Protein Alignment Su(dx) and pub3

DIOPT Version :10

• Sequence 1: NP_476753.1
• Gene: Su(dx) / 33379
• FlyBaseID: FBgn0003557
• Length: 949
• Species: Drosophila melanogaster
• Sequence 2: NP_595793.1
• Gene: pub3 / 2539956
• PomBaseID: SPBC16E9.11C
• Length: 786
• Species: Schizosaccharomyces pombe
• Alignment Length: 907
• Identity: 340/907 - (37%)
• Similarity: 457/907 - (50%)
• Gaps: 166/907 - (18%)

  Fly    65 FLKPNPYVELLIDSKSKRKTDLVKNSYLPKWNEEFTVLITPNSTLHFKVLDHSSFRKDAMLGERI 129
            |.:|:|:..|.:|.:....|.::|.|..|.|||.|.|.:.|:|.:..::.|...|:|..
pombe    24 FRQPDPFAILTVDGEQTHTTKVIKKSVNPYWNEGFEVTVKPSSVISIRLFDQKKFKKKD------ 82

  Fly   130 INLAHILQHYNGRCEFLELTIDLFVTSKSDNRQTKSGELVAILNGLK----LDMSKLQIQPVAGQ 190
                   |.:.|...|....:..|          :|...|::...||    .::|.|
pombe    83 -------QGFLGLVSFRMREVGSF----------RSNREVSLTRPLKKSSTTNLSVL-------- 122

  Fly   191 QNGNPPVQAVNPSVVSDAAAGRSCMIYGGVRARMRLRSSSGNSNGGETRSPLPNGGGDHRRSTQA 255
              || .|..|.||                     ::|:.:||.:     |...|      |:|..
pombe   123 --GN-LVLKVAPS---------------------KIRAPAGNHS-----STTAN------RTTST 152

  Fly   256 PPVWEQQQQQSQNQQQPLRMVNGSGAAVPQTAPYPQQPPAPALARPLTQVYGALPENTQPAAVYL 320
            |..                    :.|...:|.|.|     .|......|.......|...||...
pombe   153 PTT--------------------TTARTTRTTPRP-----TATTNTSNQSTSNSTRNGTSAATSN 192

  Fly   321 PAGGGAAVGPPGVAGPPIEQPGVGLPVSQSTDPQLQTQPA---DDEPLPAGWEIRLDQYGRRYYV 382
            ..|.||..|....:.|             .|:.|.....|   .:..:.:.:|   |||||
pombe   193 GTGTGAGTGASHRSSP-------------VTNRQTNNTSALSNSNAHIMSSFE---DQYGR---- 237

  Fly   383 DHNTRSTYWEKPTPLPPGWEIRKDGRGRVYYVDHNTRKTTWQRPNSERLMHFQHWQGQRAHVVSQ 447
                          ||||||.|.|..||.||||||||.|||.||.|..         ...|..|.
pombe   238 --------------LPPGWERRADSLGRTYYVDHNTRTTTWTRPASST---------NPVHNTSS 279

  Fly   448 GNQRYLYSQQQQQPTAVTAQVTQDDEDALGPLPDGWEKKIQSDNRVYFVNHKNRTTQWEDPR--- 509
            .:|| |..|.:..|......:.|.|..  ..||.|||.:.....|.|||:|..|||.|.|||
pombe   280 DSQR-LNHQNRHLPDDSNPSLMQSDSG--NDLPFGWEMRYTDTGRPYFVDHNTRTTTWVDPRNPL 341

  Fly   510 --------TQG---QEVSLINEGPLPPGWEIRYTAAGERFFVDHNTRRTTFEDPR-PGAPKGAKG 562
                    |.|   |..||.:.||||.|||:|.|.:...:||||||:.||::||| |.|..
pombe   342 VRPNGGSSTVGSLMQPQSLSHLGPLPSGWEMRLTNSARVYFVDHNTKTTTWDDPRLPSALD---- 402

  Fly   563 VYGVPRAYERSFRWKLSQFRYLCQSNALPSHIKITVTRQTLFEDSYHQIMRLPAYELRRRLYIIF 627
             ..||: |:..||.||..||.......||....:.|.|..:|||||.:|||..|::|::||.|.|
pombe   403 -QDVPQ-YKCDFRRKLIYFRSQPGMRPLPGQCNVKVRRDHIFEDSYAEIMRYSAHDLKKRLMIRF 465

  Fly   628 RGEEGLDYGGVSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLQYFKFIGRFIA 692
            .||:||||||:|||:||||||::.:|:||||||:..:||:|||||.|.:||:||.||:||||.|.
pombe   466 DGEDGLDYGGLSREFFFLLSHKMFDPIYCLFEYSAVDNYTLQINPHSSINPEHLNYFRFIGRVIG 530

  Fly   693 MALYHGRFIYSGFTMPFYKRMLNKKLTIKDIETIDPEFYNSLIWVKDNNIDECGLELWFSVDFEV 757
            :|::|.||:.:.|.:..||::|.||:::.|:|:||.|||.||.||.:|:|... |:|.|||:.:.
pombe   531 LAIFHRRFLDAFFVVSLYKKLLRKKVSLADMESIDAEFYRSLKWVLENDITGI-LDLTFSVEEDH 594

  Fly   758 LGQIIHHELKENGEKERVTEENKEEYITLMTEWRMTRGIEQQTKTFLEGFNEVVPLEWLKYFDER 822
            .|::...||..|||...||||||::|:.|:||||:::.:|||...|..||.|:|..:.:..||||
pombe   595 FGEVRTVELITNGENIEVTEENKKKYVDLVTEWRVSKRVEQQFNAFYSGFVELVSPDLVNVFDER 659

  Fly   823 ELELILCGMQDVDVEDWQRNTIYRHYNRNSKQVVWFWQFVRETDNEKRARLLQFVTGTCRVPVGG 887
            ||||::.|:.|||||||:.:|.||.|......:.|||:.:....||.|::||||.|||.|:||.|
pombe   660 ELELLIGGISDVDVEDWKSHTEYRTYIATDPVIKWFWEIIAGWKNEDRSKLLQFATGTSRIPVNG 724

  Fly   888 FAELMGSNGPQRFCIEKVGKETWLPRSHTCFNRLDLPPYKSYDQLVEKLTFAIEETEGFCQE 949
            |.:|.||:||::|.|||.|....||.:||||||||||.|.|.|.|.|||:.|:|.|.||..|
pombe   725 FRDLQGSDGPRKFTIEKAGTPDQLPVAHTCFNRLDLPDYPSKDTLHEKLSLAVENTVGFGNE 786

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Su(dx)	NP_476753.1	C2_E3_ubiquitin_ligase	48..173	CDD:175988	25/107 (23%)
		WW	364..396	CDD:197736	6/31 (19%)
		HUL4	<395..946	CDD:227354	271/565 (48%)
pub3	NP_595793.1	HUL4	4..786	CDD:227354	339/905 (37%)