DRSC/TRiP Functional Genomics Resources

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Protein Alignment Su(dx) and yki

DIOPT Version :9

Sequence 1:NP_001259898.1 Gene:Su(dx) / 33379 FlyBaseID:FBgn0003557 Length:949 Species:Drosophila melanogaster
Sequence 2:NP_001350857.1 Gene:yki / 37851 FlyBaseID:FBgn0034970 Length:418 Species:Drosophila melanogaster


Alignment Length:431 Identity:110/431 - (25%)
Similarity:159/431 - (36%) Gaps:137/431 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly   143 CEFLELTIDLF--VTSKSDNRQT-----------------KSGELVAILNGLKLDMSKLQIQPVA 188
            |.|...||..|  :|:.|.:..|                 ||..||..:|               
  Fly    12 CSFRLYTISAFYMLTTMSASSNTNSLIEKEIDDEDMLSPIKSNNLVVRVN--------------- 61

  Fly   189 GQQNGNPPVQAVNPSVVSDAAAGRSCMIYGGVRARMRLRSSSGNSNGGETRSPLPNG-----GGD 248
              |:.:..:||:..||::...|.|.      ::..:|:|.             |||.     ...
  Fly    62 --QDTDDNLQALFDSVLNPGDAKRP------LQLPLRMRK-------------LPNSFFTPPAPS 105

  Fly   249 HRRSTQAPPVWEQQQQQSQN-------QQQPLRMVNGSG--AAVP--QTAPYPQQP--------- 293
            |.|:..|...::...|.|.|       .|||    :|..  ||:|  |..|.||..         
  Fly   106 HSRANSADSTYDAGSQSSINIGNKASIVQQP----DGQSPIAAIPQLQIQPSPQHSRLAIHHSRA 166

  Fly   294 -PAPAL------ARPLTQVYGALPENTQPAAVYLPAG-----GGAAVGPPGV-AGPPIEQPGVGL 345
             .:||.      .|..:....|...|..|::...|||     ..|...|.|. |...|:...:..
  Fly   167 RSSPASLQQNYNVRARSDAAAANNPNANPSSQQQPAGPTFPENSAQEFPSGAPASSAIDLDAMNT 231

  Fly   346 PVSQSTDPQLQT----QPADDEPLPAGWEIRLD-QYGRRYYVDHNTRSTYWEKPTPLPPGWEIRK 405
            .:||.....:||    |.:.|...|    |:|: |.|                  .||||||..|
  Fly   232 CMSQDIPMSMQTVHKKQRSYDVISP----IQLNRQLG------------------ALPPGWEQAK 274

  Fly   406 DGRGRVYYVDHNTRKTTWQRPNSERLMHFQHWQGQRAHVVSQGNQRYLYSQQQQQPTAVTAQVTQ 470
            ...|::||::|.|:.|.|:.|      ..|:.|.|:..:..:..|..:....:|..|:..|    
  Fly   275 TNDGQIYYLNHTTKSTQWEDP------RIQYRQQQQILMAERIKQNDVLQTTKQTTTSTIA---- 329

  Fly   471 DDEDALGPLPDGWEKKIQSDNRVYFVNHKNRTTQWEDPRTQ 511
               :.|||||||||:.:.....:||:||.:|||.|.|||.|
  Fly   330 ---NNLGPLPDGWEQAVTESGDLYFINHIDRTTSWNDPRMQ 367

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Su(dx)NP_001259898.1 C2_E3_ubiquitin_ligase 48..173 CDD:175988 12/48 (25%)
WW 364..396 CDD:197736 5/32 (16%)
WW 397..426 CDD:278809 14/28 (50%)
WW 478..509 CDD:197736 16/30 (53%)
WW 522..554 CDD:197736
HECTc 594..946 CDD:238033
HECTc 620..946 CDD:214523
ykiNP_001350857.1 HUL4 <261..>404 CDD:227354 45/138 (33%)
WW 266..295 CDD:395320 14/28 (50%)
WW 335..364 CDD:395320 14/28 (50%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5021
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.810

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