Protein Alignment Su(dx) and CG42797

DIOPT Version :9

• Sequence 1: NP_001259898.1
• Gene: Su(dx) / 33379
• FlyBaseID: FBgn0003557
• Length: 949
• Species: Drosophila melanogaster
• Sequence 2: NP_572574.2
• Gene: CG42797 / 31905
• FlyBaseID: FBgn0261931
• Length: 1426
• Species: Drosophila melanogaster
• Alignment Length: 1147
• Identity: 312/1147 - (27%)
• Similarity: 465/1147 - (40%)
• Gaps: 314/1147 - (27%)

  Fly    55 IEEASLRNNGFLKPNPYVELLIDSKSKRKTDLVKNSYLPKWNEEFTVLITPNSTLHFKVLDHSSF 119
            :.|...:.:|....:|.....:..|...|..:..:||:   |...|..:..:.:..|.....||.
  Fly   336 LAEEMAQGSGSSNNSPLATPPVRFKPLLKKKIGPDSYI---NTISTQKVPVHQSYEFPTFPSSSA 397

  Fly   120 RKDAMLGERIINLAHILQH-------YNGRCEFLE--LTIDLFVTSKSDNRQTKSGELVAILNGL 175
            ...:......:...::.||       .||:....|  .:..|.::.|.. |...||......:.|
  Fly   398 VGSSSSSPNSLQFPYLRQHRPLTRALSNGKASSSEEQASPRLLLSPKRP-RSPPSGCSTRSASPL 461

  Fly   176 KLDMSKLQIQPVAGQQNGNPPVQAVNPSVVSDAAAGRSCMIYGGVRARMRLRSSSG-----NSNG 235
            .:.:|..|..|..|:..|.....||.|...:          :.|.|.:.||....|     .:.|
  Fly   462 DISLSPEQHSPTRGRGVGGALQDAVPPGTPT----------FHGQRPQQRLLKRVGGGAGAGATG 516

  Fly   236 GETRSPL--PNGGGDHRR---------------------------STQAPPVWEQQQQQSQNQQQ 271
            |.|.|||  |.....|.|                           |:|...::.|...|.|.|:|
  Fly   517 GATGSPLVCPPTPTHHARRHARLQAVTANSSLASGGAIPSDPPAVSSQLDYIYLQDGGQEQGQEQ 581

  Fly   272 PLRMVNGSGAAVPQTAPYPQQPPAPALARPLTQVYGALPENTQPAAVYLPAGGGAAVGPPGVAGP 336
            ...:|:.|...:|                       ::||.:..||    |...||     .||.
  Fly   582 SDEVVHISSTRLP-----------------------SIPERSAAAA----AAAAAA-----AAGA 614

  Fly   337 PIEQPGVGLPVSQSTDPQLQTQPADDEPLPAGWEIRLDQYGRRYYVDHNTRSTYWEKPTPLPPGW 401
            .:.:||.| .||.|:......:|    |||..||.|:|.:||.:|:||.||:|.|::|...|.|.
  Fly   615 ALMEPGTG-TVSGSSGAGAAGEP----PLPPAWEARMDSHGRIFYIDHTTRTTSWQRPGAAPSGG 674

  Fly   402 ---------------------EIRKDGRGRVYY-----VDHNTRKTT----------------WQ 424
                                 .|..:.|....|     .:.|...|.                ..
  Fly   675 PAGREQHHRQQLDRRYQSIRRTITNESRAAQLYNLPTSANSNANSTAPAAPPPATAIHPAILMLC 739

  Fly   425 RPNSERLMH-------FQHWQGQRAHVVSQGN------QRYLYSQQQQQPTAVTAQVTQDDEDAL 476
            ||:...|:|       ..:......|:|.:..      |||.|::.........||::::
  Fly   740 RPDFYSLLHTNEAALAIYNRNAALKHMVMRIRRDPPCFQRYQYNKDLVALVNTFAQMSRE----- 799

  Fly   477 GPLPDGWEKKIQSDNRVYFVNHKNRTTQWEDPR-------------TQGQEVSLIN-------EG 521
              ||..||.|:....:.:|::|::|.|.:.|||             ...|:.|.:.       :|
  Fly   800 --LPSCWETKLDQSGKQFFIDHQHRRTSFMDPRLPVECPRVVRHRQQHSQQQSSVGYYYPDLVDG 862

  Fly   522 ----------------------PLPP--------------------------------------- 525
                                  ||||
  Fly   863 NCLSATSGHINASPASSVSGVPPLPPPRPSSSSSSSRSSHGHGHNCNTTSAISCALNADRSAYGA 927

