DRSC/TRiP Functional Genomics Resources

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Protein Alignment Su(dx) and Hace1

DIOPT Version :9

Sequence 1:NP_001259898.1 Gene:Su(dx) / 33379 FlyBaseID:FBgn0003557 Length:949 Species:Drosophila melanogaster
Sequence 2:XP_006256657.1 Gene:Hace1 / 361866 RGDID:1306114 Length:916 Species:Rattus norvegicus


Alignment Length:347 Identity:149/347 - (42%)
Similarity:210/347 - (60%) Gaps:4/347 - (1%)


- Green bases have known domain annotations that are detailed below.


  Fly   596 ITVTRQTLFEDSYHQIMRLPAYELRRRLYIIFRGEEGLDYGGVSREWFFLLSHEVLNPMYCLFEY 660
            :.|.|.::|..|...:.:....:|::.:.:.|.||||:.. ||.||||.:||:|::||.|.||. 
  Rat   562 LLVHRDSIFRSSCEIVSKANCAKLKQGIAVRFHGEEGMGQ-GVVREWFDILSNEIVNPDYALFT- 624

  Fly   661 ANKNNYSLQINPASYVNPDHLQYFKFIGRFIAMALYHGRFIYSGFTMPFYKRMLNKKLTIKDIET 725
            .:.:..:.|.|..||||||||.||:|.|:.:.:||.|.:.:...||..|||.:|...:..:|:.:
  Rat   625 QSADGTTFQPNSNSYVNPDHLNYFRFAGQILGLALNHRQLVNIYFTRSFYKHILGIPVNYQDVAS 689

  Fly   726 IDPEFYNSLIWVKDNNIDECGLELWFSVDFEVLGQIIHHELKENGEKERVTEENKEEYITLMTEW 790
            ||||:..:|.|:.||:|.:.||||.|||:.:|.|.:....||..|....||:.||.||:.|:||.
  Rat   690 IDPEYAKNLQWILDNDISDLGLELTFSVETDVFGAMEEVPLKPGGGSILVTQNNKAEYVQLVTEL 754

  Fly   791 RMTRGIEQQTKTFLEGFNEVVPLEWLKYFDERELELILCGMQDVDVEDWQRNTIYRH-YNRNSKQ 854
            ||||.|:.|...||:||:..:|...::.|||.||||:|.||.::||.||.:||.|.. |.|....
  Rat   755 RMTRAIQPQINAFLQGFHMFIPPSLIQLFDEYELELLLSGMPEIDVNDWIKNTEYTSGYEREDPV 819

  Fly   855 VVWFWQFVRETDNEKRARLLQFVTGTCRVPVGGFAELMGSNGPQRFCIEKVG-KETWLPRSHTCF 918
            :.|||:.|.:...|:|..|||||||:.|||.||||.:||.:|.|.|.|..|. ....||.|.||.
  Rat   820 IQWFWEVVEDMTQEERVLLLQFVTGSSRVPHGGFANIMGGSGLQNFTIAAVPYTPNLLPTSSTCI 884

  Fly   919 NRLDLPPYKSYDQLVEKLTFAI 940
            |.|.||.|.|.:.|.::|..|:
  Rat   885 NMLKLPEYPSKEILKDRLLVAL 906

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Su(dx)NP_001259898.1 C2_E3_ubiquitin_ligase 48..173 CDD:175988
WW 364..396 CDD:197736
WW 397..426 CDD:278809
WW 478..509 CDD:197736
WW 522..554 CDD:197736
HECTc 594..946 CDD:238033 149/347 (43%)
HECTc 620..946 CDD:214523 144/323 (45%)
Hace1XP_006256657.1 ANK repeat 66..95 CDD:293786
ANK 66..93 CDD:197603
Ank_2 69..194 CDD:289560
ANK 92..217 CDD:238125
ANK repeat 97..128 CDD:293786
ANK repeat 130..161 CDD:293786
Ank_2 135..222 CDD:289560
ANK repeat 163..194 CDD:293786
ANK repeat 196..221 CDD:293786
Ank_4 199..249 CDD:290365
HECTc 561..910 CDD:238033 149/347 (43%)
HECTc 586..909 CDD:214523 144/323 (45%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5021
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000080
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
43.810

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