Protein Alignment Su(dx) and pub1

DIOPT Version :10

• Sequence 1: NP_476753.1
• Gene: Su(dx) / 33379
• FlyBaseID: FBgn0003557
• Length: 949
• Species: Drosophila melanogaster
• Sequence 2: NP_594396.1
• Gene: pub1 / 2541818
• PomBaseID: SPAC11G7.02
• Length: 767
• Species: Schizosaccharomyces pombe
• Alignment Length: 933
• Identity: 349/933 - (37%)
• Similarity: 474/933 - (50%)
• Gaps: 191/933 - (20%)

  Fly    41 SGSANQGYHQLSVTIEEASLRNNGFLKPNPYVELLIDSKSKRKTDLVKNSYLPKWNEEFTVLITP 105
            |.||.....::::...:...:.:.|..|:|:..|.:|.:....|..:|.:..|.|||.|.|.:|.
pombe     2 SNSAQSRRIRVTIVAADGLYKRDVFRFPDPFAVLTVDGEQTHTTTAIKKTLNPYWNETFEVNVTD 66

  Fly   106 NSTLHFKVLDHSSFRK--DAMLGERIINL--AHILQHYNGRCEFLELTIDLFVTSKSDNRQTKSG 166
            |||:..:|.|...|:|  ...||  :|||  ..:|....|..|.  ||.||   .||:......|
pombe    67 NSTIAIQVFDQKKFKKKGQGFLG--VINLRVGDVLDLAIGGDEM--LTRDL---KKSNENTVVHG 124

  Fly   167 ELVAILNGLKLDMSKLQIQPVAGQQNGNPPVQAVNPSVVSDAAAGRSCMIYGGVRARMRLRSSSG 231
            ::  |:|......|.||                    |.|.||:|          ||.: |:|..
pombe   125 KI--IINLSTTAQSTLQ--------------------VPSSAASG----------ARTQ-RTSIT 156

  Fly   232 NSNGGETRSPLPNGGGDHRRSTQAPPVWEQQQQQSQNQQQPLRMVNGSGAAVPQTAPYPQQPPAP 296
            |.                          .|..|.|...:.|.....||          |.:..||
pombe   157 ND--------------------------PQSSQSSSVSRNPASSRAGS----------PTRDNAP 185

  Fly   297 ALARPLTQVYGALPENTQPAAVYLPAGGGAAVGPPGVAGPPIEQPGVGLPVSQSTDPQLQTQPAD 361
            |                                                           ..||.
pombe   186 A-----------------------------------------------------------ASPAS 191

  Fly   362 DEPLP-AGWEIRLDQYGRRYYVDHNTRSTYWEKPTPLPPGWEIRKDGRGRVYYVDHNTRKTTWQR 425
            .||.. :.:|   |||||                  ||||||.|.|..||.||||||||.|||.|
pombe   192 SEPRTFSSFE---DQYGR------------------LPPGWERRTDNLGRTYYVDHNTRSTTWIR 235

  Fly   426 PNSERLMHFQ----HWQGQRAHVVSQGNQRYLYSQQQQQPTAVTAQVTQDDEDALGPLPDGWEKK 486
            ||...:....    |.....|:|..........:.::.:.:.:|:..|....   |.||.|||::
pombe   236 PNLSSVAGAAAAELHSSASSANVTEGVQPSSSNAARRTEASVLTSNATTAGS---GELPPGWEQR 297

  Fly   487 IQSDNRVYFVNHKNRTTQWEDPR---------------TQGQEVSLINEGPLPPGWEIRYTAAGE 536
            ...:.|.|||:|..|||.|.|||               .|.|.||.:  ||||.|||:|.|....
pombe   298 YTPEGRPYFVDHNTRTTTWVDPRRQQYIRSYGGPNNATIQQQPVSQL--GPLPSGWEMRLTNTAR 360

  Fly   537 RFFVDHNTRRTTFEDPRPGAPKGAKGVYGVPRAYERSFRWKLSQFRYLCQSNALPSHIKITVTRQ 601
            .:||||||:.||::|||  .|....  ..||: |:|.||.||..|......:.||....|.|.|.
pombe   361 VYFVDHNTKTTTWDDPR--LPSSLD--QNVPQ-YKRDFRRKLIYFLSQPALHPLPGQCHIKVRRN 420

  Fly   602 TLFEDSYHQIMRLPAYELRRRLYIIFRGEEGLDYGGVSREWFFLLSHEVLNPMYCLFEYANKNNY 666
            .:|||||.:|||..|.:|::||.|.|.||:||||||:|||:|||||||:.||.||||||::.:||
pombe   421 HIFEDSYAEIMRQSATDLKKRLMIKFDGEDGLDYGGLSREYFFLLSHEMFNPFYCLFEYSSVDNY 485

  Fly   667 SLQINPASYVNPDHLQYFKFIGRFIAMALYHGRFIYSGFTMPFYKRMLNKKLTIKDIETIDPEFY 731
            :|||||.|.:||:||.|||||||.|.:|::|.||:.:.|.:.|||.:|.||:|::|:|::|.|:|
pombe   486 TLQINPHSGINPEHLNYFKFIGRVIGLAIFHRRFVDAFFVVSFYKMILQKKVTLQDMESMDAEYY 550

  Fly   732 NSLIWVKDNNIDECGLELWFSVDFEVLGQIIHHELKENGEKERVTEENKEEYITLMTEWRMTRGI 796
            .||:|:.||:|... |:|.|||:....|:::..:||.||....||||||.||:.|:|.||:.:.|
pombe   551 RSLVWILDNDITGV-LDLTFSVEDNCFGEVVTIDLKPNGRNIEVTEENKREYVDLVTVWRIQKRI 614

  Fly   797 EQQTKTFLEGFNEVVPLEWLKYFDERELELILCGMQDVDVEDWQRNTIYRHYNRNSKQVVWFWQF 861
            |:|...|.|||:|::|.|.:..||||||||::.|:.::|:|||:::|.||.|:.|.:.:.|||:.
pombe   615 EEQFNAFHEGFSELIPQELINVFDERELELLIGGISEIDMEDWKKHTDYRSYSENDQIIKWFWEL 679

  Fly   862 VRETDNEKRARLLQFVTGTCRVPVGGFAELMGSNGPQRFCIEKVGKETWLPRSHTCFNRLDLPPY 926
            :.|..|||::|||||.|||.|:||.||.:|.||:||::|.|||.|:...||::||||||||||||
pombe   680 MDEWSNEKKSRLLQFTTGTSRIPVNGFKDLQGSDGPRKFTIEKAGEPNKLPKAHTCFNRLDLPPY 744

  Fly   927 KSYDQLVEKLTFAIEETEGFCQE 949
            .|...|..||:.|:|||.||.||
pombe   745 TSKKDLDHKLSIAVEETIGFGQE 767

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Su(dx)	NP_476753.1	C2_E3_ubiquitin_ligase	48..173	CDD:175988	37/128 (29%)
		WW	364..396	CDD:197736	7/32 (22%)
		HUL4	<395..946	CDD:227354	271/569 (48%)
pub1	NP_594396.1	HUL4	1..767	CDD:227354	347/931 (37%)