DRSC/TRiP Functional Genomics Resources

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Protein Alignment Su(dx) and Magi

DIOPT Version :9

Sequence 1:NP_001259898.1 Gene:Su(dx) / 33379 FlyBaseID:FBgn0003557 Length:949 Species:Drosophila melanogaster
Sequence 2:NP_001286661.1 Gene:Magi / 37403 FlyBaseID:FBgn0034590 Length:1202 Species:Drosophila melanogaster


Alignment Length:386 Identity:91/386 - (23%)
Similarity:132/386 - (34%) Gaps:142/386 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly   186 PVAGQQ-----NGNPPVQAVNPSVVSDAAAGRSC----MIYGGVRARMRLRSSSGNSNGGETRSP 241
            |||...     |||   ..:|.|:.:.::...:|    :..||....|...|.:.:|.|.:.   
  Fly    83 PVAAATSFATFNGN---SNLNSSLANGSSRKFNCSRDNVDDGGDAGEMAAASQTLSSAGTDV--- 141

  Fly   242 LPNGGGDHRRSTQAPPVWEQQQQQSQNQQQPLRMVNG--SGAAVPQTAPYPQQPPAPALARPLTQ 304
            :.||.| |...|...                    ||  ||...|....:.:.||.|||.:..:.
  Fly   142 VGNGSG-HGNGTVTG--------------------NGEKSGGLAPPGGHHLRPPPPPALKKSASA 185

  Fly   305 VYGALPENTQPAAVY------------------LPAG--------GGAAVGPPGVAGPPI----- 338
            |.|........|::.                  ||:.        ||||.|.   .|||.     
  Fly   186 VIGNSASREDVASLSGTSSLNSQMSVHNQFISGLPSNGIGSNGVHGGAATGR---GGPPNSILKG 247

  Fly   339 ---------------------EQPGVGLPVSQSTDPQLQTQPADDE------PLPAGWEIRLDQY 376
                                 .:.|||       |.|.|...:.|:      |||..||....:.
  Fly   248 SKENLLQNTYYNGETGDSSLGSECGVG-------DVQHQNHESHDDPGDGLGPLPPKWETAYTER 305

  Fly   377 GRRYYVDHNTRSTYWEKP---------------TPLPPGWEIRKDGRGRVYYVDHNTRKTTWQRP 426
            |..|::||||.:::|..|               ..||.|||..:|....:|::||..|:|.::.|
  Fly   306 GELYFIDHNTGTSHWLDPRLSKYQKKSLEDCCEDELPYGWEKIEDSMYGMYFIDHVNRRTQYENP 370

  Fly   427 NSERLMHFQHWQGQRAHVVSQGNQRYLYSQQQQQ------PTAVT-------AQVTQDDED 474
            ..|        ..:||...||..|:....|||.|      |||::       |:..:.:||
  Fly   371 VLE--------AKRRAAEQSQQQQQMQQQQQQMQEQRSKTPTALSETMPTEAAEAHEQEED 423

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Su(dx)NP_001259898.1 C2_E3_ubiquitin_ligase 48..173 CDD:175988
WW 364..396 CDD:197736 13/46 (28%)
WW 397..426 CDD:278809 11/28 (39%)
WW 478..509 CDD:197736
WW 522..554 CDD:197736
HECTc 594..946 CDD:238033
HECTc 620..946 CDD:214523
MagiNP_001286661.1 WW 294..323 CDD:278809 11/28 (39%)
WW 342..372 CDD:238122 11/29 (38%)
PDZ 443..534 CDD:214570
DegQ <455..534 CDD:223343
PDZ_signaling 606..668 CDD:238492
PDZ 925..1011 CDD:214570
PDZ_signaling 1029..1110 CDD:238492
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5021
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.810

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