Protein Alignment Su(dx) and Trip12

DIOPT Version :9

• Sequence 1: NP_001259898.1
• Gene: Su(dx) / 33379
• FlyBaseID: FBgn0003557
• Length: 949
• Species: Drosophila melanogaster
• Sequence 2: XP_038939619.1
• Gene: Trip12 / 316575
• RGDID: 1306607
• Length: 2074
• Species: Rattus norvegicus
• Alignment Length: 1185
• Identity: 262/1185 - (22%)
• Similarity: 404/1185 - (34%)
• Gaps: 411/1185 - (34%)

  Fly    23 NGAGSASPTPTSSSG---AGASGSANQG----YH------------QLSVTIEEASLRNNGFLKP 68
            ||:||...|..:|||   |..:.||:.|    .|            :||..::...|...|..:|
  Rat  1028 NGSGSLGSTTPASSGTATAATNASADLGSPSLQHSRDDSLDLSPQGRLSDVLKRKRLPKRGPRRP 1092

  Fly    69 N---PYVELLID--SKSKRKTDLVKNSYL----PK-WN----EEFTVLITPNSTLHFKVLDHSSF 119
            .   |..:..:|  :||...|...|:|:|    || |.    :..:..|.|..|.....|..::
  Rat  1093 KYSPPRDDDKVDNQAKSPTTTQSPKSSFLASLNPKTWGRLSAQSNSNNIEPARTAGVSGLARAA- 1156

  Fly   120 RKDAMLGER------IINLAH--------------------ILQHYNGRCEFLELTID------- 151
            .||.:...|      |...||                    :||......|.|.|.:|
  Rat  1157 SKDTISNNREKIKGWIKEQAHKFVERYFSSENMDGSNPALNVLQRLCAATEQLNLQVDGGAECLV 1221

  Fly   152 --------------------------LFVTSKSDNRQTKSGELVAILNGLKLDMSKLQIQPVAGQ 190
                                      |::||||: :...|.|:     .||..:......|:.|:
  Rat  1222 EIRSIVSESDVSSFEIQHSGFVKQLLLYLTSKSE-KDAVSREI-----RLKRFLHVFFSSPLPGE 1280

  Fly   191 QNGNPPVQAVNP-------SVVSDAAAGRSCMIYGGVRARMRLRSSSGNSNGGETRSPLPNGGGD 248
            :    ||..|.|       ::|.......|.|....|:..   ...|||.:||..         .
  Rat  1281 E----PVGRVEPVGHAPLLALVHKMNNCLSQMEQFPVKVH---DFPSGNGSGGSF---------S 1329

  Fly   249 HRRSTQAPPVWEQQQQQSQNQQQPLRMVNGSGAAVPQTAPYPQQPPAPALARPLTQV-------- 305
            ..|.:||...:...|.:.|.|:.            |..|...|....|....||..|
  Rat  1330 LNRGSQALKFFNTHQLKCQLQRH------------PDCANVKQWKGGPVKIDPLALVQAIERYLV 1382

  Fly   306 ------YGALPENTQP--------------AAVYLPAGG---------GAAVGPPGVAGPPIEQP 341
                  ||.:.|:.:.              ||.:|.:|.         |..:.|..:.
  Rat  1383 VRGIFRYGRVREDDEDSDDDGSDEEIDESLAAQFLNSGNVRHRLQFYIGEHLLPYNMT------- 1440

  Fly   342 GVGLPVSQ-STDPQLQTQPADDEPLPAG----WEIRLDQYGRRYYVDHNTRS-TYWEKPTPLPPG 400
             |...|.| |...:.:.:..|||..|.|    |                |:: |.|.||
  Rat  1441 -VYQAVRQFSVQAEDERESTDDESNPLGRAGIW----------------TKTHTIWYKP------ 1482

  Fly   401 WEIRKD----------GRGR---------------------------------VYYVDHNTRKTT 422
              :|:|          .|||                                 ||.:.......|
  Rat  1483 --VREDEESSKDCVGGKRGRAQTAPTKTSPRNAKKHDELWHDGVCPSVANPLEVYLIPTPPENIT 1545

  Fly   423 WQRPNSE-----RLMH--FQHWQGQRAHVVSQGNQRYLYSQQQQQPTAVTAQVTQDDEDALGPLP 480
            ::.|:.:     |::|  .::|.             |||.      .|:..::....|
  Rat  1546 FEDPSLDVILLLRVLHAISRYWY-------------YLYD------NAMCKEIIPTSE------- 1584

