Protein Alignment Su(dx) and Hectd2

DIOPT Version :10

• Sequence 1: NP_476753.1
• Gene: Su(dx) / 33379
• FlyBaseID: FBgn0003557
• Length: 949
• Species: Drosophila melanogaster
• Sequence 2: XP_038936565.1
• Gene: Hectd2 / 309514
• RGDID: 1305536
• Length: 813
• Species: Rattus norvegicus
• Alignment Length: 370
• Identity: 122/370 - (32%)
• Similarity: 191/370 - (51%)
• Gaps: 30/370 - (8%)

  Fly   594 IKITVTRQTLFEDSYHQIMRLPAYELRRRLYIIFRGEEGLDYGGVSREWFFLLSHEVLNPMYCLF 658
            :.:.|.|..|..||..::.|..| :|:::|.:.|.||.|||.||:::|||.||..::.:|.|.:|
  Rat   454 LNMKVRRTHLVSDSLDELTRKRA-DLKKKLKVTFVGEAGLDMGGLTKEWFLLLIRQIFHPDYGMF 517

  Fly   659 EYANKNNYSLQINPASYVNPDHLQYFKFIGRFIAMALYHGRFIYSGFTMPFYKRMLNK------- 716
            .| :|:::   .:..|....|:...|:.:|..:.:|:|:...:...|....||::|:.
  Rat   518 TY-HKDSH---CHWFSSFKCDNYSEFRLVGILMGLAVYNSITLDIRFPPCCYKKLLSPPVVPSDQ 578

  Fly   717 -------KLTIKDIETIDPEFYNSL--IWVKDNNIDECGLELWFSVDFEVLGQIIHHELKENGEK 772
                   .:||.|:..|.||..:.|  :...:.|::| .....|.|..|..|.|..:.||..|:|
  Rat   579 STPVGICSVTIDDLCQIMPELAHGLKELLSYEGNVEE-DFYSTFQVFQEEFGVIKSYNLKPGGDK 642

  Fly   773 ERVTEENKEEYITLMTEWRMTRGIEQQTKTFLEGFNEVVPLEWLKYFDERELELILCGMQDVDVE 837
            ..||.:|:.||:.|.|::.:.:.|.:|...|..||:.|.....|......|:|:::||..::|:.
  Rat   643 IPVTNQNRREYVQLYTDFLLNKSIYKQFAAFYCGFHSVCASNALMLLRPEEVEILVCGSPELDMH 707

  Fly   838 DWQRNTIYRHYNRNSKQVVWFWQFVRETDNEKRARLLQFVTGTCRVPVGGFAELMGSNGPQRFCI 902
            ..||:|.|..|.:....:.:||..|.....|.:.:||.|.||:.||||||.|:|       .|.|
  Rat   708 ALQRSTQYDGYAKTDLTIRYFWDVVLGFPLELQKKLLHFTTGSDRVPVGGMADL-------NFKI 765

  Fly   903 EKVGKET-WLPRSHTCFNRLDLPPYKSYDQLVEKLTFAIEETEGF 946
            .|....| |||.:|||||:|.||||||...|.:||...|..:|||
  Rat   766 SKNETSTNWLPVAHTCFNQLCLPPYKSKKDLKQKLIIGISNSEGF 810

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Su(dx)	NP_476753.1	C2_E3_ubiquitin_ligase	48..173	CDD:175988
		WW	364..396	CDD:197736
		HUL4	<395..946	CDD:227354	120/368 (33%)
Hectd2	XP_038936565.1	HECTc	454..811	CDD:238033	122/370 (33%)