  Fly   526 -----------GWEIRYTAAGERFFV----------------DHNTRR----------------- 546
                       |:|....|..|:...                .|...|
  Fly   928 AGMASAGATAAGYEDVPIAYNEKVIAFLRQPNILEILRERQGQHTMSRQLREKINILRVEGVPAL 992

  Fly   547 -------------TTFEDPRPG-------APKGAKGVYG-----VPRAYERSFRWKLSQFRYLCQ 586
                         :.||....|       :|:|:..:..     .|..:.|.|..||..|....:
  Fly   993 ERLGHDLQLTILLSLFEQEIMGFVPIEERSPQGSPVLNSRMPQRAPPPFRRDFEAKLRSFYRKLE 1057

  Fly   587 SNAL---PSHIKITVTRQTLFEDSYHQIMRLPAYELRR-RLYIIFRGEEGLDYGGVSREWFFLLS 647
            |...   |..:|:.:.|..|.||::.:||.....:|:| ||.:::..||||||||.|||:|||||
  Fly  1058 SKGYGQGPHKLKLHIRRSHLLEDAFRRIMSANKKDLQRGRLAVLWDTEEGLDYGGPSREFFFLLS 1122

  Fly   648 HEVLNPMYCLFEYANKNNYSLQINPAS-YVNPDHLQYFKFIGRFIAMALYHGRFIYSGFTMPFYK 711
            .|:.||.|.||||:..:.|::|::|.| :|:..| .:|:|.||.:.:||.|...:.:.||.||||
  Fly  1123 RELFNPYYGLFEYSANDTYTVQVSPLSAFVDNCH-DWFRFSGRVLGLALVHQYLLDAFFTRPFYK 1186

  Fly   712 RMLNKKLTIKDIETIDPEFYNSLIWVKDNNIDE-CGLELWFSVDFEVLGQIIHHELKENGEKERV 775
            .:|...:.:.|:|::|.||:.||.|::||:|.. ..|.|.|.|..|:||.::..|||..|:...:
  Fly  1187 ALLRLPVALSDLESLDNEFHQSLQWIRDNDIGTGVDLGLTFCVTEELLGSVVDRELKPGGKNIII 1251

  Fly   776 TEENKEEYITLMTEWRMTRGIEQQTKTFLEGFNEVVPLEWLKYFDERELELILCGMQDVDVEDWQ 840
            .|:||:||:..|.:||:.||:::||::.:.||.||:....:..||.|||||::.|..::|..||:
  Fly  1252 NEKNKKEYLERMIKWRLERGVQEQTESLVRGFYEVIDSRLVSVFDARELELVIAGTAEIDTNDWR 1316

  Fly   841 RNTIYRH-YNRNSKQVVWFWQFVRETDNEKRARLLQFVTGTCRVPVGGFAELMGSNGPQRFCIEK 904
            .||.||. |:.|.:.:|||||.:....||:|.|||||||||..:|..||:.|.||.||:||||||
  Fly  1317 LNTEYRSGYHDNHQVIVWFWQVIERFSNEQRLRLLQFVTGTSSIPYEGFSALRGSTGPRRFCIEK 1381

  Fly   905 VGKETWLPRSHTCFNRLDLPPYKSYDQLVEKLTFAIEETEGF 946
            .||...|||:||||||||||||.:.:.|.|||..|:|||..|
  Fly  1382 WGKPNALPRAHTCFNRLDLPPYPTPELLYEKLLLAVEETNTF 1423

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Su(dx)	NP_001259898.1	C2_E3_ubiquitin_ligase	48..173	CDD:175988	22/126 (17%)
		WW	364..396	CDD:197736	17/31 (55%)
		WW	397..426	CDD:278809	7/70 (10%)
		WW	478..509	CDD:197736	10/30 (33%)
		WW	522..554	CDD:197736	12/127 (9%)
		HECTc	594..946	CDD:238033	166/355 (47%)
		HECTc	620..946	CDD:214523	158/329 (48%)
CG42797	NP_572574.2	WW	638..667	CDD:278809	15/28 (54%)
		HECTc	1068..1424	CDD:238033	167/357 (47%)
		HECTc	1092..1423	CDD:214523	159/331 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45447001
Domainoid	1	1.000	47	1.000	Domainoid score	I4528
eggNOG	1	0.900	-	-		E1_COG5021
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000080
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11254
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.840