  Fly   481 DGWEKKIQSDNRVYFVNHK-----NRTTQWEDPRTQGQEVSLINEGPLPPGWEIRYTAAGER--F 538
                          |:|.|     ||  |.:||       .:|..|.:|. |   .|..|:.  |
  Rat  1585 --------------FINSKLTAKANR--QLQDP-------LVIMTGNIPT-W---LTELGKTCPF 1622

  Fly   539 FVDHNTRRTTFEDPRPGAPKGAKGVYGVPRAYERSFRWKLSQFRYLCQSNALPSHI-------KI 596
            |...:||:..|              |......:|:.:..|.....:.||::..|.:       |.
  Rat  1623 FFPFDTRQMLF--------------YVTAFDRDRAMQRLLDTNPEINQSDSQDSRVAPRLDRKKR 1673

  Fly   597 TVTRQTLFEDSYHQIMRLPAYELRRRLYIIFRGEEGLDYGGVSREWFFLLSHEVLNPMYCLF--E 659
            ||.|:.|.:.:...:..|.:  .|..|.|.:..|.|... |.:.|::.|:|.|:......|:  |
  Rat  1674 TVNREELLKQAESVMQDLGS--SRAMLEIQYENEVGTGL-GPTLEFYALVSQELQRADLGLWRGE 1735

  Fly   660 YANKNNYSLQINPASYV---------------NPDHL----QYFKFIGRFIAMALYHGRFIYSGF 705
            ....:|.........|:               .|.|:    ..|:|:|:.:|.|:...|.:....
  Rat  1736 EVTLSNPKGSQEGTKYIQNLQGLFALPFGRTAKPAHIAKVKMKFRFLGKLMAKAIMDFRLVDLPL 1800

  Fly   706 TMPFYKRMLNKK--LTIKDIETIDPEFYNSLIWVKD-------------------------NNID 743
            .:||||.||.::  ||..|:..|||....|:..::|                         ..::
  Rat  1801 GLPFYKWMLRQETSLTSHDLFDIDPVVARSVYHLEDIVRQKKRLEQDKSQTKESLQYALETLTMN 1865

  Fly   744 ECGLELWFSVDFEVLGQIIHHELKENGEKERVTEENKEEYITLMTEWRMTRGIEQQTKTFLEGFN 808
            .|.:| ...:||.:.| ..:.|||:.|:...||..|.|||:.|:..|.:..|:.:|..:|.:||.
  Rat  1866 GCSVE-DLGLDFTLPG-FPNIELKKGGKDIPVTIHNLEEYLRLVIFWALNEGVCRQFDSFRDGFE 1928

  Fly   809 EVVPLEWLKYFDERELELILCGMQDVDVEDWQRNTIYR-----H-YNRNSKQVVWFWQFVRETDN 867
            .|.||..|:||...||:.:|||.:   .:.|...|:..     | |..:|:.|.:.::.:...||
  Rat  1929 SVFPLSHLQYFYPEELDQLLCGSK---ADTWDAKTLMECCRPDHGYTHDSRAVKFLFEILSSFDN 1990

  Fly   868 EKRARLLQFVTGTCRVPVGGFAELMGSNGPQRFCIEKVGKET-----WLPRSHTCFNRLDLPPYK 927
            |::...||||||:.|:|||||..|    .|....:.|..:.|     :||...||.|.|.||.|.
  Rat  1991 EQQRLFLQFVTGSPRLPVGGFRSL----NPPLTIVRKTFESTENPDDFLPSVMTCVNYLKLPDYS 2051

  Fly   928 SYDQLVEKLTFAIEE 942
            |.:.:.:||..|..|
  Rat  2052 SIEIMRDKLLIAARE 2066

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Su(dx)	NP_001259898.1	C2_E3_ubiquitin_ligase	48..173	CDD:175988	40/209 (19%)
		WW	364..396	CDD:197736	8/36 (22%)
		WW	397..426	CDD:278809	8/71 (11%)
		WW	478..509	CDD:197736	7/35 (20%)
		WW	522..554	CDD:197736	9/33 (27%)
		HECTc	594..946	CDD:238033	114/415 (27%)
		HECTc	620..946	CDD:214523	108/382 (28%)
Trip12	XP_038939619.1	SRP1	489..>714	CDD:227396
		WWE	814..876	CDD:397111
		HECTc	1672..2072	CDD:238033	114/407 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900