLPVSQSTDPQLQTQPADDEPLPAGWEI 371
            .:         ||.:..|            |:.|...|:     ||   :..|....|.|.. .:
Mosquito   982 PI---------PPSIPRPHSADFLDYEARHPMNQAAGGV-----TD---EPSPVHRTPRPKS-SL 1028

  Fly   372 RLDQYGRRYYVDHNTRSTYWEK----------PTPLPPGWEIRK----DGRGRVYYVDHNTRKTT 422
            .:::....||.   :.::|.||          .|..|.....||    |.:|  .:|.....:..
Mosquito  1029 DINRTPDHYYY---SEASYAEKMRLQSASYLQRTNNPGAGASRKQRSDDMQG--LFVSGTMPRDG 1088

  Fly   423 WQRPNSERLMHFQ----------HWQGQ------------------RAHVVSQGNQRYLYSQQQQ 459
            ..|..|.::|..|          |...|                  |..|.|...|.....||:|
Mosquito  1089 LYRSGSGKIMQLQASGQQGEDYPHGGSQSMPRPSATDHRTGGTGQGRPTVSSLKKQGTAQQQQEQ 1153

  Fly   460 QPTAVTAQVTQDDEDALGPLPDGWEKKIQSDNRVYFVNHKNRTTQWEDPRTQ 511
            ...:.:|::.:.:||:  .|.||..|:.:|..|:  :..|.|..|  .|.|:
Mosquito  1154 FARSASARLPRKEEDS--SLRDGERKREESMKRL--LEWKQRMLQ--SPLTK 1199

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Su(dx)	NP_476753.1	C2_E3_ubiquitin_ligase	48..173	CDD:175988	26/154 (17%)
		WW	364..396	CDD:197736	7/41 (17%)
		HUL4	<395..946	CDD:227354	34/149 (23%)
kmr	XP_061508792.1	None