DRSC/TRiP Functional Genomics Resources

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Protein Alignment Su(dx) and Plekha7

DIOPT Version :9

Sequence 1:NP_001259898.1 Gene:Su(dx) / 33379 FlyBaseID:FBgn0003557 Length:949 Species:Drosophila melanogaster
Sequence 2:XP_017177675.1 Gene:Plekha7 / 233765 MGIID:2445094 Length:1359 Species:Mus musculus


Alignment Length:227 Identity:65/227 - (28%)
Similarity:91/227 - (40%) Gaps:51/227 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly   479 LPDGWEKKIQSDNRVYFVNHKNRTTQWEDPRTQGQEVSLINEG-----PLPPGWEIRYTAAGERF 538
            ||:.|...:..|.||:|:|.:.|.|.|..||| |:.|   |.|     .||.|||..:|..|..|
Mouse    10 LPEHWSYGVCRDGRVFFINDQLRCTTWLHPRT-GEPV---NSGHMIRSDLPRGWEEGFTEEGASF 70

  Fly   539 FVDHNTRRTTFEDPRPGAPKGAKGVYGV---PRAY----ERSFRWKLSQFRYLCQSNALPSHIKI 596
            |:|||.:.|||..|..|........|.:   |..:    ||:.|           .:::.|....
Mouse    71 FIDHNQQTTTFRHPVTGQFSSENSEYVLREEPHPHMSKPERNQR-----------PSSMVSETST 124

  Fly   597 TVTRQTLFEDSYHQIMRLPA---------YELRRRLY--IIFRG-EEGLDYGGV---SREWFFLL 646
            ..|..||......:|::..:         ..:||.|.  ::.|| ....|..|:   .|.||.|.
Mouse   125 AGTTSTLEAKPGPKIVKSSSKVHSFGKRDQAIRRNLNVPVVVRGWLHKQDSSGMRLWKRRWFVLA 189

  Fly   647 SHEVLNPMYCLFEYANKNNYSL--QINPASYV 676
            .       ||||.|.:....::  .|...|||
Mouse   190 D-------YCLFYYKDSREEAVLGSIPLPSYV 214

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Su(dx)NP_001259898.1 C2_E3_ubiquitin_ligase 48..173 CDD:175988
WW 364..396 CDD:197736
WW 397..426 CDD:278809
WW 478..509 CDD:197736 11/29 (38%)
WW 522..554 CDD:197736 16/31 (52%)
HECTc 594..946 CDD:238033 24/100 (24%)
HECTc 620..946 CDD:214523 20/65 (31%)
Plekha7XP_017177675.1 WW 10..39 CDD:366073 11/28 (39%)
WW 55..84 CDD:366073 15/28 (54%)
PH_PEPP1_2_3 158..280 CDD:270068 19/64 (30%)
Smc <692..>894 CDD:224117
PHA03247 <903..1009 CDD:223021
PRK10263 <912..>1118 CDD:236669
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5021
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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